Ayman Z. Elsamanoudy
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View article: The interplay between nutrigenomics and low-carbohydrate ketogenic diets in personalized healthcare
The interplay between nutrigenomics and low-carbohydrate ketogenic diets in personalized healthcare Open
The field of nutrigenomics explores the interaction between diet and gene expression, examining how nutrients function as signaling molecules that influence cellular processes, protein synthesis, and metabolite production. This discipline …
View article: Six-step approach for developing customized GPT in medical education
Six-step approach for developing customized GPT in medical education Open
Incorporating generative AI into medical education is important nowadays. This study employs a six-step approach to establish guidelines for creating customized GPT models in this field. Following structured steps, we developed customized …
View article: Evaluation of modified essay questions (MEQs) as an assessment tool in third-year medical students’ modular summative assessment
Evaluation of modified essay questions (MEQs) as an assessment tool in third-year medical students’ modular summative assessment Open
Implementing case-based MEQs and MCQs in the summative assessment of medical curriculum favored discrimination between high and low scorers, minimized chances for students' guessing and fostered deep learning and analytical comprehension o…
View article: The role of low-carbohydrate, high-fat diet in modulating autophagy and endoplasmic reticulum stress in aortic endothelial dysfunction of metabolic syndrome animal model
The role of low-carbohydrate, high-fat diet in modulating autophagy and endoplasmic reticulum stress in aortic endothelial dysfunction of metabolic syndrome animal model Open
Background Endothelial dysfunction (ED) is induced by insulin resistance, mediated by endoplasmic reticulum (ER) stress and disturbed autophagy. This study investigates the protective role of a low-carbohydrate, high-fat (LCHF) diet on ED,…
View article: Exploring the role of noncoding RNAs in cancer diagnosis, prognosis, and precision medicine
Exploring the role of noncoding RNAs in cancer diagnosis, prognosis, and precision medicine Open
View article: Review of: "Influence of Meta-cognition, Self-efficacy, and Self-regulated Learning on Students’ Achievement in Biology in Ibadan, Nigeria"
Review of: "Influence of Meta-cognition, Self-efficacy, and Self-regulated Learning on Students’ Achievement in Biology in Ibadan, Nigeria" Open
View article: Review of: "Implementing Simulation Software to Develop Virtual Experiments in Undergraduate Chemical Engineering Education"
Review of: "Implementing Simulation Software to Develop Virtual Experiments in Undergraduate Chemical Engineering Education" Open
View article: Introducing Group Open-Book Exams as a Learning and Assessment Strategy in the Clinical Biochemistry Course for Medical Students
Introducing Group Open-Book Exams as a Learning and Assessment Strategy in the Clinical Biochemistry Course for Medical Students Open
A combined model of modified TBL and OBE is a successful learning and assessment strategy in clinical biochemistry for medical students.
View article: Molecular Study of the Protective Effect of a Low-Carbohydrate, High-Fat Diet against Brain Insulin Resistance in an Animal Model of Metabolic Syndrome
Molecular Study of the Protective Effect of a Low-Carbohydrate, High-Fat Diet against Brain Insulin Resistance in an Animal Model of Metabolic Syndrome Open
Brain insulin resistance is linked to metabolic syndrome (MetS). A low-carbohydrate, high-fat (LCHF) diet has been proposed to have a protective effect. Therefore, this study aimed to investigate the brain insulin resistance markers in a r…
View article: The Effect of Chronic Laxative Use on Lipid Profile and HbA1c: A Hospital-Based Retrospective Study
The Effect of Chronic Laxative Use on Lipid Profile and HbA1c: A Hospital-Based Retrospective Study Open
View article: Insulin Resistance and Hypertension: Mechanisms Involved and Modifying Factors for Effective Glucose Control
Insulin Resistance and Hypertension: Mechanisms Involved and Modifying Factors for Effective Glucose Control Open
Factors such as aging, an unhealthy lifestyle with decreased physical activity, snacking, a standard Western diet, and smoking contribute to raising blood pressure to a dangerous level, increasing the risk of coronary artery disease and he…
View article: Association between laboratory markers and Covid-19 disease severity and outcome: a retrospective cohort study in Saudi Arabia
Association between laboratory markers and Covid-19 disease severity and outcome: a retrospective cohort study in Saudi Arabia Open
