Ayelet Sivan
2025
Supplementary Figure 9 from PKCδ Germline Variants and Genetic Deletion in Mice Augment Antitumor Immunity through Regulation of Myeloid Cells
2025 • Kyle R. Cron, Ayelet Sivan, Keston Aquino-Michaels, Andrea Ziblat, Emily F. Higgs, Randy F. Sweis, Ruxandra Tonea, Seoho Lee, Thomas F. Gajewski
2025
Data from PKCδ Germline Variants and Genetic Deletion in Mice Augment Antitumor Immunity through Regulation of Myeloid Cells
2025 • Kyle R. Cron, Ayelet Sivan, Keston Aquino-Michaels, Andrea Ziblat, Emily F. Higgs, Randy F. Sweis, Ruxandra Tonea, Seoho Lee, Thomas F. Gajewski
2025
Supplementary Figure 5 from PKCδ Germline Variants and Genetic Deletion in Mice Augment Antitumor Immunity through Regulation of Myeloid Cells
2025 • Kyle R. Cron, Ayelet Sivan, Keston Aquino-Michaels, Andrea Ziblat, Emily F. Higgs, Randy F. Sweis, Ruxandra Tonea, Seoho Lee, Thomas F. Gajewski
2025
Supplementary Figure 6 from PKCδ Germline Variants and Genetic Deletion in Mice Augment Antitumor Immunity through Regulation of Myeloid Cells
2025 • Kyle R. Cron, Ayelet Sivan, Keston Aquino-Michaels, Andrea Ziblat, Emily F. Higgs, Randy F. Sweis, Ruxandra Tonea, Seoho Lee, Thomas F. Gajewski
2025
Supplementary Figure 1 from PKCδ Germline Variants and Genetic Deletion in Mice Augment Antitumor Immunity through Regulation of Myeloid Cells
2025 • Kyle R. Cron, Ayelet Sivan, Keston Aquino-Michaels, Andrea Ziblat, Emily F. Higgs, Randy F. Sweis, Ruxandra Tonea, Seoho Lee, Thomas F. Gajewski
Open Author Page
Exploring foci of
2025-04-02
Supplementary Figure 1 from PKCδ Germline Variants and Genetic Deletion in Mice Augment Antitumor Immunity through Regulation of Myeloid Cells
2025-04-02 • Kyle R. Cron, Ayelet Sivan, Keston Aquino-Michaels, Andrea Ziblat, Emily F. Higgs, Randy F. Sweis, Ruxandra Tonea, Seoho Lee, Thomas F. Gajewski
<p>Overview of the targeting strategy employed for creation of the <i>Prkcd</i> conditional knockout mice</p>
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Hello Muddah, Hello Fadduh (A Letter From Camp)
So Far From God
Tales From Planet Earth
Plan 9 From Outer Space
Javier Fernández (Figure Skater)
Away From Her
The Girl From Everywhere
The View From Saturday
Suicide Notes From Beautiful Girls
Open Article Page
Exploring foci of
2025-04-02
Supplementary Figure 9 from PKCδ Germline Variants and Genetic Deletion in Mice Augment Antitumor Immunity through Regulation of Myeloid Cells
2025-04-02 • Kyle R. Cron, Ayelet Sivan, Keston Aquino-Michaels, Andrea Ziblat, Emily F. Higgs, Randy F. Sweis, Ruxandra Tonea, Seoho Lee, Thomas F. Gajewski
<p>SNP alleles correlate with an M1/M2 gene signature score</p>
Open Article Page
Hello Muddah, Hello Fadduh (A Letter From Camp)
So Far From God
Tales From Planet Earth
Plan 9 From Outer Space
Javier Fernández (Figure Skater)
Away From Her
The Girl From Everywhere
The View From Saturday
Suicide Notes From Beautiful Girls
Open Article Page
Exploring foci of
2025-04-02
Data from PKCδ Germline Variants and Genetic Deletion in Mice Augment Antitumor Immunity through Regulation of Myeloid Cells
2025-04-02 • Kyle R. Cron, Ayelet Sivan, Keston Aquino-Michaels, Andrea Ziblat, Emily F. Higgs, Randy F. Sweis, Ruxandra Tonea, Seoho Lee, Thomas F. Gajewski
<div>Abstract<p>Based on the notion that hypomorphic germline genetic variants are linked to autoimmune diseases, we reasoned that novel targets for cancer immunotherapy might be identified through germline variants associated with greater T-cell infiltration into tumors. Here, we report that while investigating germline polymorphisms associated with a tumor immune gene signature, we identified protein kinase C delta (PKCδ) as a candidate. Genetic deletion of <i>Prkcd</i> in mice resulted i…
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Hello Muddah, Hello Fadduh (A Letter From Camp)
Computer Data Storage
So Far From God
Tales From Planet Earth
Tokenization (Data Security)
Plan 9 From Outer Space
Away From Her
The Girl From Everywhere
The View From Saturday
Open Article Page
Exploring foci of
2025-04-02
Supplementary Figure 5 from PKCδ Germline Variants and Genetic Deletion in Mice Augment Antitumor Immunity through Regulation of Myeloid Cells
2025-04-02 • Kyle R. Cron, Ayelet Sivan, Keston Aquino-Michaels, Andrea Ziblat, Emily F. Higgs, Randy F. Sweis, Ruxandra Tonea, Seoho Lee, Thomas F. Gajewski
<p>GSEA reveals many macrophage-related gene sets that are enriched in the C1qa DEG list.</p>
Open Article Page
Hello Muddah, Hello Fadduh (A Letter From Camp)
So Far From God
Tales From Planet Earth
Plan 9 From Outer Space
Javier Fernández (Figure Skater)
Away From Her
The Girl From Everywhere
The View From Saturday
Suicide Notes From Beautiful Girls
Open Article Page
Exploring foci of
2025-04-02
Supplementary Figure 6 from PKCδ Germline Variants and Genetic Deletion in Mice Augment Antitumor Immunity through Regulation of Myeloid Cells
2025-04-02 • Kyle R. Cron, Ayelet Sivan, Keston Aquino-Michaels, Andrea Ziblat, Emily F. Higgs, Randy F. Sweis, Ruxandra Tonea, Seoho Lee, Thomas F. Gajewski
<p>Hematopoietic loss of PKCδ via Vav1-iCre delays tumor growth and alters inflammatory gene expression in “2B4”Prkcdfl/fl founder.</p>
Open Article Page
Hello Muddah, Hello Fadduh (A Letter From Camp)
So Far From God
Tales From Planet Earth
Plan 9 From Outer Space
Javier Fernández (Figure Skater)
Away From Her
The Girl From Everywhere
The View From Saturday
Suicide Notes From Beautiful Girls
Open Article Page