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View article: Impact of Soil Ameliorants on Soil Chemical Characteristics, Sugar Beet Water Productivity, and Yield Components in Sandy Soils Under Deficit Irrigation
Impact of Soil Ameliorants on Soil Chemical Characteristics, Sugar Beet Water Productivity, and Yield Components in Sandy Soils Under Deficit Irrigation Open
In many sustainable agricultural systems, combining soil ameliorants with deficit irrigation is a viable strategy. However, little is known about how this approach affects soil quality, crop water productivity (CWP), and sugar beet (Beta v…
View article: Geraniol Abrogates Aluminum-elicited Testicular Toxicity and Endocrine-sperm Deficits by Curtailing Oxidative Inflammation and Caspase-dependent Apoptosis in Male Rats
Geraniol Abrogates Aluminum-elicited Testicular Toxicity and Endocrine-sperm Deficits by Curtailing Oxidative Inflammation and Caspase-dependent Apoptosis in Male Rats Open
Background: Aluminum (Al) is a ubiquitous environmental toxicant associated with adverse effect on the testis. Thus, we investigated the protective effect of GER against Al-induced testicular injury and endocrine-sperm deficits in male rat…
View article: Geraniol prevents CCl4-induced hepatotoxicity via suppression of hepatic oxidative stress, pro-inflammation and apoptosis in rats
Geraniol prevents CCl4-induced hepatotoxicity via suppression of hepatic oxidative stress, pro-inflammation and apoptosis in rats Open
Carbon tetrachloride (CCl4) is a classic chemical hepatotoxicant that triggers liver damage through hepatic exacerbation of oxidative stress. Geraniol (GRL) is a natural bioactive acyclic monoterpene with several pharmacological…
View article: Lipoic acid abates testis lead accumulation, sperm-endocrine deficits, testicular oxidative inflammation and apoptosis and modulates gene expression of Bax and Bcl-2 in rats
Lipoic acid abates testis lead accumulation, sperm-endocrine deficits, testicular oxidative inflammation and apoptosis and modulates gene expression of Bax and Bcl-2 in rats Open
The current study explored whether ALA could prevent testis Pb accumulation and Pb-induced oxidative testicular toxicity in rats. Adult male rats were randomly divided and administered ALA (25 mg/kg/day) and/or Pb (Pb acetate, 20 mg/kg/day…
View article: Hepatoprotective Mechanism of Apigenin via Suppression of Oxidative Inflammatory Signaling and Apoptosis against Hepatotoxicity Induced by CCl4 in Rats
Hepatoprotective Mechanism of Apigenin via Suppression of Oxidative Inflammatory Signaling and Apoptosis against Hepatotoxicity Induced by CCl4 in Rats Open
Background: Carbon tetrachloride (CCl4) is a critical hepatotoxicant causing liver injury and fibrosis via hepatic production of reactive oxygen species (ROS). Apigenin (APG) is a natural bioactive compound and flavonoid antioxidant. We, t…
View article: Properties of Nano-Amendments and Their Effect on Some Soil Properties and Root-Knot Nematode and Yield Attributes of Tomato Plant
Properties of Nano-Amendments and Their Effect on Some Soil Properties and Root-Knot Nematode and Yield Attributes of Tomato Plant Open
The use of green nano-amendments is a promising approach for improving soil health and providing sustainable options to reduce root-knot nematodes (RKN) and thus increase yields. Therefore, the purpose of this research was to identify the …
View article: Resveratrol Mitigates Diabetic Testicular Dysfunction, Endocrine Deficits, and Insulin Resistance via Suppression of Sperm‐Endocrine Aberrations and Oxidative Inflammation in Rats
Resveratrol Mitigates Diabetic Testicular Dysfunction, Endocrine Deficits, and Insulin Resistance via Suppression of Sperm‐Endocrine Aberrations and Oxidative Inflammation in Rats Open
Diabetes mellitus (DM) provokes reproductive impairments through endocrine disturbance, sperm deficits, and testicular oxidative inflammation. The study investigated the reproductive protective effects of resveratrol (RSV) against testicul…
View article: Properties of Recycled Nanomaterials and Their Effect on Biological Activity and Yield of Canola in Degraded Soils
Properties of Recycled Nanomaterials and Their Effect on Biological Activity and Yield of Canola in Degraded Soils Open
Recycling waste, such as rice straw and water treatment residuals, is important to reduce harmful effects on the environment and to improve canola yield and soil quality in degraded soils. Nanotechnology for the production of nanomaterials…
View article: Betamethasone Toxicity Induced by Topical Maternal Exposure Prior to Fertilization in Heart of Newborn Rabbits
Betamethasone Toxicity Induced by Topical Maternal Exposure Prior to Fertilization in Heart of Newborn Rabbits Open
Background: Betamethasone treatment is widely used and recommended worldwide. Although, there are no enough studies to look for the risk or potential alterations due to accumulation of this drug before fertilization. In addition, previous …
View article: Capric Acid Behaves Agonistic Effect on Calcitriol to Control Inflammatory Mediators in Colon Cancer Cells
Capric Acid Behaves Agonistic Effect on Calcitriol to Control Inflammatory Mediators in Colon Cancer Cells Open
Inflammation prompts cancer development and promotes all stages of tumorigenesis. Calcitriol is a nutraceutical essential regulator for host health benefits. However, the influence of calcitriol on inflammatory mediators involved in cancer…
View article: Acacetin Inhibits Cell Proliferation and Induces Apoptosis in Human Hepatocellular Carcinoma Cell Lines
Acacetin Inhibits Cell Proliferation and Induces Apoptosis in Human Hepatocellular Carcinoma Cell Lines Open
