Filippo Cademartiri
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View article: Severity assessment of COVID-19 disease: radiological visual score versus automated quantitative CT parameters using a pneumonia analysis algorithm
Severity assessment of COVID-19 disease: radiological visual score versus automated quantitative CT parameters using a pneumonia analysis algorithm Open
Objective Evaluate the impact of the use of an AI-assisted quantitative tool for assessing stratification of patients with acute lung involvement from coronavirus (COVID-19) compared to a semi-quantitative visual score made by the radiolog…
View article: Heart-Brain axis: is microvascular dysfunction the link between stroke and Takotsubo syndrome?
Heart-Brain axis: is microvascular dysfunction the link between stroke and Takotsubo syndrome? Open
Takotsubo syndrome (TS) is characterized by transient left ventricular dysfunction, often triggered by psychological or physiological stress. Increasing evidence highlights the critical role of the brain-heart axis in TS, with small blood …
View article: Current and future applications of photon-counting computed tomography in cardiovascular medicine
Current and future applications of photon-counting computed tomography in cardiovascular medicine Open
Photon-counting CT (PCCT) represents a transformative advancement in cardiac imaging, addressing key limitations of conventional CT. This review synthesises current evidence to demonstrate how PCCT’s superior spatial resolution, enhanced t…
View article: Defining two dimensional transthoracic echocardiographic aorta dimension reference ranges in healthy subjects: a machine learning based model
Defining two dimensional transthoracic echocardiographic aorta dimension reference ranges in healthy subjects: a machine learning based model Open
Background Proximal aortic dimensions are influenced by a complex interaction of age, sex, and anthropometric factors. Thus defining their full range in healthy subjects remains a challenge, even in the era of artificial intelligence (AI).…
View article: CTA-Derived Plaque Characteristics and Risk of Acute Coronary Syndrome in Patients With Coronary Artery Calcium Score of Zero: Insights From the ICONIC Trial
CTA-Derived Plaque Characteristics and Risk of Acute Coronary Syndrome in Patients With Coronary Artery Calcium Score of Zero: Insights From the ICONIC Trial Open
BACKGROUND. Coronary artery calcium (CAC) scoring is used to stratify acute coronary syndrome (ACS) risk. Nonetheless, patients with a CAC score of zero (CAC0) remain at risk from noncalcified plaque components. OBJECT…
View article: AI-Quantitative CT Coronary Plaque Features Associate With a Higher Relative Risk in Women: CONFIRM2 Registry
AI-Quantitative CT Coronary Plaque Features Associate With a Higher Relative Risk in Women: CONFIRM2 Registry Open
BACKGROUND: Coronary plaque features are imaging biomarkers of cardiovascular risk, but less is known about sex-specific patterns in their prognostic value. This study aimed to define sex differences in the coronary atherosclerotic phenoty…
View article: Atherosclerotic Abdominal Aortic Aneurysms on Computed Tomography Angiography: A Narrative Review on Spectrum of Findings, Structured Reporting, Treatment, Secondary Complications and Differential Diagnosis
Atherosclerotic Abdominal Aortic Aneurysms on Computed Tomography Angiography: A Narrative Review on Spectrum of Findings, Structured Reporting, Treatment, Secondary Complications and Differential Diagnosis Open
Atherosclerotic abdominal aortic aneurysms (AAAs) are a common vascular pathology with significant morbidity and mortality risks. Timely diagnosis, accurate characterization, and standardized reporting are critical for effective management…
View article: Guiding patient-specific cardiac simulations through data-assimilation of soft tissue kinematics from dynamic CT scan
Guiding patient-specific cardiac simulations through data-assimilation of soft tissue kinematics from dynamic CT scan Open
Fluid-structure interaction (FSI) can be key in the generation of accurate digital replica of cardiovascular systems. To personalize these models, however, several patient-specific parameters need to be measured, which can be challenging t…
View article: Voxelwise characterization of noise for a clinical photon-counting CT scanner with a model-based iterative reconstruction algorithm
Voxelwise characterization of noise for a clinical photon-counting CT scanner with a model-based iterative reconstruction algorithm Open
Background Photon-counting detector (PCD) technology has the potential to reduce noise in computed tomography (CT). This study aimed to carry out a voxelwise noise characterization for a clinical PCD-CT scanner with a model-based iterative…
View article: Comparison of biventricular size and function between adult regularly transfused thalassemia intermedia and thalassemia major patients
