Ayaka Saito
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View article: Anxiety, depression, and fear after coronavirus disease 2019 infection and their association with long coronavirus disease symptoms
Anxiety, depression, and fear after coronavirus disease 2019 infection and their association with long coronavirus disease symptoms Open
Introduction The coronavirus disease 2019 (COVID-19) pandemic has had widespread physical and psychological repercussions. Additionally, long COVID symptoms such as fatigue, dyspnea, and cognitive impairment have been well-documented; howe…
View article: Apparent reduction in heart rate during oviposition revealed by non-invasive heart rate monitoring of gravid loggerhead turtles
Apparent reduction in heart rate during oviposition revealed by non-invasive heart rate monitoring of gravid loggerhead turtles Open
Reproductive processes place significant physiological demands on animals, often accompanied by hormonal and neural changes. In this study, we examined changes in heart rate of gravid loggerhead turtles (C aretta caretta ) during nesting a…
View article: Basal-shift transformation leads to EGFR therapy-resistance in human lung adenocarcinoma
Basal-shift transformation leads to EGFR therapy-resistance in human lung adenocarcinoma Open
View article: Clinical Sequence Revealed the Prevalence and Biological Significance of Somatic Pathogenic Variants in Thoracic Cancer: Implications for Germline Status
Clinical Sequence Revealed the Prevalence and Biological Significance of Somatic Pathogenic Variants in Thoracic Cancer: Implications for Germline Status Open
This study underscores the importance of identifying PGPVs through CGP testing conducted in patients with thoracic cancer. Using frequency and functional analysis. Further investigation is warranted regarding the clinical significance of t…
View article: Development of a non-invasive heart rate measurement method for sea turtles with dense keratinous scutes through effective electrode placement
Development of a non-invasive heart rate measurement method for sea turtles with dense keratinous scutes through effective electrode placement Open
Measuring the heart rate of sea turtles is important for understanding their physiological adaptations to the environment. Non-invasive methods to measure the electrocardiogram (ECG) of sea turtles have been developed by attaching electrod…
View article: Comparison of estimated blood loss during living kidney transplantation according to the number of double-filtration plasmapheresis
Comparison of estimated blood loss during living kidney transplantation according to the number of double-filtration plasmapheresis Open
Background Plasmapheresis is an important preoperative desensitization treatment for ABO-incompatible living kidney transplantation. However, in cases with plasma exchange therapy (PET), it is necessary to consider the risks of perioperati…
View article: ECR Spotlight – Ayaka Saito
ECR Spotlight – Ayaka Saito Open
ECR Spotlight is a series of interviews with early-career authors from a selection of papers published in Journal of Experimental Biology and aims to promote not only the diversity of early-career researchers (ECRs) working in experimental…
View article: Heart rate reduction during voluntary deep diving in free-ranging loggerhead sea turtles
Heart rate reduction during voluntary deep diving in free-ranging loggerhead sea turtles Open
Air-breathing vertebrates exhibit cardiovascular responses to diving including heart rate reduction (diving bradycardia). Field studies on aquatic mammals and birds have shown that the intensity of bradycardia can vary depending on diving …
View article: Clinical utility of the Oncomine Dx Target Test<scp>multi‐CDx</scp>system and the possibility of utilizing those original sequence data
Clinical utility of the Oncomine Dx Target Test<span>multi‐CDx</span>system and the possibility of utilizing those original sequence data Open
Background Companion diagnostic tests play a crucial role in guiding treatment decisions for patients with non‐small cell lung cancer (NSCLC). The Oncomine Dx Target Test (ODxTT) Multi‐CDx System has emerged as a prominent companion diagno…
View article: Clinical Sequence Revealed the Prevalence and Biological Significance of Presumed Germline Pathogenic Variants in Thoracic Cancer
Clinical Sequence Revealed the Prevalence and Biological Significance of Presumed Germline Pathogenic Variants in Thoracic Cancer Open
View article: The prognostic utility of prehospital qSOFA in addition to emergency department qSOFA for sepsis in patients with suspected infection: A retrospective cohort study
The prognostic utility of prehospital qSOFA in addition to emergency department qSOFA for sepsis in patients with suspected infection: A retrospective cohort study Open
Background The quick sequential organ failure assessment (qSOFA) was widely used to estimate the risks of sepsis in patients with suspected infection in the prehospital and emergency department (ED) settings. Due to the insufficient sensit…
View article: Challenges hindering emergency physicians; involvement in multicenter collaborative studies in Japan: A nationwide survey analysis
Challenges hindering emergency physicians; involvement in multicenter collaborative studies in Japan: A nationwide survey analysis Open
Aim Multicenter collaborative research accelerates patient recruitment and strengthens evidence. Nevertheless, the factors influencing emergency and critical care physicians’ involvement in such research in Japan remain unclear. Methods A …
View article: Long-Term Treatment-Free Survival After Multimodal Therapy in a Patient with Stage IV Lung Adenocarcinoma
