Azmil H. Abdul‐Rahim
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View article: Stroke–heart syndrome and risk of incident dementia among patients with first‐ever ischemic stroke: A territory‐wide population‐based cohort study
Stroke–heart syndrome and risk of incident dementia among patients with first‐ever ischemic stroke: A territory‐wide population‐based cohort study Open
INTRODUCTION The risk of dementia in patients with ischemic stroke and early cardiovascular complications (i.e., stroke–heart syndrome [SHS]) remains underexplored. METHODS Patients with first‐ever ischemic stroke in Hong Kong between 2005…
View article: Intracranial arterial calcification as a marker of stroke risk and worse stroke outcomes in adults: A systematic review and meta-analysis
Intracranial arterial calcification as a marker of stroke risk and worse stroke outcomes in adults: A systematic review and meta-analysis Open
Background: Intracranial arterial calcification (ICAC) is common, but data on its impact on future stroke risk and outcomes remain limited. We conducted a systematic review and meta-analysis to investigate the association of ICAC with stro…
View article: Integrated Care Using the ABC<sub>stroke</sub> Pathway Improves Cardiovascular Outcomes and Survival in Patients with First-Ever Ischaemic Stroke
Integrated Care Using the ABC<sub>stroke</sub> Pathway Improves Cardiovascular Outcomes and Survival in Patients with First-Ever Ischaemic Stroke Open
Background: A recent position paper of the European Society of Cardiology Council on Stroke proposed an integrated ABCstroke pathway to optimise post-stroke management. We evaluated the impact of ABCstroke pathway adherence on post-stroke …
View article: Cardiovascular risk in multiple sclerosis: exploring the role of vitamin D - insights from the Cardio-MS project
Cardiovascular risk in multiple sclerosis: exploring the role of vitamin D - insights from the Cardio-MS project Open
Background People with multiple sclerosis (pwMS) face elevated cardiovascular disease (CVD) risk. While traditional CVD risk factors are established, their impact on major adverse cardiovascular events (MACE) in pwMS is underexplored. Addi…
View article: “Better Handshake Together”: 3 years in interdisciplinary approach of endoscopic dacryocystorhinostomy
“Better Handshake Together”: 3 years in interdisciplinary approach of endoscopic dacryocystorhinostomy Open
Background Dacryocystorhinostomy (DCR) alleviates epiphora by fistulizing the lacrimal sac into the nasal cavity, effectively bypassing nasolacrimal duct obstruction (NLDO). Conventionally performed via an external approach, it is increasi…
View article: Net Benefit of Early Anticoagulation for Stroke With Atrial Fibrillation
Net Benefit of Early Anticoagulation for Stroke With Atrial Fibrillation Open
Importance The net clinical effect of early vs later direct oral anticoagulant (DOAC) initiation after atrial fibrillation–associated ischemic stroke is unclear. Objective To investigate whether early DOAC treatment is associated with a ne…
View article: Statin therapy in ischemic stroke patients with atrial fibrillation: Efficacy and safety outcomes
Statin therapy in ischemic stroke patients with atrial fibrillation: Efficacy and safety outcomes Open
Introduction: The efficacy and safety of statins for secondary prevention in patients who have experienced a cardioembolic stroke are not well-defined. However, previous observational data reported hyperlipidemia as a risk factor for both …
View article: Child Life Services and its impact on Pediatric Oncology Patients and their Parents
Child Life Services and its impact on Pediatric Oncology Patients and their Parents Open
View article: Mortality Risk in Patients With Cardiac Complications Following Ischemic Stroke: A Report From the Virtual International Stroke Trials Archive
Mortality Risk in Patients With Cardiac Complications Following Ischemic Stroke: A Report From the Virtual International Stroke Trials Archive Open
Background Cardiac complications may occur in patients following ischemic stroke (stroke‐heart syndrome [SHS]). We investigated the mortality risk in patients with SHS and across the SHS manifestations. Methods and Results Data were sought…
View article: Machine learning for stroke in heart failure with reduced ejection fraction but without atrial fibrillation: A post‐hoc analysis of the <scp>WARCEF</scp> trial
