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View article: Spatially Resolved Microglial Expression Around Aβ Plaques in Human Alzheimer’s Disease Tissue
Spatially Resolved Microglial Expression Around Aβ Plaques in Human Alzheimer’s Disease Tissue Open
Summary Using microglia-enriched spatial transcriptomics on human Alzheimer’s disease tissue, we identify distinct gene expression changes across microglia located in direct contact with plaques, in periplaque regions, and in areas distant…
View article: Spatially Resolved Microglial Expression Around Aβ Plaques in Human Alzheimer’s Disease Tissue
Spatially Resolved Microglial Expression Around Aβ Plaques in Human Alzheimer’s Disease Tissue Open
View article: Author Correction: Cutaneous T cell lymphoma atlas reveals malignant TH2 cells supported by a B cell-rich tumor microenvironment
Author Correction: Cutaneous T cell lymphoma atlas reveals malignant TH2 cells supported by a B cell-rich tumor microenvironment Open
View article: Cutaneous T cell lymphoma atlas reveals malignant TH2 cells supported by a B cell-rich tumor microenvironment
Cutaneous T cell lymphoma atlas reveals malignant TH2 cells supported by a B cell-rich tumor microenvironment Open
View article: Plaque contact and unimpaired Trem2 is required for the microglial response to amyloid pathology
Plaque contact and unimpaired Trem2 is required for the microglial response to amyloid pathology Open
Using spatial cell-type-enriched transcriptomics, we compare plaque-induced gene (PIG) expression in microglia-touching plaques, neighboring plaques, and far from plaques in an aged Alzheimer's mouse model with late plaque development. In …
View article: Upregulation of<i>Trem2</i>expression occurs exclusively on microglial contact with plaques
Upregulation of<i>Trem2</i>expression occurs exclusively on microglial contact with plaques Open
Using spatial cell-type-enriched transcriptomics, we compare plaque-induced gene (PIG) expression in microglia touching plaques, neighboring plaques, and far from plaques in 18-month-old APP NLF/NLF knock-in mice with and without the Alzhe…
View article: Upregulation of <i>Trem2</i> Expression Occurs Exclusively on Microglial Contact with Plaques
Upregulation of <i>Trem2</i> Expression Occurs Exclusively on Microglial Contact with Plaques Open