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View article: Intestinal Ultrasound: Advancing Towards Broader Adoption—Insights from a National Survey in Turkey
Intestinal Ultrasound: Advancing Towards Broader Adoption—Insights from a National Survey in Turkey Open
Objective: Intestinal ultrasound (IUS) is increasingly valued as a noninvasive tool for inflammatory bowel disease (IBD) management, offering real-time, radiation-free assessment of bowel wall thickness, vascularity, and complications. Whi…
View article: INFUSION FROM C. COGGYGRIA SCOP. LEAVES ON THE HEPATIC OXIDATIVE STRESS IN MICE WITH DEXTRAN SODIUM SULPHATE (DSS)-INDUCED ULCERATIVE COLITIS
INFUSION FROM C. COGGYGRIA SCOP. LEAVES ON THE HEPATIC OXIDATIVE STRESS IN MICE WITH DEXTRAN SODIUM SULPHATE (DSS)-INDUCED ULCERATIVE COLITIS Open
Objective: Since free radicals play a crucial role in ulcerative colitis (UC)- assotiated liver manifestations, antioxidants of plant origin have been proposed as potential therapeutic agents to counteract liver damage. This study aimed to…
View article: A Classification for Gastric Outlet Obstruction in Childhood: Extending Beyond Infantile Hypertrophic Pyloric Stenosis
A Classification for Gastric Outlet Obstruction in Childhood: Extending Beyond Infantile Hypertrophic Pyloric Stenosis Open
This is the first and largest study of GOO in children. From the perspective of pediatric gastroenterology, new diseases will be addressed, and definitions will be highlighted with our classification for GOO in childhood.
View article: In vitro inhibitory potential of Amaranthus lividus L. against therapeutic target enzymes
In vitro inhibitory potential of Amaranthus lividus L. against therapeutic target enzymes Open
Background and Aims: The search for new enzyme inhibitors in plants is attractive because they can be used as drugs in the treatment of various diseases. Amaranthus spp. (Amaranthaceae) includes about 70 different species, some of which ar…
View article: Identification of AKT1/β-catenin mutations conferring cetuximab and chemotherapeutic drug resistance in colorectal cancer treatment
Identification of AKT1/β-catenin mutations conferring cetuximab and chemotherapeutic drug resistance in colorectal cancer treatment Open
In anticancer therapy, the effectiveness of therapeutics is limited by mutations causing drug resistance. KRAS mutations are the only determinant for cetuximab resistance in patients with colorectal cancer (CRC). However, cetuximab treatme…
View article: Comparison Of Conductivity, Total Hardness and Free Chlorine Levels In Waters Given To Networks With The Blue Tunnel Drinking Water Project With The Values Of 2016 In Meram District Of Konya
Comparison Of Conductivity, Total Hardness and Free Chlorine Levels In Waters Given To Networks With The Blue Tunnel Drinking Water Project With The Values Of 2016 In Meram District Of Konya Open
Objective: "Access to clean drinking water" is an essential issue for every individual and is the most important phenomenon of human rights.The criteria of clean and usable water are regulated in our country with the "Regulation on Water f…
View article: Effects of Microalga (Chlorella vulgaris Beijerinck) on Seconder Metabolites and Antioxidative Defense System Improve Plant Growth and Salt Tolerance in Guar [Cyamopsis tetragonoloba (L.) Taub.]
Effects of Microalga (Chlorella vulgaris Beijerinck) on Seconder Metabolites and Antioxidative Defense System Improve Plant Growth and Salt Tolerance in Guar [Cyamopsis tetragonoloba (L.) Taub.] Open
Microalgae, such as Chlorella vulgaris, are beneficial microscopic organisms that may result in a plant having improved nutrient uptake, growth and abiotic stress tolerance. In this study, the application of microalga significantly increas…
View article: PPARγ Pro12Ala and C161T polymorphisms, but not PPARα L162V, are associated with osteoporosis risk in Turkish postmenopausal women
PPARγ Pro12Ala and C161T polymorphisms, but not PPARα L162V, are associated with osteoporosis risk in Turkish postmenopausal women Open
DOI : 10.26650/IstanbulJPharm.2019.18005Stimulation of peroxisomeproliferator-activated receptors (PPARs) causes mesenchymal stem cells of thehuman bone marrow differentiate into adipocytes instead of osteoblasts leadingto a decreased numb…
View article: In vitro Antidiabetic Activities of Two Sorbus Species
In vitro Antidiabetic Activities of Two Sorbus Species Open
Fruitsof several Sorbus species (Rosaceace) are used both in traditional medicine asantidiabetic, antiinflammatory, diuretic, vasoprotective and in foods. In thisstudy, in vitro antidiabetic activities of water extracts of Sorbus aucuparia…
View article: The protective effect of an aqueous extract from <i>Smilax excelsa</i> l. against carbon tetrachloride-induced liver injury in rats
The protective effect of an aqueous extract from <i>Smilax excelsa</i> l. against carbon tetrachloride-induced liver injury in rats Open
Background: Because reactive oxygen species (ros) contribute to the pathogenesis of various acute and chronic liver diseases, dietary antioxidants and drugs from herbal origins have been proved to be beneficial as therapeutic agents in rev…
View article: THE PROTECTIVE EFFECT OF AN AQUEOUS EXTRACT FROM SMILAX EXCELSA L. AGAINST CARBON TETRACHLORIDE-INDUCED LIVER INJURY IN RATS
THE PROTECTIVE EFFECT OF AN AQUEOUS EXTRACT FROM SMILAX EXCELSA L. AGAINST CARBON TETRACHLORIDE-INDUCED LIVER INJURY IN RATS Open
Background: Because reactive oxygen species (ros) contribute to the pathogenesis of various acute and chronic liver diseases,
dietary antioxidants and drugs from herbal origins have been proved to be beneficial as therapeutic agents in re…