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View article: The LAST mile: Evaluating genetic biocontrol as a supplemental tool for eradicating invasive rodents on islands
The LAST mile: Evaluating genetic biocontrol as a supplemental tool for eradicating invasive rodents on islands Open
Invasive rodents cause severe ecosystem degradation on islands and can be challenging to eradicate. Current best-practices rely heavily on the application of toxic oral baits and have led to successful eradications and remarkable recoverie…
View article: Evaluating the potential of a new murine gene drive for pre-emptive mouse plague control
Evaluating the potential of a new murine gene drive for pre-emptive mouse plague control Open
Rodent outbreaks have significant ecological, agricultural and economic impacts around the world. Although they can occur with increasing frequency in some parts of the world, current management practices remain ineffective. Gene drives, w…
View article: Maximising Eradication Potential of Rat Gene Drives Using a Two‐Target Homing Rescue Strategy: Spatial Modelling of Empirical Data
Maximising Eradication Potential of Rat Gene Drives Using a Two‐Target Homing Rescue Strategy: Spatial Modelling of Empirical Data Open
Gene drives are genetic elements with positively biased transmission and may be useful tools to suppress mammalian pests that threaten biodiversity worldwide. While gene drives are progressing in mice, less is known about their potential f…
View article: Leveraging a natural murine meiotic drive to suppress invasive populations
Leveraging a natural murine meiotic drive to suppress invasive populations Open
Invasive rodents are a major cause of environmental damage and biodiversity loss, particularly on islands. Unlike insects, genetic biocontrol strategies including population-suppressing gene drives with biased inheritance have not been dev…
View article: Scalability of genetic biocontrols for eradicating invasive alien mammals
Scalability of genetic biocontrols for eradicating invasive alien mammals Open
CRISPR-based gene drives offer novel solutions for controlling invasive alien species, which could ultimately extend eradication efforts to continental scales. Gene drives for suppressing invasive alien vertebrates are now under developmen…
View article: Leveraging a natural murine meiotic drive to suppress invasive populations
Leveraging a natural murine meiotic drive to suppress invasive populations Open
Invasive rodents, including house mice, are a major cause of environmental damage and biodiversity loss, particularly in island ecosystems. Eradication can be achieved through the distribution of rodenticide, but this approach is expensive…
View article: Gene drives for vertebrate pest control: Realistic spatial modelling of eradication probabilities and times for island mouse populations
Gene drives for vertebrate pest control: Realistic spatial modelling of eradication probabilities and times for island mouse populations Open
Invasive alien species continue to threaten global biodiversity. CRISPR‐based gene drives, which can theoretically spread through populations despite imparting a fitness cost, could be used to suppress or eradicate pest populations. We dev…
View article: Archaeogenetics of Late Iron Age Çemialo Sırtı, Batman: Investigating maternal genetic continuity in north Mesopotamia since the Neolithic
Archaeogenetics of Late Iron Age Çemialo Sırtı, Batman: Investigating maternal genetic continuity in north Mesopotamia since the Neolithic Open
Objectives North Mesopotamia has witnessed dramatic social change during the Holocene, but the impact of these events on its demographic history is poorly understood. Here, we study this question by analysing genetic data from the recently…
View article: Archaeogenetics of Late Iron Age Çemialo Sırtı, Batman: Investigating maternal genetic continuity in North Mesopotamia since the Neolithic
Archaeogenetics of Late Iron Age Çemialo Sırtı, Batman: Investigating maternal genetic continuity in North Mesopotamia since the Neolithic Open
North Mesopotamia has witnessed dramatic political and social change since the Bronze Age, but the impact of these events on its demographic history is little understood. Here we study this question by analysing the recently excavated Late…