Amir Askari
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View article: The sodium pump and digitalis drugs: Dogmas and fallacies
The sodium pump and digitalis drugs: Dogmas and fallacies Open
The sodium pump (Na/K‐ATPase) is a plasma membrane enzyme that transports Na + and K + against their physiological gradients in most eukaryotic cells. Besides pumping ions, the enzyme may also interact with neighboring proteins to activate…
View article: Comparison of Digitalis Sensitivities of Na<sup>+</sup>/K<sup>+</sup>-ATPases from Human and Pig Kidneys
Comparison of Digitalis Sensitivities of Na<sup>+</sup>/K<sup>+</sup>-ATPases from Human and Pig Kidneys Open
Digitalis drugs are selective inhibitors of the plasma membrane Na+/K+-ATPase. There are many studies on molecular mechanisms of digitalis interaction with purified pig kidney enzyme, with the tacit assumption that it is a good model of hu…