Ayano Motohashi
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View article: Large-scale screening of SARS-CoV-2 variants in Tokyo, Japan: A 3-year and 9-month longitudinal survey
Large-scale screening of SARS-CoV-2 variants in Tokyo, Japan: A 3-year and 9-month longitudinal survey Open
Over nearly four years (March 10, 2021-December 31, 2024), we performed a comprehensive longitudinal analysis of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants among patients in a single hospital in Tokyo, Japan.…
View article: Diagnostic Accuracy of Direct Reverse Transcription-Polymerase Chain Reactionusing Guanidine-Based and Guanidine-Free Inactivators for SARS-CoV-2 Detection in Saliva Samples
Diagnostic Accuracy of Direct Reverse Transcription-Polymerase Chain Reactionusing Guanidine-Based and Guanidine-Free Inactivators for SARS-CoV-2 Detection in Saliva Samples Open
View article: The development of SARS-CoV-2 PCR testing methods at a designated medical institution for specific infectious diseases in Japan
The development of SARS-CoV-2 PCR testing methods at a designated medical institution for specific infectious diseases in Japan Open
Due to the coronavirus disease 2019 (COVID-19) pandemic, we have been conducting polymerase chain reaction (PCR) testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at this facility since March 2020. In the early days,…
View article: Negative Results of Nucleic Acid Amplification Tests for SARS-CoV-2 in Clinical Practice May Vary among Six Molecular Assays in Patients with COVID-19
Negative Results of Nucleic Acid Amplification Tests for SARS-CoV-2 in Clinical Practice May Vary among Six Molecular Assays in Patients with COVID-19 Open
Several commercial nucleic acid amplification tests (NAATs) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been developed. We used 6 kits available in Japan in 13 NAAT-positive specimens with crossing point values >3…
View article: Diagnostic accuracy of nasopharyngeal swab, nasal swab and saliva swab samples for the detection of SARS-CoV-2 using RT-PCR
Diagnostic accuracy of nasopharyngeal swab, nasal swab and saliva swab samples for the detection of SARS-CoV-2 using RT-PCR Open
NS samples are more reliable than SS samples and can be an alternative to NPS samples. They can be a useful diagnostic method in the future.
View article: Effective screening strategies for detection of asymptomatic COVID-19 travelers at airport quarantine stations: Exploratory findings in Japan
Effective screening strategies for detection of asymptomatic COVID-19 travelers at airport quarantine stations: Exploratory findings in Japan Open
The quantitative reverse transcription polymerase chain reaction method using nasopharyngeal swabs (NPS RT-qPCR) is regarded as the reference standard for diagnosing coronavirus disease 2019 (COVID-19). However, when using NPS RT-qPCR at b…
View article: Diagnostic accuracy of nasopharyngeal swab, nasal swab and saliva swab samples for the detection of SARS-CoV-2 using RT-PCR
Diagnostic accuracy of nasopharyngeal swab, nasal swab and saliva swab samples for the detection of SARS-CoV-2 using RT-PCR Open
The current gold standard in coronavirus disease (COVID-19) diagnostics is the real-time reverse transcription–polymerase chain reaction (RT-PCR) assay for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in nasop…
View article: Cutaneous <i>Mycobacteroides chelonae</i> Infection
Cutaneous <i>Mycobacteroides chelonae</i> Infection Open
A 55-year-old woman presented with a 3-month history of progressively worsening, intractable, ulcerated papules on her left lower leg (Picture 1).She had a history of rheumatoid arthritis and was treated with 4 mg/day of prednisolone, 8 mg…
View article: Molecular epidemiology of β-lactamase production in penicillin-susceptible Staphylococcus aureus under high-susceptibility conditions
Molecular epidemiology of β-lactamase production in penicillin-susceptible Staphylococcus aureus under high-susceptibility conditions Open
Little is known about the prevalence of β-lactamase production in penicillin-susceptible Staphylococcus aureus isolates under high-susceptibility conditions. We analyzed S. aureus isolates with penicillin G minimum inhibitory concentration…
View article: Molecular Epidemiology of β-lactamase Production in Penicillin-susceptible Staphylococcus aureus under High-susceptibility Conditions
Molecular Epidemiology of β-lactamase Production in Penicillin-susceptible Staphylococcus aureus under High-susceptibility Conditions Open
At the National Center for Global Health and Medicine (NCGM; Tokyo, Japan), prevalence of penicillin-susceptible Staphylococcus aureus isolates with penicillin G minimum inhibitory concentration (MIC) ≤ 0.12 μg/mL comprised 31% of isolates…