Michael B. Cook
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View article: Supplementary Figure 1 from Circulating Inflammation Biomarkers and the Risk of Esophageal Adenocarcinoma: A Nested Case–Control Study in the Department of Defense Serum Repository
Supplementary Figure 1 from Circulating Inflammation Biomarkers and the Risk of Esophageal Adenocarcinoma: A Nested Case–Control Study in the Department of Defense Serum Repository Open
Supplementary Figure 1. Associations of esophageal adenocarcinoma risk per quantile increase in circulating novel biomarkers in the Department of Defense Serum Repository. Odd ratios (ORs) adjusted for matching variables, marital status an…
View article: Supplementary Table 2 from Circulating Inflammation Biomarkers and the Risk of Esophageal Adenocarcinoma: A Nested Case–Control Study in the Department of Defense Serum Repository
Supplementary Table 2 from Circulating Inflammation Biomarkers and the Risk of Esophageal Adenocarcinoma: A Nested Case–Control Study in the Department of Defense Serum Repository Open
Supplementary Table 2. Associations between replicated biomarkers and esophageal adenocarcinoma risk in the Department of Defense Serum Repository, restricting to matched pairs with cases diagnosed ≥5 and ≥10 years after blood draw.
View article: Supplementary Figure 2 from Circulating Inflammation Biomarkers and the Risk of Esophageal Adenocarcinoma: A Nested Case–Control Study in the Department of Defense Serum Repository
Supplementary Figure 2 from Circulating Inflammation Biomarkers and the Risk of Esophageal Adenocarcinoma: A Nested Case–Control Study in the Department of Defense Serum Repository Open
Supplementary Figure 2. Associations of esophageal adenocarcinoma per quantile increase in circulating novel biomarkers in the Department of Defense Serum Repository. Odd Ratios (ORs) adjusted for matching variables, education, marital sta…
View article: Supplementary Table 1 from Circulating Inflammation Biomarkers and the Risk of Esophageal Adenocarcinoma: A Nested Case–Control Study in the Department of Defense Serum Repository
Supplementary Table 1 from Circulating Inflammation Biomarkers and the Risk of Esophageal Adenocarcinoma: A Nested Case–Control Study in the Department of Defense Serum Repository Open
Supplementary Table 1. Performance characteristics of measurement of 276 inflammation (blue), oncology (red) and cardiovascular (black) biomarkers in the Department of Defense Serum Repository.
View article: Data from Circulating Inflammation Biomarkers and the Risk of Esophageal Adenocarcinoma: A Nested Case–Control Study in the Department of Defense Serum Repository
Data from Circulating Inflammation Biomarkers and the Risk of Esophageal Adenocarcinoma: A Nested Case–Control Study in the Department of Defense Serum Repository Open
Background:We previously identified associations of esophageal adenocarcinoma risk with four inflammation-related candidate biomarkers: TNF receptor 2 (TNFR2), IL17A, VEGFR3, and resistin.Methods:We aimed to replicate these candidates and …
View article: Supplementary Table 3 from Circulating Inflammation Biomarkers and the Risk of Esophageal Adenocarcinoma: A Nested Case–Control Study in the Department of Defense Serum Repository
Supplementary Table 3 from Circulating Inflammation Biomarkers and the Risk of Esophageal Adenocarcinoma: A Nested Case–Control Study in the Department of Defense Serum Repository Open
Supplementary Table 3. Spearman's correlation coefficents among candidate biomarkers in Department of Defense Serum Repository.
