Afshin Ehsan
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View article: INTEGRATING CANCER GENETICS WITH METASTATIC BIOMARKER DYNAMICS: MMP-2, AND MMP-9 IN BREAST CANCER PROGRESSION AND DISEASE MANAGEMENT
INTEGRATING CANCER GENETICS WITH METASTATIC BIOMARKER DYNAMICS: MMP-2, AND MMP-9 IN BREAST CANCER PROGRESSION AND DISEASE MANAGEMENT Open
Background: Breast cancer is one of the leading causes of cancer-related morbidity and mortality globally, with its metastatic nature contributing significantly to poor clinical outcomes. Identifying reliable plasma biomarkers associated w…
View article: Unusual Presentation of Anti-SAE 100 Myositis: Recurrent Pericardial Effusion and Respiratory Muscle Involvement in Absence of Cutaneous and Proximal Muscle Weakness
Unusual Presentation of Anti-SAE 100 Myositis: Recurrent Pericardial Effusion and Respiratory Muscle Involvement in Absence of Cutaneous and Proximal Muscle Weakness Open
Idiopathic inflammatory myopathies are a group of clinically heterogeneous autoimmune inflammatory muscular disorders characterized by muscular weakness and multisystem involvement. Antibodies against the small ubiquitin-like modifier acti…
View article: The Role of Preoperative Chronic Hypertension in Neurocognitive Decline after Cardiac Surgery: A Retrospective Cohort Study
The Role of Preoperative Chronic Hypertension in Neurocognitive Decline after Cardiac Surgery: A Retrospective Cohort Study Open
Chronic exposure to elevated preoperative systolic blood pressure may increase the risk of NCD. The contributing role of preoperative hypertension in NCD may be partly explained by reduced attenuation of oxidative stress, increased inflamm…
View article: Temporal trends of aortic valve replacement modalities by age group in the United-States 2015 - 2023
Temporal trends of aortic valve replacement modalities by age group in the United-States 2015 - 2023 Open
Background/Introduction Transcatheter aortic valve implantation (TAVI) has led to a paradigm shift in treating aortic stenosis (AS) across patients of all surgical-risk categories. To guide the clinical decision, the ACC/AHA guidelines rec…
View article: C-83 | Characteristics, Trends, and Outcomes of Intravascular Lithotripsy-Assisted Transfemoral Transcatheter Aortic Valve Replacement In the United States: A Nationwide Analysis from the Vizient Clinical Database
C-83 | Characteristics, Trends, and Outcomes of Intravascular Lithotripsy-Assisted Transfemoral Transcatheter Aortic Valve Replacement In the United States: A Nationwide Analysis from the Vizient Clinical Database Open
Transfemoral (TF) access is the preferred approach fortranscatheter aortic valve replacement (TAVR). Limited data exist regarding the role of intravascular lithotripsy to facilitate TF-TAVR (IVL-TAVR) in patients with iliofemoral periphera…
View article: Antineutrophil Cytoplasmic Antibody Vasculitis after Coronary Artery Bypass Grafting
Antineutrophil Cytoplasmic Antibody Vasculitis after Coronary Artery Bypass Grafting Open
Antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis is a group of rare autoimmune disorders associated with the presence of ANCA autoantibodies. We present the first reported case of acute ANCA‐associated vasculitis following …
View article: Enhanced Anomaly Detection in Ethereum: Unveiling and Classifying Threats With Machine Learning
Enhanced Anomaly Detection in Ethereum: Unveiling and Classifying Threats With Machine Learning Open
Blockchain has emerged as a groundbreaking security technology, playing a vital role in various industries such as banking, the Internet of Things (IoT), healthcare, education, and voting. However, the widespread adoption of this technolog…
View article: Hepatic and Renal Outcomes in Systemic Lupus Erythematosus Patients following Coronary Artery Bypass Grafting: A Study from the National Inpatient Sample
Hepatic and Renal Outcomes in Systemic Lupus Erythematosus Patients following Coronary Artery Bypass Grafting: A Study from the National Inpatient Sample Open
Background and Aim of the Study. While several studies have suggested a relationship between adverse postoperative outcomes and systemic lupus erythematosus (SLE) in major surgical settings, no study to date has explored postoperative outc…
View article: Cytogenetics Technologists and Workforce- Private and Academic Collaboration to Sustain Expertise as Formal Training Programs get curtailed
Cytogenetics Technologists and Workforce- Private and Academic Collaboration to Sustain Expertise as Formal Training Programs get curtailed Open
