Bruce Bartholow Duncan
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Associations between distinct sedentary behaviors with dementia risk and brain structure: findings of the ARIC Study Open
Background Longitudinal studies exploring the associations of sedentary behavior (SB) in different contexts with brain structure remain limited. We aimed to examine the association of SB at leisure and work with the risk of dementia and br…
Does “every move count” for cognitive decline? Findings of the ELSA‐Brasil study Open
Background Studies investigating the association of physical activity (PA) with cognitive decline usually do not characterize the parameters of PA, especially the domains in life in which PA occurs such as at leisure and commuting. We eval…
Early menopause and menacme was associated with cognitive decline in ELSA‐Brasil cohort study Open
Background Early menopause (EM) and total time of menstruation (menacme) has recently been studied as potential risk factors for dementia. However, the evidence in the literature shows conflicting results. We aim is to evaluate EM and mena…
Association of Metabolic dysfunction‐associated steatotic liver disease, MASLD, with Cognitive Function in a Brazilian Cohort Open
Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) has recently been studied as a potential risk factor for cognitive decline (CD). However, the evidence in the literature shows conflicting results. We aim to evalu…
Distinct sedentary behaviors and cognitive decline: Findings of the ELSA‐Brasil study Open
Background Sedentary behavior (SB) has been associated with adverse cognitive outcomes. Mentally active sedentary behavior and PA may mitigate the negative impact of SB on brain health. We aimed to investigate the association between conte…
View article: Prediction of Atrial Fibrillation From the ECG in the Community Using Deep Learning: A Multinational Study
Prediction of Atrial Fibrillation From the ECG in the Community Using Deep Learning: A Multinational Study Open
BACKGROUND: We aimed to refine and validate a deep neural network model from the ECG to predict atrial fibrillation (AF) risk, using samples from diverse backgrounds: the Framingham Heart Study (FHS), UK Biobank, and Estudo Longitudinal da…
View article: Population attributable fractions of modifiable dementia risk factors for cognitive impairment—the ELSA-Brasil cohort study
Population attributable fractions of modifiable dementia risk factors for cognitive impairment—the ELSA-Brasil cohort study Open
RMC received Alzheimer's Association grant (AARGD-21-846545).
View article: World health Organization’s guidance for tracking non-communicable diseases towards sustainable development goals 3.4: an initiative for facility-based monitoring
World health Organization’s guidance for tracking non-communicable diseases towards sustainable development goals 3.4: an initiative for facility-based monitoring Open
This study was funded internally by WHO.
View article: Reply to van Bruggen, F.H.; Luijendijk, H.J. Comment on “Chwal et al. On-Target Low-Density Lipoprotein Cholesterol in Adults with Diabetes Not at High Cardiovascular Disease Risk Predicts Greater Mortality, Independent of Early Deaths or Frailty. J. Clin. Med. 2024, 13, 7667”
Reply to van Bruggen, F.H.; Luijendijk, H.J. Comment on “Chwal et al. On-Target Low-Density Lipoprotein Cholesterol in Adults with Diabetes Not at High Cardiovascular Disease Risk Predicts Greater Mortality, Independent of Early Deaths or Frailty. J. Clin. Med. 2024, 13, 7667” Open
We thank Drs [...]
View article: The effect of redistributions of garbage codes on the evolution of mortality from Chronic Diseases in Brazil, 2010 to 2019
The effect of redistributions of garbage codes on the evolution of mortality from Chronic Diseases in Brazil, 2010 to 2019 Open
This study aimed to estimate premature mortality (30-69 years) for four priority NCD groups in Brazil from 2010 to 2019, comparing crude data from the Mortality Information System (SIM), SIM data adjusted by GC redistribution and underrepo…
View article: Prevalence and Mortality of Heart Failure Stages in a Free‐Living Older Adult Population: Data From the Brazilian Longitudinal Study of Adult Health
Prevalence and Mortality of Heart Failure Stages in a Free‐Living Older Adult Population: Data From the Brazilian Longitudinal Study of Adult Health Open
Background Heart failure (HF) has a major impact on public health. HF staging helps capture preclinical disease and its progression to advanced stages. There are scarce data on HF staging from longitudinal studies in Latin America. This st…
View article: Characteristics Associated with Prevalent Atrial Fibrillation and Risk Profile for Incident Atrial Fibrillation an Elderly Population from ELSA-Brasil.