Machine learning for stroke in heart failure with reduced ejection fraction but without atrial fibrillation: A post‐hoc analysis of the <span>WARCEF</span> trial Open
Background The prediction of ischaemic stroke in patients with heart failure with reduced ejection fraction (HFrEF) but without atrial fibrillation (AF) remains challenging. Our aim was to evaluate the performance of machine learning (ML) …
View article: Incident dementia in ischaemic stroke patients with early cardiac complications: A propensity-score matched cohort study
Incident dementia in ischaemic stroke patients with early cardiac complications: A propensity-score matched cohort study Open
Introduction: The risk of dementia in patients with stroke-heart syndrome (SHS) remains unexplored. Patients and methods: Retrospective analysis using the TriNetX network, including patients with ischaemic stroke from 2010 to 2020. These p…
View article: Initial blood pressure and adverse cardiac events following acute ischaemic stroke: An individual patient data pooled analysis from the VISTA database
Initial blood pressure and adverse cardiac events following acute ischaemic stroke: An individual patient data pooled analysis from the VISTA database Open
Background: Adverse cardiac events following ischaemic stroke (stroke-heart syndrome, SHS) pose a clinical challenge. We investigated the association between initial blood pressure at stroke presentation and the risk of SHS. Methods: We ut…
View article: Stroke-heart syndrome and early mortality in patients with acute ischaemic stroke using hierarchical cluster analysis: An individual patient data pooled analysis from the VISTA database
Stroke-heart syndrome and early mortality in patients with acute ischaemic stroke using hierarchical cluster analysis: An individual patient data pooled analysis from the VISTA database Open
Background: The patient clinical phenotypes at particularly high risk for early cardiac complications after a recent acute ischaemic stroke (AIS), that is, stroke-heart syndrome (SHS), remain poorly defined. We utilised hierarchical cluste…
View article: Incidence and Outcomes of Patients With Early Cardiac Complications After Intracerebral Hemorrhage: A Report From VISTA
Incidence and Outcomes of Patients With Early Cardiac Complications After Intracerebral Hemorrhage: A Report From VISTA Open
BACKGROUND: The incidence and outcomes of early cardiac complications in patients with intracerebral hemorrhage (ICH) are poorly understood. These cardiac complications may be part of the so-called stroke-heart syndrome in patients with IC…
View article: Residual Risks of Thrombotic Complications in Anticoagulated Patients with Atrial Fibrillation: A Cluster Analysis Approach from the GLORIA-AF Registry
Residual Risks of Thrombotic Complications in Anticoagulated Patients with Atrial Fibrillation: A Cluster Analysis Approach from the GLORIA-AF Registry Open
View article: Early statin use is associated with improved survival and cardiovascular outcomes in patients with atrial fibrillation and recent ischaemic stroke: A propensity-matched analysis of a global federated health database
Early statin use is associated with improved survival and cardiovascular outcomes in patients with atrial fibrillation and recent ischaemic stroke: A propensity-matched analysis of a global federated health database Open
Introduction: Statins reduce recurrent stroke and cardiovascular events in patients with non-cardioembolic stroke. The benefits of statins in patients with AF and recent IS remain unclear. We aimed to investigate the benefits of statins in…
View article: Stroke-heart syndrome: Incidence and clinical outcomes of cardiac complications following intracerebral haemorrhage
Stroke-heart syndrome: Incidence and clinical outcomes of cardiac complications following intracerebral haemorrhage Open
Introduction: Newly diagnosed cardiovascular complications following an ischaemic stroke, termed stroke-heart syndrome, are common and associated with worse outcomes. Little is known regarding stroke-heart syndrome in relation to intracere…
View article: Natriuretic Peptides to Classify Risk of Atrial Fibrillation Detection After Stroke
Natriuretic Peptides to Classify Risk of Atrial Fibrillation Detection After Stroke Open
NCT02274727; clinicaltrials.gov/study/NCT02274727.