Introduction/Objective Cancer Cytogenetics (CG) and Fluorescence in-situ Hybridization (FISH) testing are essential parts of molecular genetics (MG) in clinical diagnosis for patients suffering from hematopoietic disorders. Even though MG …
View article: Next-Generation Sequencing Testing and Triaging of Bone Marrow Samples: Indications, Pre-authorization and Medical Necessity for Patient Care
Next-Generation Sequencing Testing and Triaging of Bone Marrow Samples: Indications, Pre-authorization and Medical Necessity for Patient Care Open
Introduction/Objective Bone marrow biopsy (BMBx) is an invasive procedure and samples are usually obtained for diagnosis, staging and prognosis of hematolymphoid disorders (HDs). Given the need for WHO and ICC classification of HDs; the Ne…
View article: GATA2 Mutation with Bone Marrow Failure. A Review of Ordering Next Generation Sequencing Testing while Triaging Bone Marrows in Patients with Cytopenias – Pathologists Challenge
GATA2 Mutation with Bone Marrow Failure. A Review of Ordering Next Generation Sequencing Testing while Triaging Bone Marrows in Patients with Cytopenias – Pathologists Challenge Open
Introduction/Objective GATA2 (germline) mutations are a cause of bone marrow (BM) failure in younger patients characterized by pancytopenia and hypoplastic BM with minimal or no dysplasia. These cases may have negative cytogenetic (CG)/FIS…
View article: Technical and Professional Components in Pathology Practices – Business and Educational Opportunities for Community Based Pathologists
Technical and Professional Components in Pathology Practices – Business and Educational Opportunities for Community Based Pathologists Open
Introduction/Objective Community based Pathologists (CBPs) are challenged by limited resources, decreasing revenue, continuous learning, workload burnout and acquisition by corporate health care groups. Pathology residency programs (PRPs) …
View article: Pathologists Shortage in United States of America (USA) - How Academic Centers and Private Laboratories Can Play an Effective Role in Recruiting Qualified Future Pathology Residents from Pool of United States (US) and International Medical Graduates (IMGs)
Pathologists Shortage in United States of America (USA) - How Academic Centers and Private Laboratories Can Play an Effective Role in Recruiting Qualified Future Pathology Residents from Pool of United States (US) and International Medical Graduates (IMGs) Open
Introduction/Objective Pathology training (PT) in the US requires 4 years of AP/CP training. Only 2% of any medical school class (US or IMGs) enter Pathology. However, among practicing pathologists, an estimated 20 to 30% are IMGs that are…
View article: Lymph Nodes Triaging by General Surgical Pathologists – Flow Cytometry or Immunohistochemistry or Both?
Lymph Nodes Triaging by General Surgical Pathologists – Flow Cytometry or Immunohistochemistry or Both? Open
Introduction/Objective The diagnosis of lymphoma has become complex due to existing WHO/ICC classifications. Triaging Lymph Nodes (LN) is an important first step in making the correct and precise diagnosis in a timely and cost- effective m…
View article: Pre-Accessioning in Anatomic Pathology – Utilizing a Cloud-Based Laboratory Information System Reducing Error in Anatomic Pathology and Improving Patient Safety
Pre-Accessioning in Anatomic Pathology – Utilizing a Cloud-Based Laboratory Information System Reducing Error in Anatomic Pathology and Improving Patient Safety Open
Introduction/Objective Typical workflow in Anatomic Pathology (AP) starts from accessioning of cases to sign out. Most Laboratory Information System (LIS) follow this cycle of sample tracking. However, at certain times, either samples are …
View article: How youth engagement can break surgery out of its silo in global health
How youth engagement can break surgery out of its silo in global health Open
info:eu-repo/semantics/published
View article: Transcatheter Aortic Valve Replacement and Impact of Subclinical Leaflet Thrombosis in Low-Risk Patients: LRT Trial 4-Year Outcomes
Transcatheter Aortic Valve Replacement and Impact of Subclinical Leaflet Thrombosis in Low-Risk Patients: LRT Trial 4-Year Outcomes Open
Background: The LRT trial (Low-Risk Transcatheter Aortic Valve Replacement [TAVR]) demonstrated the safety and feasibility of TAVR in low-risk patients, with excellent 1- and 2-year outcomes. The objective of the current study is to provid…