Ayalew Jejaw Zeleke
YOU?
Author Swipe
View article: High prevalence and emerging positive association of kelch13 R622I and HRP2-based RDT negativity in Plasmodium falciparum in northern Ethiopia
High prevalence and emerging positive association of kelch13 R622I and HRP2-based RDT negativity in Plasmodium falciparum in northern Ethiopia Open
The rise of antimalarial drug-resistant Plasmodium falciparum threatens malaria elimination efforts. Mutations in the gene kelch13 ( k13 ) confer artemisinin partial resistance (ART-R), compromising the efficacy of frontline artemisinin-ba…
View article: Highly multiplexed molecular inversion probe panel in Plasmodium falciparum targeting common SNPs approximates whole-genome sequencing assessments for selection and relatedness
Highly multiplexed molecular inversion probe panel in Plasmodium falciparum targeting common SNPs approximates whole-genome sequencing assessments for selection and relatedness Open
The use of next-generation sequencing technologies (NGS) to study parasite populations and their response and evolution to interventions is important to support malaria control and elimination efforts. While whole-genome sequencing (WGS) i…
View article: Artemisinin resistant<i>kelch13</i>R622I and RDT negativity approaching predominance in northern Ethiopia and emerging C580Y of African origin threaten falciparum malaria control
Artemisinin resistant<i>kelch13</i>R622I and RDT negativity approaching predominance in northern Ethiopia and emerging C580Y of African origin threaten falciparum malaria control Open
The rise of antimalarial drug-resistant Plasmodium falciparum poses a major threat to malaria treatment, control, and elimination efforts. Mutations in the kelch13 ( k13 ) gene confer artemisinin partial resistance (ART-R), compromising th…
View article: Highly multiplexed molecular inversion probe panel in Plasmodium falciparum targeting common SNPs approximates whole-genome sequencing assessments for selection and relatedness
Highly multiplexed molecular inversion probe panel in Plasmodium falciparum targeting common SNPs approximates whole-genome sequencing assessments for selection and relatedness Open
Introduction The use of next-generation sequencing technologies (NGS) to study parasite populations and their response and evolution to interventions is important to support malaria control and elimination efforts. While whole-genome seque…
View article: Highly multiplex molecular inversion probe panel in Plasmodium falciparum targeting common SNPs approximates whole genome sequencing assessments for selection and relatedness
Highly multiplex molecular inversion probe panel in Plasmodium falciparum targeting common SNPs approximates whole genome sequencing assessments for selection and relatedness Open
Introduction The use of next-generation sequencing technologies (NGS) to study parasite populations and their response and evolution to interventions is important to support malaria control and elimination efforts. While whole genome seque…
View article: Exploring coagulation parameters as predictive biomarkers of Plasmodium infection: A comprehensive analysis of coagulation parameters
Exploring coagulation parameters as predictive biomarkers of Plasmodium infection: A comprehensive analysis of coagulation parameters Open
Background Malaria affects the intravascular environment, leading to abnormal coagulation activation, prolonged prothrombin time, and activated partial thromboplastin time. Despite the high prevalence of malaria in the study area, there ha…
View article: A Retrospective Analysis of Malaria Trends in Maksegnit Health Center over the Last Seven Years, Northwest Ethiopia: 2014-2020
A Retrospective Analysis of Malaria Trends in Maksegnit Health Center over the Last Seven Years, Northwest Ethiopia: 2014-2020 Open
Background. In Ethiopia, despite various public health intervention approaches have been implemented to eliminate malaria, its public health problem remains considerable. There are such numerous studies; however, investigating the trend of…
View article: Evaluation of Hookworm Diagnosis Techniques from Patients in Debre Elias and Sanja Districts of the Amhara Region, Ethiopia
Evaluation of Hookworm Diagnosis Techniques from Patients in Debre Elias and Sanja Districts of the Amhara Region, Ethiopia Open
Background. Inappropriate diagnosis could intimidate the prevention and control of hookworm infection. Thus, this study was aimed at evaluating the performance of hookworm diagnosis methods. Methods. An institution-based cross-sectional st…
View article: In vivo and in vitro efficacy of a single dose of albendazole against hookworm infection in northwest Ethiopia: open-label trial
In vivo and in vitro efficacy of a single dose of albendazole against hookworm infection in northwest Ethiopia: open-label trial Open
Background Control of hookworm and other soil-transmitted helminth infections primarily relies on preventive chemotherapy using a single dose of albendazole/mebendazole drugs on high-risk groups. Herein, the efficacy of a single dose (400 …
View article: A Ten-Year Trend of Cutaneous Leishmaniasis at University of Gondar Hospital, Northwest Ethiopia: 2009-2018
A Ten-Year Trend of Cutaneous Leishmaniasis at University of Gondar Hospital, Northwest Ethiopia: 2009-2018 Open
Background. Cutaneous leishmaniasis (CL), which is one form of leishmaniasis, may show variations over years across regions, and epidemiological studies are crucial to estimate the cases of the disease status over a long time. This study i…
View article: Prevalence and Associated Factors of Intestinal Helminths Among Kindergarten Children in Gondar Town, Northwest Ethiopia
Prevalence and Associated Factors of Intestinal Helminths Among Kindergarten Children in Gondar Town, Northwest Ethiopia Open
A significant number of children were infected by intestinal parasites in the study area. A. lumbricoides and intestinal Schistosomiasis were the most predominant of the isolated parasites.
