B. Bemiss
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View article: REN: Anatomically-Informed Mixture-of-Experts for Interstitial Lung Disease Diagnosis
REN: Anatomically-Informed Mixture-of-Experts for Interstitial Lung Disease Diagnosis Open
Mixture-of-Experts (MoE) architectures have significantly contributed to scalable machine learning by enabling specialized subnetworks to tackle complex tasks efficiently. However, traditional MoE systems lack domain-specific constraints e…
View article: Profibrotic monocyte-derived alveolar macrophages as a biomarker and therapeutic target in systemic sclerosis-associated interstitial lung disease
Profibrotic monocyte-derived alveolar macrophages as a biomarker and therapeutic target in systemic sclerosis-associated interstitial lung disease Open
Interstitial lung disease (ILD) is present in over 60% of patients with systemic sclerosis (SSc) and is the leading cause of SSc-related deaths. Profibrotic monocyte-derived alveolar macrophages (MoAM) play a causal role in the pathogenesi…
View article: Post-Operative Atrial Arrhythmias after Lung Transplantation: A Single Center Analysis of Risk Factors, Management, and Outcomes
Post-Operative Atrial Arrhythmias after Lung Transplantation: A Single Center Analysis of Risk Factors, Management, and Outcomes Open
Background Following lung transplant, many patients develop post-operative atrial fibrillation (AF) or atrial flutter (AFL)–collectively defined as post-operative atrial arrhythmia (POAA). While early (in-hospital) POAA is linked to increa…
View article: Machine Learning Analysis of Electronic Health Records Identifies Interstitial Lung Disease and Predicts Mortality in Patients with Systemic Sclerosis
Machine Learning Analysis of Electronic Health Records Identifies Interstitial Lung Disease and Predicts Mortality in Patients with Systemic Sclerosis Open
Background Interstitial lung disease (ILD) is the leading cause of death in patients with systemic sclerosis (SSc), affecting more than 40% of this population. Despite the availability of effective treatments to stabilize or improve lung f…
View article: <i>In silico</i>perturbations provide multivariate interpretability in predicting post-lung transplant outcomes
<i>In silico</i>perturbations provide multivariate interpretability in predicting post-lung transplant outcomes Open
Lung transplantation is a life-saving therapy for end-stage lung disease but has the poorest survival among solid organ transplants. We analyzed standardized electronic health record (EHR) data from the United Network for Organ Sharing (UN…
View article: 2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Treatment of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases
2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Treatment of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases Open
Objective We provide evidence‐based recommendations regarding the treatment of interstitial lung disease (ILD) in adults with systemic autoimmune rheumatic diseases (SARDs). Methods We developed clinically relevant population, intervention…
View article: 2023 American College of Rheumatology (<scp>ACR</scp>)/American College of Chest Physicians (<scp>CHEST</scp>) Guideline for the Screening and Monitoring of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases
2023 American College of Rheumatology (<span>ACR</span>)/American College of Chest Physicians (<span>CHEST</span>) Guideline for the Screening and Monitoring of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases Open
Objective We provide evidence‐based recommendations regarding screening for interstitial lung disease (ILD) and the monitoring for ILD progression in people with systemic autoimmune rheumatic diseases (SARDs), specifically rheumatoid arthr…
View article: Multicenter analysis of immunosuppressive medications on the risk of malignancy following adult solid organ transplantation
Multicenter analysis of immunosuppressive medications on the risk of malignancy following adult solid organ transplantation Open
Objective This study aimed to assess the risk of maintenance immunosuppression on the post-transplant risk of malignancy across all solid organ transplant types. Methods This is a retrospective cohort study from a multicenter hospital syst…
View article: Multicenter analysis of immunosuppressive medications on the subsequent risk of malignancy in solid organ transplant recipients
Multicenter analysis of immunosuppressive medications on the subsequent risk of malignancy in solid organ transplant recipients Open
Solid organ transplant is a curative treatment for end organ disease. However, the immunosuppressive therapy required to prevent graft rejection increases the likelihood of developing a subsequent malignancy. This retrospective cohort stud…
View article: Effect of Antimicrobial Therapy on Respiratory Hospitalization or Death in Adults With Idiopathic Pulmonary Fibrosis
Effect of Antimicrobial Therapy on Respiratory Hospitalization or Death in Adults With Idiopathic Pulmonary Fibrosis Open
ClinicalTrials.gov Identifier: NCT02759120.