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View article: Vaccination Following Leukemia Treatment: Viral Vaccine Responses in Survivors of Acute Lymphoblastic Leukemia
Vaccination Following Leukemia Treatment: Viral Vaccine Responses in Survivors of Acute Lymphoblastic Leukemia Open
Background: Emerging treatment strategies have enhanced life expectancy for cancer patients, but late complications, including vaccine-preventable infections from diminished antibody titers, are common. This study evaluates viral vaccine i…
View article: Impacts of Hematopoietic Stem Cell Transplantation on Quality of Life and Behavioral Outcomes in Pediatric Patients with Leukemia and Thalassemia
Impacts of Hematopoietic Stem Cell Transplantation on Quality of Life and Behavioral Outcomes in Pediatric Patients with Leukemia and Thalassemia Open
Background: This study aimed to investigate the effects of allogeneic hematopoietic stem cell transplantation (HSCT) on quality of life and behavioral problems in children diagnosed with leukemia and β-thalassemia major, with a focus on po…
View article: Neurologic Toxicity in Children with Acute Lymphoblastic Leukemia
Neurologic Toxicity in Children with Acute Lymphoblastic Leukemia Open
Objective: The objective of this study was to evaluate the occurence of neurological complications and long-term neurological sequelae in children with acute lymphoblastic leukemia (ALL). These complications were examined in relation to de…
View article: <scp>BK</scp> Virus‐Related Haemorrhagic Cystitis in Non‐Transplanted Children With Leukaemia
<span>BK</span> Virus‐Related Haemorrhagic Cystitis in Non‐Transplanted Children With Leukaemia Open
Background Although it is well‐known in transplant recipients, BK virus (BKV)‐related haemorrhagic cystitis (HC) is an unexpected complication in children with leukaemia on standard chemotherapy. Methods This retrospective observational st…
View article: The importance of targeted next-generation sequencing based genomic profiling in the diagnosis of childhood acute myeloid leukemia: a single center experience
The importance of targeted next-generation sequencing based genomic profiling in the diagnosis of childhood acute myeloid leukemia: a single center experience Open
Background. The management of pediatric acute myeloid leukemia (AML) is based on the prognostic risk classification of initial leukemia. Targeted next-generation sequencing (NGS) is a reliable method used to identify recurrently mutated ge…
View article: The Effect of Iron Deficiency Anemia on Emergency Department Admission in Asthmatic Children
The Effect of Iron Deficiency Anemia on Emergency Department Admission in Asthmatic Children Open
Background Iron deficiency (ID) is the most common nutritional deficiency and cause of anemia in childhood. Iron deficiency anemia (IDA) is a common public health problem in Turkey as in the rest of the World. Asthma is a chronic inflammat…
View article: Blood component-associated acute transfusion reactions in pediatric patients: experience of a tertiary care hospital
Blood component-associated acute transfusion reactions in pediatric patients: experience of a tertiary care hospital Open
Within our hospital, pediatric hematology-oncology wards and the stem cell transplantation unit had the most frequent ATR reports; therefore, when transfusions are carried out, increased attention should be given to these units. Educating …
View article: ANTIBIOTIC LOCK THERAPY FOR PORT CATHETER-RELATED INFECTIONS OF CHILDREN WITH ACUTE LEUKEMIA
ANTIBIOTIC LOCK THERAPY FOR PORT CATHETER-RELATED INFECTIONS OF CHILDREN WITH ACUTE LEUKEMIA Open
Background: Port catheters facilitate the administration of chemotherapy, antibiotics, blood products, fluid and parenteral nutritional support to pediatric patients with hematological malignancies. However, as its use has become widesprea…
View article: Microbiologically Documented Infection-related Mortality in Children with Acute Leukemia: A Single-center Experience
Microbiologically Documented Infection-related Mortality in Children with Acute Leukemia: A Single-center Experience Open
Infections are a significant cause of morbidity and mortality of chemotherapy-induced neutropenia in children with acute leukemia. The aim of this study was to evaluate microbiologically documented infections (MDIs) during febrile neutrope…
View article: BK-VIRUS INFECTIONS IN PEDIATRIC LEUKEMIA PATIENTS DURING LEUKEMIA TREATMENT
BK-VIRUS INFECTIONS IN PEDIATRIC LEUKEMIA PATIENTS DURING LEUKEMIA TREATMENT Open
Objective: Polyoma BK virus (BKV) infection/reactivation is an important underlying condition that provokes hemorrhagic cystitis (HC) in hematopoietic stem cell transplantation (HSCT) recipients. However, BKV associated infections can rare…
View article: A NEXT-GENERATION SEQUENCING TEST FOR CONGENITAL NEUTROPENIA IN PEDIATRIC PATIENTS
A NEXT-GENERATION SEQUENCING TEST FOR CONGENITAL NEUTROPENIA IN PEDIATRIC PATIENTS Open
Objective: Congenital neutropenia (CN) is a rare inherited hematological disease and its phenotypic, histologic and molecular aspects are heterogeneous. Congenital neutropenia can manifest as isolated neutropenia or neutropenia with extra-…