Comparison of biventricular size and function between adult regularly transfused thalassemia intermedia and thalassemia major patients Open
View article: Magnetic resonance evaluation of tissue iron deposition in adult regularly transfused thalassemia intermedia compared to thalassemia major patients
Magnetic resonance evaluation of tissue iron deposition in adult regularly transfused thalassemia intermedia compared to thalassemia major patients Open
View article: Clinical correlates of left ventricular strain parameters by cardiac magnetic resonance in beta-thalassemia major patients
Clinical correlates of left ventricular strain parameters by cardiac magnetic resonance in beta-thalassemia major patients Open
View article: Early detection of myocardial involvement in thalassemia intermedia patients: multiparametric mapping by cardiovascular magnetic resonance imaging
Early detection of myocardial involvement in thalassemia intermedia patients: multiparametric mapping by cardiovascular magnetic resonance imaging Open
View article: Association between global longitudinal strain by cardiac magnetic resonance and cardiac complications in beta-thalassemia major patients
Association between global longitudinal strain by cardiac magnetic resonance and cardiac complications in beta-thalassemia major patients Open
View article: Health improvements by understanding residual risk in coronary artery disease and new targets for prevention/treatment: rationale and research protocol of the HURRICANE project
Health improvements by understanding residual risk in coronary artery disease and new targets for prevention/treatment: rationale and research protocol of the HURRICANE project Open
Optimal medical treatment in patients with stable coronary artery disease (CAD) reduced morbidity and mortality but left a substantial residual risk (RR) of disease progression and events. According to recent evidence, insulin resistance o…
View article: Biatrial and Biventricular Reference Ranges Based on Cardiac Magnetic Resonance in Sickle Cell Disease Patients Without Heart Damage
Biatrial and Biventricular Reference Ranges Based on Cardiac Magnetic Resonance in Sickle Cell Disease Patients Without Heart Damage Open
Background/Objectives: We aimed to establish biatrial and biventricular reference ranges using cardiac magnetic resonance (CMR) parameters in SCD patients without heart damage. Methods: This study compared CMR parameters, quantified by cin…
View article: Renal Findings in Patients with Thalassemia at Abdominal Ultrasound: Should We Still Talk about “Incidentalomas”? Results of a Long-Term Follow-Up
Renal Findings in Patients with Thalassemia at Abdominal Ultrasound: Should We Still Talk about “Incidentalomas”? Results of a Long-Term Follow-Up Open
We retrospectively collected all ultrasound imaging data of our thalassemia patients over a period of 10 years with the aim of assessing the prevalence and the risk factors of renal stones and cysts. Moreover, we assessed the incidence of …
View article: Photon-Counting Computed Tomography Angiography of Carotid Arteries: A Topical Narrative Review with Case Examples
Photon-Counting Computed Tomography Angiography of Carotid Arteries: A Topical Narrative Review with Case Examples Open
Photon counting computed tomography (PCCT) represents a paradigm shift from conventional CT imaging, propelled by a new generation of X-ray detectors capable of counting individual photons and measuring their energy. The first part of this…
View article: Photon-counting computed tomography in radiology
Photon-counting computed tomography in radiology Open
Photon-counting detector computed tomography (PCD-CT) devices have recently been introduced into practice, despite photon-counting detector technology having been studied for many years. PCD-CT devices are expected to provide advantages in…
View article: Magnetic Resonance Evaluation of Tissue Iron Deposition and Cardiac Function in Adult Regularly Transfused Thalassemia Intermedia Compared with Thalassemia Major Patients
Magnetic Resonance Evaluation of Tissue Iron Deposition and Cardiac Function in Adult Regularly Transfused Thalassemia Intermedia Compared with Thalassemia Major Patients Open
Objectives: This multicenter, retrospective, population-based, matched-cohort study compared clinical characteristics and magnetic resonance imaging (MRI) findings, including hepatic, pancreatic, and cardiac iron levels and cardiac functio…
View article: Technical principles, benefits, challenges, and applications of photon counting computed tomography in coronary imaging: a narrative review
Technical principles, benefits, challenges, and applications of photon counting computed tomography in coronary imaging: a narrative review Open
PCCT can significantly impact diagnostic and clinical pathways and improve the management of patients with coronary artery diseases (CADs).