View article: Circulating Inflammation Biomarkers and the Risk of Esophageal Adenocarcinoma: A Nested Case–Control Study in the Department of Defense Serum Repository
Circulating Inflammation Biomarkers and the Risk of Esophageal Adenocarcinoma: A Nested Case–Control Study in the Department of Defense Serum Repository Open
Background: We previously identified associations of esophageal adenocarcinoma risk with four inflammation-related candidate biomarkers: TNF receptor 2 (TNFR2), IL17A, VEGFR3, and resistin. Methods: We aimed to replicate these candidates a…
View article: The Importance of Representative Likeness: Why we Should Represent Interactive Digital Narrative with Interaction
The Importance of Representative Likeness: Why we Should Represent Interactive Digital Narrative with Interaction Open
Scholarly work on Interactive Digital Narrative (IDN) has long been communicated using the non-interactive format of the academic paper. Yet, when we only tell or show, we do not interact, which means that we lose the most important aspect…
View article: Similar Risk of Kidney Failure among Patients with Blinding Diseases Who Receive Ranibizumab, Aflibercept, and Bevacizumab
Similar Risk of Kidney Failure among Patients with Blinding Diseases Who Receive Ranibizumab, Aflibercept, and Bevacizumab Open
Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
View article: Comparative Effectiveness of Second-line Antihyperglycemic Agents for Cardiovascular Outcomes: A Large-scale, Multinational, Federated Analysis of the LEGEND-T2DM Study
Comparative Effectiveness of Second-line Antihyperglycemic Agents for Cardiovascular Outcomes: A Large-scale, Multinational, Federated Analysis of the LEGEND-T2DM Study Open
Background SGLT2 inhibitors (SGLT2is) and GLP-1 receptor agonists (GLP1-RAs) reduce major adverse cardiovascular events (MACE) in patients with type 2 diabetes mellitus (T2DM). However, their effectiveness relative to each other and other …
View article: P1156 Characteristics and outcomes of over a million Inflammatory Bowel Disease patients in seven countries: a multinational cohort study
P1156 Characteristics and outcomes of over a million Inflammatory Bowel Disease patients in seven countries: a multinational cohort study Open
Background Population-based studies are crucial for gaining insights into epidemiology, risk factors, and outcomes of IBD. However, studies that characterize patient cohorts typically analyze a single resource, apply diverse eligibility cr…
View article: Multinational patterns of second line antihyperglycaemic drug initiation across cardiovascular risk groups: federated pharmacoepidemiological evaluation in LEGEND-T2DM
Multinational patterns of second line antihyperglycaemic drug initiation across cardiovascular risk groups: federated pharmacoepidemiological evaluation in LEGEND-T2DM Open
Objective To assess the uptake of second line antihyperglycaemic drugs among patients with type 2 diabetes mellitus who are receiving metformin. Design Federated pharmacoepidemiological evaluation in LEGEND-T2DM. Setting 10 US and seven no…
View article: Overall and abdominal obesity and prostate cancer risk in a West African population: An analysis of the Ghana Prostate Study
Overall and abdominal obesity and prostate cancer risk in a West African population: An analysis of the Ghana Prostate Study Open
Obesity has been associated with an increased risk of advanced prostate cancer. However, most studies have been conducted among North American and European populations. Prostate cancer mortality appears elevated in West Africa, yet risk fa…
View article: Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry
Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry Open
Genome-wide polygenic risk scores (GW-PRS) have been reported to have better predictive ability than PRS based on genome-wide significance thresholds across numerous traits. We compared the predictive ability of several GW-PRS approaches t…
View article: 'That Darned Sandstorm': A Study of Procedural Generation through Archaeological Storytelling
'That Darned Sandstorm': A Study of Procedural Generation through Archaeological Storytelling Open
Procedural content generation has been applied to many domains, especially level design, but the narrative affordances of generated game environments are comparatively understudied. In this paper we present our first attempt to study these…
View article: Supplementary Table 3 from Do Aspirin and Other NSAIDs Confer a Survival Benefit in Men Diagnosed with Prostate Cancer? A Pooled Analysis of NIH-AARP and PLCO Cohorts
Supplementary Table 3 from Do Aspirin and Other NSAIDs Confer a Survival Benefit in Men Diagnosed with Prostate Cancer? A Pooled Analysis of NIH-AARP and PLCO Cohorts Open
Four-level frequency of pre-diagnostic NSAID use in relation to mortality.
View article: Supplementary Table 2 from Do Aspirin and Other NSAIDs Confer a Survival Benefit in Men Diagnosed with Prostate Cancer? A Pooled Analysis of NIH-AARP and PLCO Cohorts
Supplementary Table 2 from Do Aspirin and Other NSAIDs Confer a Survival Benefit in Men Diagnosed with Prostate Cancer? A Pooled Analysis of NIH-AARP and PLCO Cohorts Open
Characteristics of prostate cancer cases by status of NSAID use in the past year in the post-diagnostic NIH-AARP and PLCO cohorts.