Muhammad A. Saeed
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View article: Discursive Strategies in Imran Khan’s Address to the United Nations General Assembly: Ideological Square Model Perspective
Discursive Strategies in Imran Khan’s Address to the United Nations General Assembly: Ideological Square Model Perspective Open
Critical discourse analysis unearths the ideologies, beliefs, and principles embedded in spoken and written discourse. Imran Khan’s addresses to national and international forums gained the attention of the discourse analysts. The current …
View article: Antioxidant Potential Calotropis Procera leaves, flowers, and latex, Zanthoxylum Armatum Dried Seeds, and Syzygium Aromaticum Dried Flower Buds
Antioxidant Potential Calotropis Procera leaves, flowers, and latex, Zanthoxylum Armatum Dried Seeds, and Syzygium Aromaticum Dried Flower Buds Open
Objectives: This study evaluates the antioxidant potential of Calotropis procera leaves, flowers, and latex, Zanthoxylum armatum dried seeds, and Syzygium aromaticum dried flower buds. Methodology: The extracts were prepared using methanol…
View article: Protease-activated receptor 1 in the pathogenesis of cystic fibrosis
Protease-activated receptor 1 in the pathogenesis of cystic fibrosis Open
Background The most common cause of death in those with cystic fibrosis (CF) is respiratory failure due to bronchiectasis resulting from repeated cycles of respiratory infection and inflammation. Protease-activated receptor 1 (PAR1) is a c…
View article: Figure S4 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S4 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
IL-15 treatment of sip-T significantly improves their cytotoxicity (determined by incucyte) against prostate tumors
View article: Figure S12 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S12 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
Correlation plots between clinical outcomes and sip-T subsets
View article: Figure S2 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S2 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
CyTOF analysis of various immune checkpoint molecules in sip-T subsets
View article: Figure S4 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S4 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
IL-15 treatment of sip-T significantly improves their cytotoxicity (determined by incucyte) against prostate tumors
View article: Figure S7 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S7 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
IL-15 significantly improves activation of sip-T in peripheral blood in vivo
View article: Figure S9 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S9 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
IL-15 does not alter CD54 expression in sip-T in vivo
View article: Data from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Data from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
Sipuleucel-T (sip-T) is the only FDA-approved autologous cellular immunotherapy for metastatic castration-resistant prostate cancer (mCRPC). To elucidate parameters of the response profile to this therapy, we report high-dimensional analys…
View article: Supplementary Tables 1-7 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Supplementary Tables 1-7 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
Supplementary Tables 1-7
View article: Supplementary Tables 1-7 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Supplementary Tables 1-7 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
Supplementary Tables 1-7
View article: Figure S3 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S3 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
IL-15 dose response in sipuleucel-T
View article: Figure S10 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S10 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
Correlation plots between PSA and sip-T subsets
View article: Figure S11 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S11 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
Correlation plots between overall survival and sip-T subsets
View article: Figure S6 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S6 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
CD8+ T-cell and CD56+ NK/T cells are the primary source of IL-15-mediated enhancement of sip-T efficacy
View article: Figure S9 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S9 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
IL-15 does not alter CD54 expression in sip-T in vivo
View article: Figure S3 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S3 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
IL-15 dose response in sipuleucel-T
View article: Data from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Data from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
Sipuleucel-T (sip-T) is the only FDA-approved autologous cellular immunotherapy for metastatic castration-resistant prostate cancer (mCRPC). To elucidate parameters of the response profile to this therapy, we report high-dimensional analys…
View article: Figure S1 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S1 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
Swimmer plots and PSA levels
View article: Figure S12 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S12 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
Correlation plots between clinical outcomes and sip-T subsets
View article: Figure S5 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S5 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
IL-15 expands antigen-specific T-cell subsets of sip-T
View article: Figure S8 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S8 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
IL-15 significantly improves sip-T mediated suppression of tumor growth in vivo
View article: Figure S11 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S11 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
Correlation plots between overall survival and sip-T subsets
View article: Figure S2 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S2 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
CyTOF analysis of various immune checkpoint molecules in sip-T subsets
View article: Figure S6 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S6 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
CD8+ T-cell and CD56+ NK/T cells are the primary source of IL-15-mediated enhancement of sip-T efficacy
View article: Figure S5 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance
Figure S5 from High-Dimensional Analyses Reveal IL15 Enhances Activation of Sipuleucel-T Lymphocyte Subsets and Reverses Immunoresistance Open
IL-15 expands antigen-specific T-cell subsets of sip-T