Introduction In Saudi Arabia, limited studies have evaluated factors including epidemiologic, clinical, and laboratory findings that are associated with COVID-19 disease. The aim of this paper was to identify laboratory parameters used in …
View article: The Possible Effect of the Long-Term Use of Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) on Hba1c and Lipid Profile in Type 2 Diabetes Mellitus: A Retrospective Study in KAUH, Jeddah, Saudi Arabia
The Possible Effect of the Long-Term Use of Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) on Hba1c and Lipid Profile in Type 2 Diabetes Mellitus: A Retrospective Study in KAUH, Jeddah, Saudi Arabia Open
(1) Background: Type 2 diabetes (T2DM) is a chronic metabolic disease with serious health complications. T2DM is associated with many chronic illnesses, including kidney failure, cardiovascular diseases (CVD), vision loss, and other relate…
View article: Prevalence of Gastroesophageal Reflux Disease (GERD) Among Electronic Cigarette-Smoking University Students in Jeddah, Saudi Arabia
Prevalence of Gastroesophageal Reflux Disease (GERD) Among Electronic Cigarette-Smoking University Students in Jeddah, Saudi Arabia Open
View article: Discrimination Power of Short Essay Questions Versus Multiple Choice Questions as an Assessment Tool in Clinical Biochemistry
Discrimination Power of Short Essay Questions Versus Multiple Choice Questions as an Assessment Tool in Clinical Biochemistry Open
Assessment is fundamental to the educational process. Multiple choice questions (MCQs) and short essay questions (SEQs) are the most widely used assessment method in medical school. The current study evaluated the discriminating value of S…
View article: Low-Carbohydrate High-Fat Diet: A SWOC Analysis
Low-Carbohydrate High-Fat Diet: A SWOC Analysis Open
Insulin resistance (IR) plays a role in the pathogenesis of many diseases, such as type 2 diabetes mellitus, cardiovascular disease, non-alcoholic fatty liver disease, obesity, and neurodegenerative diseases, including Alzheimer’s disease.…
View article: Retraction Note: Does immediate postpartum curettage of the endometrium accelerate recovery from preeclampsia–eclampsia? A randomized controlled trial
Retraction Note: Does immediate postpartum curettage of the endometrium accelerate recovery from preeclampsia–eclampsia? A randomized controlled trial Open
View article: The impact of medical knowledge on modifying the Lifestyle among medical students of King Abdulaziz University clinical years
The impact of medical knowledge on modifying the Lifestyle among medical students of King Abdulaziz University clinical years Open
Background and aim of the work: It has been understood that students at medical schools are more mindful of the value of living a healthy lifestyle than others.So, the current study aims to investigate the medical Knowledge of a healthy li…
View article: Endoplasmic reticulum stress and mitochondrial injury are critical molecular drivers of AlCl3-induced testicular and epididymal distortion and dysfunction: protective role of taurine
Endoplasmic reticulum stress and mitochondrial injury are critical molecular drivers of AlCl3-induced testicular and epididymal distortion and dysfunction: protective role of taurine Open
Aluminum, the third most plentiful metal in the Earth’s crust, has potential for human exposure and harm. Oxidative stress plays an essential role in producing male infertility by inducing defects in sperm functions. We aimed to investigat…
View article: Modulation of Dyslipidemia Markers Apo B/Apo A and Triglycerides/HDL-Cholesterol Ratios by Low-Carbohydrate High-Fat Diet in a Rat Model of Metabolic Syndrome
Modulation of Dyslipidemia Markers Apo B/Apo A and Triglycerides/HDL-Cholesterol Ratios by Low-Carbohydrate High-Fat Diet in a Rat Model of Metabolic Syndrome Open
Metabolic syndrome (MetS) risks cardiovascular diseases due to its associated Dyslipidemia. It is proposed that a low-carbohydrate, high-fat (LCHF) diet positively ameliorates the MetS and reverses insulin resistance. Therefore, we aimed t…
View article: Evaluating Online Learning Strategy and Assessment Methods in the Course of Human Biology for the Preparatory Year Medical Students During COVID-19 Pandemic Lockdown
Evaluating Online Learning Strategy and Assessment Methods in the Course of Human Biology for the Preparatory Year Medical Students During COVID-19 Pandemic Lockdown Open
Since the lockdown caused by the COVID-19 crisis, there has been insufficient reporting regarding the evaluation of students’ performance in biology courses in medical schools. This study is designed to evaluate the online learning strateg…