View article: The severity of COVID-19 infection in children with leukemia
The severity of COVID-19 infection in children with leukemia Open
Aims: The coronavirus disease 2019 (COVID-19) has been the cause of a global health crisis since the end of 2019. The aim of this study was to evaluate the clinical findings and treatment results of COVID-19 disease in pediatric patients w…
View article: Evaluation of Leukemia and Solid Tumors in Refugee Children in Turkey: A Tertiary Center Experience
Evaluation of Leukemia and Solid Tumors in Refugee Children in Turkey: A Tertiary Center Experience Open
Cancer care is progressively became as a significant worldwide challenge. Wars can cause destructions and delays in cancer diagnosis and treatment of displaced people. Cancer cure rates need to be improved in indefensible populations such …
View article: A New Perspective for Potential Organ Damage Due to Iron-Mediated Oxidation in Thalassemia Major Patients
A New Perspective for Potential Organ Damage Due to Iron-Mediated Oxidation in Thalassemia Major Patients Open
Background: The aim of this study is to develop new perspectives to prevent or reduce potential organ damage due to iron-mediated oxidation in thalassemia major patients. Methods: Seventy patients were included in this study. Blood samples…
View article: The Effects of Vitamin D on Myocardial Function Demonstrated by Speckle-Tracking Echocardiography in Children with Beta Thalassemia
The Effects of Vitamin D on Myocardial Function Demonstrated by Speckle-Tracking Echocardiography in Children with Beta Thalassemia Open
Vitamin D deficiency is frequently observed and causes decreased contractility in thalassemic patients. In our study, we observed that our patients' cardiac functions had improved after vitamin D replacement therapy.
View article: Pyruvate kinase deficiency mimicking congenital dyserythropoietic anemia type I
Pyruvate kinase deficiency mimicking congenital dyserythropoietic anemia type I Open
Background. Pyruvate kinase (PK) deficiency is the most common enzyme abnormality in the glycolytic pathway. Here, we describe two siblings with PK deficiency that mimicked congenital dyserythropoietic anemia (CDA) type I. Case. The siblin…
View article: ‘Trying to catch up with life’: The expectations and views of adolescent survivors of childhood acute lymphoblastic leukaemia about long‐term follow‐up care: A qualitative research
‘Trying to catch up with life’: The expectations and views of adolescent survivors of childhood acute lymphoblastic leukaemia about long‐term follow‐up care: A qualitative research Open
Adolescent survivors mainly need support in terms of psychosocial aspects: self-esteem-body image, school, peer relations and social activities during follow-up. Identified barriers related to follow-up were school absence and not able to …
View article: The Effects of Vitamin D on Myocardial Function Demonstrated by Speckle Tracking Echocardiography in Children With Βeta Thalassemia
The Effects of Vitamin D on Myocardial Function Demonstrated by Speckle Tracking Echocardiography in Children With Βeta Thalassemia Open
Objective : β-thalassemia major is an inherited hemoglobin disorder resulting in chronic hemolytic anemia. Cardiac involvement is the main cause of death in patients. Speckle-tracking echocardiography is feasible method for the evaluation …
View article: Analysis of Hemorrhagic Cystitis and BK Viremia in Children after Hematopoietic Stem Cell Transplantation
Analysis of Hemorrhagic Cystitis and BK Viremia in Children after Hematopoietic Stem Cell Transplantation Open
Purpose: Hemorrhagic cystitis (HC) which occurs in 9%–31% of recipients after hematopoietic stem cell transplantation (HSCT) is an important cause of morbidity and mortality. Various treatment approaches have been applied for such as conse…
View article: COMPARABLE OUTCOMES OF ALLOGENEIC PERIPHERAL BLOOD VERSUS BONE MARROW HEMATOPOIETIC STEM CELL TRANSPLANTATION IN CHILDREN
COMPARABLE OUTCOMES OF ALLOGENEIC PERIPHERAL BLOOD VERSUS BONE MARROW HEMATOPOIETIC STEM CELL TRANSPLANTATION IN CHILDREN Open
Objective: Hematopoietic stem cell transplantation (HSCT) is used in many malignant and non-malignant diseases in pediatric patients. Peripheral blood (PB), bone marrow (BM) or cord blood can be used as a graft source. In this study, it wa…
View article: CHARACTERISTICS AND OUTCOME OF T(8;21)-POSITIVE CHILDHOOD ACUTE MYELOID LEUKEMIA: A SINGLE INSTITUTION'S EXPERIENCE
CHARACTERISTICS AND OUTCOME OF T(8;21)-POSITIVE CHILDHOOD ACUTE MYELOID LEUKEMIA: A SINGLE INSTITUTION'S EXPERIENCE Open
Objective: Compared with other cytogenetic acute myeloid leukemia (AML) groups, patients with core-binding factor AML (CBF-AML) are considered as a favorable AML risk group based on their high remission rate and survival probabilities. How…
View article: Evaluation of Malignant Liver Tumors in Pediatric Patients: A Single Center Experience
Evaluation of Malignant Liver Tumors in Pediatric Patients: A Single Center Experience Open
Amaç: Çocukluk çağında malign karaciğer tümörleri nadirdir.Hepatoblastom ve hepatoselüler karsinom en sık görülen