Characteristics Associated with Prevalent Atrial Fibrillation and Risk Profile for Incident Atrial Fibrillation an Elderly Population from ELSA-Brasil. Open
AFF was found in 4.2% of this older Brazilian cohort. AFF was linked to HF history, LBBB, left atrial dilation, and reduced LVEF. Additionally, 12% to 13% of patients in sinus rhythm were at high risk for AFF. Monitoring clinical, electroc…
View article: Difference in the prevalence of hypertension when measured according to the American Heart Association and the European Society of Cardiology hypertension cut-offs in the ELSA-Brasil cohort
Difference in the prevalence of hypertension when measured according to the American Heart Association and the European Society of Cardiology hypertension cut-offs in the ELSA-Brasil cohort Open
The 2017 US guidelines for the prevention, detection, evaluation, and management of high blood pressure in adults proposed the diagnosis of hypertension at 130/80 mmHg, while the European Society of Cardiology and 2020 Brazilian Guidelines…
View article: On-Target Low-Density Lipoprotein Cholesterol in Adults with Diabetes Not at High Cardiovascular Disease Risk Predicts Greater Mortality, Independent of Early Deaths or Frailty
On-Target Low-Density Lipoprotein Cholesterol in Adults with Diabetes Not at High Cardiovascular Disease Risk Predicts Greater Mortality, Independent of Early Deaths or Frailty Open
Background/Objectives: Lowering low-density lipoprotein cholesterol (LDL-C) to 60 years (HR = 2.12; 95%CI 1.35–3.34) and greatest for deaths due to cancer (HR = 2.55; 95%CI 1.10–5.91). Further analyses for those with LDL-C < 100 mg/dL that…
View article: Associations of Ultra-Processed Food Intake with the Incidence of Cardiometabolic and Mental Health Outcomes Go Beyond Specific Subgroups—The Brazilian Longitudinal Study of Adult Health
Associations of Ultra-Processed Food Intake with the Incidence of Cardiometabolic and Mental Health Outcomes Go Beyond Specific Subgroups—The Brazilian Longitudinal Study of Adult Health Open
Background/Objectives: Avoidance of ultra-processed foods (UPFs) has been recommended to achieve a healthy diet, but whether it applies equally to all UPFs is uncertain. We evaluated individual UPF subgroups in the prediction of cardiometa…
View article: Attributable fractions of risk factors for cognitive impairment in the ELSA‐Brasil cohort
Attributable fractions of risk factors for cognitive impairment in the ELSA‐Brasil cohort Open
Background Attributable fractions (AFs) of the modifiable risk factors of dementia are usually calculated using population‐based samples. Nevertheless, assessing AF within cohorts offers a more nuanced perspective on the impact of these fa…
The McKenzie Method delivered by credentialed therapists for chronic low back pain with directional preference: systematic review with meta-analysis Open
We found low-to-moderate certainty evidence that the McKenzie Method was superior to all other interventions combined for up to 6 months for pain and up to 12 months for disability, with clinically important differences versus exercise in …
View article: Characteristics associated with prevalent atrial fibrillation and risk profile for future atrial fibrillation among those in sinus rhythm in an elderly population in the ELSA Brasil Study
Characteristics associated with prevalent atrial fibrillation and risk profile for future atrial fibrillation among those in sinus rhythm in an elderly population in the ELSA Brasil Study Open
Background Atrial fibrillation (AF) is an arrhythmia that can lead to limiting symptoms and increases the risk of stroke and heart failure (HF). Purpose To evaluate the association of clinical, electrocardiographic, and echocardiographic p…
View article: Telephone lifestyle intervention to prevent diabetes in women with recent gestational diabetes mellitus attending the national health system: the LINDA-Brasil clinical trial
Telephone lifestyle intervention to prevent diabetes in women with recent gestational diabetes mellitus attending the national health system: the LINDA-Brasil clinical trial Open
Objectives To evaluate a postpartum telephone-based lifestyle intervention to prevent diabetes in high-risk women with recent gestational diabetes mellitus (GDM). Design Multicentre parallel randomised clinical trial. Setting Specialised a…