Gamal Abdelaziz
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View article: Wound healing treatment of local insulin injection with topical chitosan/ Zinc oxide nanocomposite membrane in diabetic rats model
Wound healing treatment of local insulin injection with topical chitosan/ Zinc oxide nanocomposite membrane in diabetic rats model Open
Diabetes put off healing method as it impairs every section of wound restoration i.e., hemostasis, irritation, proliferation, and remodeling section.Insulin and a natural polymer of chitosan (CS) can potentially repair the integrity of bro…
View article: Composite Nanoarchitectonics of Magnetic Silicon Dioxide-Modified Chitosan for Doxorubicin Delivery and In Vitro Cytotoxicity Assay
Composite Nanoarchitectonics of Magnetic Silicon Dioxide-Modified Chitosan for Doxorubicin Delivery and In Vitro Cytotoxicity Assay Open
Developing drug delivery carriers for highly selective, controlled, and sustained release of the anti-cancer drugs is one of the crucial issues in the cancer strive. We herein report the synthesis of Fe 3 O 4 (M) and SiO 2 (S) nanoparticle…
View article: Wound healing acceleration using topical chitosan/ Zinc oxide nanocomposite membrane and local insulin injection in diabetic rats via modulation of genes expression targeting angiogenesis
Wound healing acceleration using topical chitosan/ Zinc oxide nanocomposite membrane and local insulin injection in diabetic rats via modulation of genes expression targeting angiogenesis Open
Diabetic wounds regularly take a longer time to heal than wounds in healthy animals.Chitosan (CS) interacts with many cellular processes and it elevates the necessary expression of growth factors in wound healing.The topical utility of zin…
View article: Wounds healing activities of topical chitosan/ Zinc oxide nanocomposite membrane and local insulin injection in diabetic rats through activation of growth factors and suppression of matrix metalloproteinase expressions
Wounds healing activities of topical chitosan/ Zinc oxide nanocomposite membrane and local insulin injection in diabetic rats through activation of growth factors and suppression of matrix metalloproteinase expressions Open
Diabetes mellitus causes impaired wound healing. In this study the potential wounds healing activities of topical chitosan/ Zinc oxide nanocomposite membrane and local insulin injection in diabetic rats were evaluated. Diabetes was induced…
View article: Proposed therapies and vaccine developing for COVID-19 (SARS CoV-2)
Proposed therapies and vaccine developing for COVID-19 (SARS CoV-2) Open
COVID-19 or Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the third spillover of animal coronavirus to humans, resulting in a major respiratory epidemic in less than two decades. In March, 2020 the World Health Organizat…
View article: Applying radiolabeled novel recombinant insulin via 99mTc for ensuring native like action by in vivo biodistribution in mice.
Applying radiolabeled novel recombinant insulin via 99mTc for ensuring native like action by in vivo biodistribution in mice. Open
Val d'Essonne (UEVE)In order to study functionality and pharmacodynamics of any important biological molecule such hormones and enzymes, it takes a lot of time and complexed stratigies to do that.Here we study the incidence of new recombin…
View article: Recombinant human insulin as a solid tumor potential imaging agent: Radio-synthesis and biological evaluation
Recombinant human insulin as a solid tumor potential imaging agent: Radio-synthesis and biological evaluation Open
The aim of this study was to synthesis an imaging agent for tumor targeting. New recombinant insulin analogue was successfully produced from E. coli by recombinant DNA technique, and was well labeled with Technetium-99m with a high radioch…