Human hepatocellular carcinoma (HCC) is the fifth most common cancer and the third leading cause of death across the world. Recent evidence suggests that STAT3 regulates proliferative, survival, metastasis, and angiogenesis genes in HCC. N…
View article: Apigenin Ameliorates Lead Acetate Induced Hyperlipidemia and Hypogonadism in Male Rats
Apigenin Ameliorates Lead Acetate Induced Hyperlipidemia and Hypogonadism in Male Rats Open
Background: Lead (Pb) is an environmental pollutant and has detrimental effects on human health. Apigenin (APG) is a flavonoid that have antioxidant, anti-inflammatory and antiallergic and cardioprotective so is used as treatment of many d…
View article: Protective Potential of Apigenin against Lead Acetate Induced Alterations in Cerebellum of Rats
Protective Potential of Apigenin against Lead Acetate Induced Alterations in Cerebellum of Rats Open
Background: Lead (Pb) is a heavy metal that represents an environmental toxicant causing serious health problem. Apigenin (APG) is a plant derived flavonoid with several therapeutic activities. So, the aim of the present study was to deter…
View article: Antidiabetic Wound Dressing Materials Based on Cellulosic Fabrics Loaded with Zinc Oxide Nanoparticles Synthesized by Solid-State Method
Antidiabetic Wound Dressing Materials Based on Cellulosic Fabrics Loaded with Zinc Oxide Nanoparticles Synthesized by Solid-State Method Open
The current study aims for the use of the solid-state technique as an efficient way for the preparation of zinc oxide nanoparticles (ZnONPs) as an antimicrobial agent with high concentration using sodium alginate as stabilizing agent. ZnON…
View article: Hepatorenal Toxicity Induced by Maternal Exposure to Topical Betamethasone Prior to Fertilization in Newborn Rabbits
Hepatorenal Toxicity Induced by Maternal Exposure to Topical Betamethasone Prior to Fertilization in Newborn Rabbits Open
Background: Synthetic glucocorticoids, such as Betamethasone, are used for treatment of skin disease including Psoriasis. No enough evidences are present about the side effect of maternal exposure to betamethasone, before fertilization, on…
View article: Cerebellar Toxicity Induced by Maternal Exposure to Topical Betamethasone Prior to Fertilization in Newborn Rabbits
Cerebellar Toxicity Induced by Maternal Exposure to Topical Betamethasone Prior to Fertilization in Newborn Rabbits Open
Background: Betamethasone is a synthetic glucocorticoid used for treatment of Psoriasis. Until now, the side effect of maternal exposure to topical betamethasone, prior to fertilization, on newborn is not clear. So, the aim of the present …
View article: Brassinin Enhances Apoptosis in Hepatic Carcinoma by Inducing Reactive Oxygen Species Production and Suppressing the JAK2/STAT3 Pathway
Brassinin Enhances Apoptosis in Hepatic Carcinoma by Inducing Reactive Oxygen Species Production and Suppressing the JAK2/STAT3 Pathway Open
Plants from the family Brassicaceae produce brassinin (BSN), which is an essential indole phytoalexin. BSN can kill certain types of cancer cells. Using hepatocarcinoma (HCC) cells, we examined the molecular mechanisms of BSN. We found tha…
View article: Apigenin Ameliorates Lead Acetate induced Hyperlipidemia, Hypothyroidism and Hypogonadism in Male Rats
Apigenin Ameliorates Lead Acetate induced Hyperlipidemia, Hypothyroidism and Hypogonadism in Male Rats Open
Lead (Pb) is an environmental pollutant and has detrimental effects on human health. Apigenin (APG) is a flavonoid that have antioxidant, anti-inflammatory, antiallergic, and cardioprotective effects and is presented as treatment of some d…
View article: Naringin alleviates methotrexate-induced liver injury in male albino rats and enhances its antitumor efficacy in HepG2 cells
Naringin alleviates methotrexate-induced liver injury in male albino rats and enhances its antitumor efficacy in HepG2 cells Open
Methotrexate (MTX) is an efficient chemotherapeutic and immunosuppressant drug, but the hepatotoxicity of MTX limits its clinical use. Naringin (Nar) is a flavonoid derived from Citrus paradise, and has been shown to possess several pharma…
View article: Rutin ameliorates carbon tetrachloride (CCl<sub>4</sub>)-induced hepatorenal toxicity and hypogonadism in male rats
Rutin ameliorates carbon tetrachloride (CCl<sub>4</sub>)-induced hepatorenal toxicity and hypogonadism in male rats Open
Rutin, a food derived-polyphenolic bioflavonoid, has been acknowledged for several health benefits. This study aims to explore the ameliorative effects of rutin against carbon tetrachloride (CCl 4 ) toxicity in male rats. Adult male rats w…
View article: Protective Potential of Quercetin on Cd-Induced Hepatorenal Damage
Protective Potential of Quercetin on Cd-Induced Hepatorenal Damage Open
Industrial and environmental pollution are sources of cadmium (Cd) exposure that cause serious health hazards.In this work we investigated the protective effect of quercetin on Cd-induced hepatorenal damage in rats.Cd toxicity was confirme…
View article: Gasoline induced pulmo- oxidative damage in mice model
Gasoline induced pulmo- oxidative damage in mice model Open
The present work aims to evaluatethe cytotoxic effects on lung cells exerted by gasoline. 60 male albino mice were used in the present experiment, divided equally into 3 groups: first group (control) was left access to fresh air, second gr…
View article: Hepatotoxicity of Gasoline as an Environmental Pollutant on Albino Mice
Hepatotoxicity of Gasoline as an Environmental Pollutant on Albino Mice Open
This study focuses on finding if the hazards produced by gasoline 90 (vehicle fuel in Egypt) are less than those produced by gasoline 80 in healthy Swiss albino mice.Sixty mice were equally divided into 3 groups: group one (control), group…