Long-Term Treatment-Free Survival After Multimodal Therapy in a Patient with Stage IV Lung Adenocarcinoma Open
We report the first case of a patient with non-small cell lung cancer (NSCLC) with malignant pleural effusion (MPE) who achieved disease- and treatment-free survival for nearly 10 years. A 50-year-old man was diagnosed with NSCLC with MPE …
View article: Effects of a parasympathetic blocker on the heart rate of loggerhead sea turtles during voluntary diving
Effects of a parasympathetic blocker on the heart rate of loggerhead sea turtles during voluntary diving Open
Diving bradycardia is a reduction in the heart rate mediated by the parasympathetic system during diving. Although diving bradycardia is pronounced in aquatic mammals and birds, the existence of this response in aquatic reptiles, including…
View article: Heart rate as a proxy for estimating oxygen consumption rates in loggerhead turtles (<i>Caretta caretta</i>)
Heart rate as a proxy for estimating oxygen consumption rates in loggerhead turtles (<i>Caretta caretta</i>) Open
Heart rates of air-breathing diving animals can change on a short time scale due to the diving response during submergence. Heart rate is used frequently as a proxy for indirectly estimating metabolic rates on a fine time scale. However, m…
View article: A Non-Invasive Heart Rate Measurement Method Is Improved by Placing the Electrodes on the Ventral Side Rather Than the Dorsal in Loggerhead Turtles
A Non-Invasive Heart Rate Measurement Method Is Improved by Placing the Electrodes on the Ventral Side Rather Than the Dorsal in Loggerhead Turtles Open
Heart rate measurement is an essential method for evaluating the physiological status of air-breathing diving animals. However, owing to technical difficulties, many marine animals require an invasive approach to record an electrocardiogra…
View article: Comprehensive Analysis of Long COVID in a Japanese Nationwide Prospective Cohort Study
Comprehensive Analysis of Long COVID in a Japanese Nationwide Prospective Cohort Study Open
View article: P8‐174: Highly elevated serum levels of CA 19‐9 in metastatic adenocarcinoma of the lung
P8‐174: Highly elevated serum levels of CA 19‐9 in metastatic adenocarcinoma of the lung Open
overall survival (OS) were 9.0 months and 35 months, respectively.Skin rash was observed in all patients, mostly at grade 1 or 2. We collected blood samples from all patients.
View article: P8‐165: Paclitaxel induced apoptosis in EGFR‐mutated PC9 cells by inhibiting the c‐Myc signaling pathway
P8‐165: Paclitaxel induced apoptosis in EGFR‐mutated PC9 cells by inhibiting the c‐Myc signaling pathway Open
symptoms of pain (37.%) and with mild pain (37.5%) were the most found in bone metastases patients.The mean serum calcium level was 9.48 AE1.38 in bone metastases and 8.82 AE1.13 in no bone metastases.There was a significant difference in …
View article: Specific Adsorption of Glycine onto Atomically Flat Al<sub>2</sub>O<sub>3</sub>(0001) Surfaces in Aqueous Solution
Specific Adsorption of Glycine onto Atomically Flat Al<sub>2</sub>O<sub>3</sub>(0001) Surfaces in Aqueous Solution Open
To understand the adsorption of functional proteins onto metal oxides in living bodies at the atomic/molecular scale, we examined the adsorption behaviors of amino acids, the fundamental elements of proteins, onto atomically flat surfaces …
View article: Incorporation of Incompatible Strontium and Barium Ions into Calcite (CaCO3) through Amorphous Calcium Carbonate
Incorporation of Incompatible Strontium and Barium Ions into Calcite (CaCO3) through Amorphous Calcium Carbonate Open
Calcite is a ubiquitous mineral in nature. Heavy alkaline-earth elements with large ionic radii such as Sr2+ and Ba2+ are highly incompatible to calcite. Our previous study clarified that incompatible Sr2+ ions can be structurally incorpor…
View article: Metabolic and chemical regulation of tRNA modification associated with taurine deficiency and human disease
Metabolic and chemical regulation of tRNA modification associated with taurine deficiency and human disease Open
Modified uridine containing taurine, 5-taurinomethyluridine (τm(5)U), is found at the anticodon first position of mitochondrial (mt-)transfer RNAs (tRNAs). Previously, we reported that τm(5)U is absent in mt-tRNAs with pathogenic mutations…
View article: Donor- or Acceptor-type 9,9′-Bifluorenylidene Derivatives for Attaining Singlet Fission Character in Organic Photovoltaics
Donor- or Acceptor-type 9,9′-Bifluorenylidene Derivatives for Attaining Singlet Fission Character in Organic Photovoltaics Open
Donor-type and acceptor-type 9,9′-bifluorenylidene derivatives, MOBF and CNBF, were synthesized. Suitable energy levels on the excited states of the compounds for singlet fission were revealed by density functional theory calculation. Ther…
View article: Systematic Relationship between Sr Content and the Lattice Constants in Sr Substituted Hydroxyapatite Thin Films
Systematic Relationship between Sr Content and the Lattice Constants in Sr Substituted Hydroxyapatite Thin Films Open
To increase the biocompatibility of hydroxyapatite (HA), Ca10(PO4)6(OH)2, the Sr substitution of Ca into the HA structure was effected to yield Ca10-xSrx(PO4)6(OH)2(Sr-HA). For medical and dental applications, it is important that Sr-HA is…
View article: Organic Photovoltaics: Singlet Fission of Non‐polycyclic Aromatic Molecules in Organic Photovoltaics (Adv. Mater. 8/2016)
Organic Photovoltaics: Singlet Fission of Non‐polycyclic Aromatic Molecules in Organic Photovoltaics (Adv. Mater. 8/2016) Open
On page 1585, Y.-J. Pu, J. Kido, and co-workers demonstrate the singlet fission of thienoquinoid compounds by measuring the magnetic-field dependence of the photocurrent of photovoltaic devices. Three kinds of thienoquinoid core and fluore…