View article: Global access to technologies to support safe and effective inguinal hernia surgery: prospective, international cohort study
Global access to technologies to support safe and effective inguinal hernia surgery: prospective, international cohort study Open
Technological advancement is important to improve healthcare quality and safety, especially in surgery1. For patients with an inguinal hernia, mesh and minimally invasive surgery are the two main technologies that have improved healthcare …
View article: Early vs Late Anticoagulation in Minor, Moderate, and Major Ischemic Stroke With Atrial Fibrillation
Early vs Late Anticoagulation in Minor, Moderate, and Major Ischemic Stroke With Atrial Fibrillation Open
Importance Whether infarct size modifies the treatment effect of early vs late direct oral anticoagulant (DOAC) initiation in people with ischemic stroke and atrial fibrillation is unknown. Objective To assess whether infarct size modifies…
View article: Reperfusion therapies in patients with acute ischaemic stroke and atrial fibrillation: data on safety and effectiveness from a multi-centre cohort study
Reperfusion therapies in patients with acute ischaemic stroke and atrial fibrillation: data on safety and effectiveness from a multi-centre cohort study Open
View article: Early statin use is associated with improved survival and cardiovascular outcomes in patients with atrial fibrillation and recent ischaemic stroke
Early statin use is associated with improved survival and cardiovascular outcomes in patients with atrial fibrillation and recent ischaemic stroke Open
Background Statins reduce recurrent stroke and cardiovascular events in patients with non-cardioembolic stroke. We aimed to investigate the benefits of statins in patients with atrial fibrillation (AF) and recent ischaemic stroke (IS), whi…
View article: European Stroke Organisation (ESO) Guidelines on the diagnosis and management of patent foramen ovale (PFO) after stroke
European Stroke Organisation (ESO) Guidelines on the diagnosis and management of patent foramen ovale (PFO) after stroke Open
Patent foramen ovale (PFO) is frequently identified in young patients with cryptogenic ischaemic stroke. Potential stroke mechanisms include paradoxical embolism from a venous clot which traverses the PFO, in situ clot formation within the…
View article: Statin Therapy in Ischemic Stroke Patients with Atrial Fibrillation: Efficacy and Safety Outcomes
Statin Therapy in Ischemic Stroke Patients with Atrial Fibrillation: Efficacy and Safety Outcomes Open
Background The efficacy and safety of statins for secondary prevention in patients who have experienced a cardioembolic stroke are not well-defined. However, previous observational data reported hyperlipidemia as a risk factor for both isc…
View article: Albumin Levels and Risk of Early Cardiovascular Complications After Ischemic Stroke: A Propensity-Matched Analysis of a Global Federated Health Network
Albumin Levels and Risk of Early Cardiovascular Complications After Ischemic Stroke: A Propensity-Matched Analysis of a Global Federated Health Network Open
BACKGROUND: No studies have investigated the association between albumin levels and the risk of early cardiovascular complications in patients with ischemic stroke. METHODS: Retrospective analysis with a federated research network (TriNetX…
View article: Challenging anticoagulation decisions in atrial fibrillation: a narrative review
Challenging anticoagulation decisions in atrial fibrillation: a narrative review Open
Atrial fibrillation (AF) is common and warrants consideration of oral anticoagulant (OAC) medication. Usually, the decision is straightforward, following the pathway outlined in the European Society of Cardiology’s guideline; however, cert…
View article: The Impact of Atherosclerotic Burden on Vascular Outcomes in Patients with Stroke and Atrial Fibrillation: The ATHENA study
The Impact of Atherosclerotic Burden on Vascular Outcomes in Patients with Stroke and Atrial Fibrillation: The ATHENA study Open
Introduction: Patients with ischemic stroke (IS) and atrial fibrillation (AF) face a higher risk of recurrent vascular events. This study evaluates the impact of atherosclerotic vascular disease burden across different vascular territories…
View article: Social determinants of health and clinical outcomes among patients with atrial fibrillation: evidence from a global federated health research network
Social determinants of health and clinical outcomes among patients with atrial fibrillation: evidence from a global federated health research network Open
Summary Background Few studies have investigated the role of social determinants of health (SDoH) in patients with atrial fibrillation (AF). Aim To investigate the relationship between SDoH and adverse events in a large multinational AF co…
View article: Atrial fibrillation and stroke: State-of-the-art and future directions
Atrial fibrillation and stroke: State-of-the-art and future directions Open
View article: Management of ischaemic stroke survivors in primary care setting: the road to holistic care
Management of ischaemic stroke survivors in primary care setting: the road to holistic care Open