View article: Integrative system biology and mathematical modeling of genetic networks identifies shared biomarkers for obesity and diabetes
Integrative system biology and mathematical modeling of genetic networks identifies shared biomarkers for obesity and diabetes Open
Obesity and type 2 and diabetes mellitus (T2D) are two dual epidemics whose shared genetic pathological mechanisms are still far from being fully understood. Therefore, this study is aimed at discovering key genes, molecular mechanisms, a…
View article: Evaluation of Endothelial Dysfunction and Autophagy in Fibromyalgia-Related Vascular and Cerebral Cortical Changes and the Ameliorative Effect of Fisetin
Evaluation of Endothelial Dysfunction and Autophagy in Fibromyalgia-Related Vascular and Cerebral Cortical Changes and the Ameliorative Effect of Fisetin Open
Fibromyalgia (FM) is a common chronic pain syndrome that affects 1% to 5% of the population. We aimed to investigate the role of endothelial dysfunction and autophagy in fibromyalgia-related vascular and cerebral cortical changes in a rese…
View article: The Interplay of Vitamin D Deficiency and Cellular Senescence in The Pathogenesis of Obesity-Related Co-Morbidities
The Interplay of Vitamin D Deficiency and Cellular Senescence in The Pathogenesis of Obesity-Related Co-Morbidities Open
This scoping review aims to clarify the interplay between obesity, vitamin D deficiency, cellular senescence, and obesity-related metabolic consequences, mainly subclinical atherosclerosis, and non-alcoholic fatty liver disease (NAFLD). Ob…
View article: Project-Based Learning Strategy for Teaching Molecular Biology: A Study of Students’ Perceptions
Project-Based Learning Strategy for Teaching Molecular Biology: A Study of Students’ Perceptions Open
This current study aims to analyse students’ perceptions regarding implementing project-based learning (PjBL) in teaching a molecular biology course to second-year pharmacy students at King Abdulaziz University as a sort of active student-…
View article: Short versus long video-based lectures as a tool for faculty development during COVID-19 pandemic
Short versus long video-based lectures as a tool for faculty development during COVID-19 pandemic Open
With emerge of the COVID-19 pandemic, video-based lectures (VBLs) was widely used as an effective online faculty development tool. VBLs varies from short videos (5-minute) to the long one (1-2 hours). So, the current study aims to evaluate…
View article: Cellular Senescence and Vitamin D Deficiency Play a Role in the Pathogenesis of Obesity-Associated Subclinical Atherosclerosis: Study of the Potential Protective Role of Vitamin D Supplementation
Cellular Senescence and Vitamin D Deficiency Play a Role in the Pathogenesis of Obesity-Associated Subclinical Atherosclerosis: Study of the Potential Protective Role of Vitamin D Supplementation Open
The exact link between obesity, vitamin D deficiency, and their relation to cellular senescence in the pathogenesis of subclinical atherosclerosis is still under debate. Therefore, the current study aims to verify the possible role of vita…
View article: Relationship between admission criteria and academic performance in basic science courses in health science colleges in KAU
Relationship between admission criteria and academic performance in basic science courses in health science colleges in KAU Open
Background At King Abdulaziz University, medical and health science schools depend on admission exams (aptitude and achievement) and preparatory year scores in their students’ selection. However, with the growing number of applicants and t…
View article: Relationship between Admission Criteria and Academic Performance in Basic Science Courses in Health Science Colleges in KAU
Relationship between Admission Criteria and Academic Performance in Basic Science Courses in Health Science Colleges in KAU Open
Background At King Abdulaziz University, medical and health science schools depend on admission exams (aptitude and achievement) and preparatory year scores in their students’ selection. However, with the growing number of applicants and t…
View article: Relationship between Admission Criteria and Academic Performance in Basic Science Courses in Health Science Colleges in KAU
Relationship between Admission Criteria and Academic Performance in Basic Science Courses in Health Science Colleges in KAU Open
Background: In King Abdulaziz University, medical and health science schools depend on admission exams (Aptitude and Achievement) and Preparatory year scores in their students’ selection. However, with the growing number of applicants and …