View article: Prevalence, Infection Intensity and Associated Factors of Soil-Transmitted Helminthiasis Among School-Aged Children from Selected Districts in Northwest Ethiopia
Prevalence, Infection Intensity and Associated Factors of Soil-Transmitted Helminthiasis Among School-Aged Children from Selected Districts in Northwest Ethiopia Open
Our findings revealed STH infections are considerable health problems in the study areas. Thus, public health interventions such as provision of safe water supply, health education, and de-worming programs should be regularly implemented i…
View article: The Prevalence of Intestinal Parasites and Their Associated Factors among Diabetes Mellitus Patients at the University of Gondar Referral Hospital, Northwest Ethiopia
The Prevalence of Intestinal Parasites and Their Associated Factors among Diabetes Mellitus Patients at the University of Gondar Referral Hospital, Northwest Ethiopia Open
Background. Worldwide, more than one-sixth of the population is infected by intestinal parasites, of which the majority live in developing countries. On the other hand, the prevalence of diabetes mellitus has been increasing over recent de…
View article: Treatment efficacy and re-infection rates of soil-transmitted helminths following mebendazole treatment in schoolchildren, Northwest Ethiopia
Treatment efficacy and re-infection rates of soil-transmitted helminths following mebendazole treatment in schoolchildren, Northwest Ethiopia Open
Background Transmission of soil-transmitted helminth (STH) infection remains high in Ethiopia. This study aimed at assessing the therapeutic efficacy of mebendazole against soil-transmitted helminths and determining the re-infection rates …
View article: Prevalence, Intensity, and Associated Factors of Schistosoma mansoni among School Children in Northwest Ethiopia
Prevalence, Intensity, and Associated Factors of Schistosoma mansoni among School Children in Northwest Ethiopia Open
Background. Schistosomiasis is one of the Neglected Tropical Diseases in Ethiopia, and its burden may show variations from time to time across different regions. Thus, this study was aimed at determining the prevalence, intensity, and asso…
View article: Clinical, parasitological and molecular profiles of Cutaneous Leishmaniasis and its associated factors among clinically suspected patients attending Borumeda Hospital, North-East Ethiopia
Clinical, parasitological and molecular profiles of Cutaneous Leishmaniasis and its associated factors among clinically suspected patients attending Borumeda Hospital, North-East Ethiopia Open
The prevalence of cutaneous leishmaniasis was 22.4%, this alerts the need of intervention. It is statistically associated with house near to farm land, presence of other cutaneous leishmaniasis cases in the neighborhood and presence of hyr…
View article: Evaluation of Hookworm Diagnosis Techniques from Patients in Amhara Region, Ethiopia: Cross sectional study
Evaluation of Hookworm Diagnosis Techniques from Patients in Amhara Region, Ethiopia: Cross sectional study Open
Background : Inappropriate diagnosis could intimidate the prevention and control of Hookworm infection. This study was aimed at evaluating the performance of Hookworm diagnosis methods. Methods : An institution based cross sectional study …
View article: Trends and seasonal patterns in intestinal parasites diagnosed in primary health facilities in Northwest Ethiopia
Trends and seasonal patterns in intestinal parasites diagnosed in primary health facilities in Northwest Ethiopia Open
Introduction: Intestinal parasites have an insidious impact on human health. In response to high parasite frequencies in Northwest Ethiopia, mass drug administration (MDA) is provided for school children using albendazole/mebendazole (sinc…
View article: <p>Basic Coagulation Profiles and Platelet Count Among <em>Schistosoma mansoni</em>-Infected Adults Attending Sanja Primary Hospital, Northwest Ethiopia</p>
Basic Coagulation Profiles and Platelet Count Among <em>Schistosoma mansoni</em>-Infected Adults Attending Sanja Primary Hospital, Northwest Ethiopia Open
The prevalence of coagulation abnormality was higher in S. mansoni-infected adults than healthy controls. Coagulation test and platelet count should be used to monitor and manage schistosomiasis-related complications.
View article: Hookworm infection and associated risk factors among clinically confirmed podoconiosis patients and healthy residents in Debre Elias district, East Gojjam Zone
Hookworm infection and associated risk factors among clinically confirmed podoconiosis patients and healthy residents in Debre Elias district, East Gojjam Zone Open
Background Hookworm is a major public health problem in Ethiopia. The prevalence of Hookworm and associated factors among podoconiosis patients and healthy residents has not been studied.Objective to determine the prevalence of Hookworm an…
View article: Larvicidal effect of Endod (Phytolacca dodecandra) seed products against Anopheles arabiensis (Diptera: Culicidae) in Ethiopia
Larvicidal effect of Endod (Phytolacca dodecandra) seed products against Anopheles arabiensis (Diptera: Culicidae) in Ethiopia Open
The purpose of the present study was to determine the larvicidal effect of 'Endod' (Phytolacca dodecandra) seed products on Anopheles arabiensis, in Ethiopia. Experimental study was conducted using a total of 2400 third instars larvae of A…
View article: Intestinal Parasitosis and Their Associated Factors among People Living with HIV at University of Gondar Hospital, Northwest-Ethiopia
Intestinal Parasitosis and Their Associated Factors among People Living with HIV at University of Gondar Hospital, Northwest-Ethiopia Open
BACKGROUND: Most HIV clients die of AIDS related intestinal parasitic infections rather than due to the HIV infection itself. Therefore, this study was aimed at determining the prevalence of intestinal parasite and their associated factors…