View article: Neural Fields for Continuous Periodic Motion Estimation in 4D Cardiovascular Imaging
Neural Fields for Continuous Periodic Motion Estimation in 4D Cardiovascular Imaging Open
Time-resolved three-dimensional flow MRI (4D flow MRI) provides a unique non-invasive solution to visualize and quantify hemodynamics in blood vessels such as the aortic arch. However, most current analysis methods for arterial 4D flow MRI…
View article: Advanced imaging of cardiac Paraganglioma: A systematic review
Advanced imaging of cardiac Paraganglioma: A systematic review Open
In this systematic review, we aim to investigate the role of diagnostic imaging, in particular CCT, CMR, PET and SPECT in diagnosis, characterization and monitoring of cardiac PGLs.
View article: Left and right atrioventricular coupling index in patients with beta-thalassemia major
Left and right atrioventricular coupling index in patients with beta-thalassemia major Open
View article: Photon-Counting Computed Tomography in Atherosclerotic Plaque Characterization
Photon-Counting Computed Tomography in Atherosclerotic Plaque Characterization Open
Atherosclerotic plaque buildup in the coronary and carotid arteries is pivotal in the onset of acute myocardial infarctions or cerebrovascular events, leading to heightened levels of illness and death. Atherosclerosis is a complex and mult…
View article: The additive prognostic value of end-systolic pressure-volume relation by stress CMR in patients with known or suspected coronary artery disease
The additive prognostic value of end-systolic pressure-volume relation by stress CMR in patients with known or suspected coronary artery disease Open
View article: Hardware and Software Setup for Quantitative 23Na Magnetic Resonance Imaging at 3T: A Phantom Study
Hardware and Software Setup for Quantitative 23Na Magnetic Resonance Imaging at 3T: A Phantom Study Open
Magnetic resonance (MR) with sodium (23Na) is a noninvasive tool providing quantitative biochemical information regarding physiology, cellular metabolism, and viability, with the potential to extend MR beyond anatomical proton imaging. How…
View article: Potential Benefits of Photon-Counting CT in Dental Imaging: A Narrative Review
Potential Benefits of Photon-Counting CT in Dental Imaging: A Narrative Review Open
Background/Objectives: Advancements in oral imaging technology are continually shaping the landscape of dental diagnosis and treatment planning. Among these, photon-counting computed tomography (PCCT), introduced in 2021, has emerged as a …
View article: Spectral Photon-Counting Computed Tomography: Technical Principles and Applications in the Assessment of Cardiovascular Diseases
Spectral Photon-Counting Computed Tomography: Technical Principles and Applications in the Assessment of Cardiovascular Diseases Open
Spectral Photon-Counting Computed Tomography (SPCCT) represents a groundbreaking advancement in X-ray imaging technology. The core innovation of SPCCT lies in its photon-counting detectors, which can count the exact number of incoming x-ra…
View article: Oxidative Stress and Antioxidant Status in Adult Patients with Transfusion-Dependent Thalassemia: Correlation with Demographic, Laboratory, and Clinical Biomarkers
Oxidative Stress and Antioxidant Status in Adult Patients with Transfusion-Dependent Thalassemia: Correlation with Demographic, Laboratory, and Clinical Biomarkers Open
Iron overload in beta transfusion-dependent thalassemia (β-TDT) may provoke oxidative stress and reduction of the antioxidant defenses, with serious consequences for the disease course and complications. The present study evaluated the oxi…