James B. Johnson
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View article: Exploratory functional and quality of life outcomes with daily consumption of the ketone ester bis-octanoyl (R)-1,3-butanediol in healthy older adults: a randomized, parallel arm, double-blind, placebo-controlled study
Exploratory functional and quality of life outcomes with daily consumption of the ketone ester bis-octanoyl (R)-1,3-butanediol in healthy older adults: a randomized, parallel arm, double-blind, placebo-controlled study Open
Daily ingestion of 25 g of KE did not affect exploratory functional or quality-of-life end points in this pilot cohort of healthy older adults. Future work will address these endpoints as primary and secondary outcomes in a larger trial of…
View article: Can AI behave ethically during military crises? Preserving human moral agency
Can AI behave ethically during military crises? Preserving human moral agency Open
This article examines the ethical implications of integrating artificial intelligence-powered decision-support systems (AI-DSS) into strategic decision-making. As AI-DSS enhances battlefield awareness and accelerates operational tempo, it …
View article: A Randomized Open-Label, Observational Study of the Novel Ketone Ester, Bis Octanoyl (R)-1,3-Butanediol, and Its Acute Effect on ß-Hydroxybutyrate and Glucose Concentrations in Healthy Older Adults
A Randomized Open-Label, Observational Study of the Novel Ketone Ester, Bis Octanoyl (R)-1,3-Butanediol, and Its Acute Effect on ß-Hydroxybutyrate and Glucose Concentrations in Healthy Older Adults Open
Bis-octanoyl-(R)-1,3-butanediol (BO-BD) is a novel ketone ester (KE) ingredient which increases blood beta-hydroxybutyrate (BHB) concentration rapidly after ingestion. KE is hypothesized to improve function in older adults. Whilst many stu…
View article: Exploratory functional and quality of life outcomes with daily consumption of the ketone ester bis-octanoyl (R)-1,3-butanediol in healthy older adults: a randomized, parallel arm, double-blind, placebo-controlled study
Exploratory functional and quality of life outcomes with daily consumption of the ketone ester bis-octanoyl (R)-1,3-butanediol in healthy older adults: a randomized, parallel arm, double-blind, placebo-controlled study Open
Background Ketone bodies are metabolites produced during fasting or on a ketogenic diet that have pleiotropic effects on the inflammatory and metabolic aging pathways underpinning frailty in in vivo models. Ketone esters (KEs) are compound…
View article: Rationale and protocol for a safety, tolerability and feasibility randomized, parallel arm, double-blind, placebo-controlled, pilot study of a novel ketone ester targeting frailty via immunometabolic geroscience mechanisms
Rationale and protocol for a safety, tolerability and feasibility randomized, parallel arm, double-blind, placebo-controlled, pilot study of a novel ketone ester targeting frailty via immunometabolic geroscience mechanisms Open
Background Frailty is a geriatric syndrome characterized by chronic inflammation and metabolic insufficiency that creates vulnerability to poor outcomes with aging. We hypothesize that interventions which target common underlying mechanism…
View article: Daily consumption of ketone ester, bis-octanoyl (R)-1,3-butanediol, is safe and tolerable in healthy older adults, a randomized, parallel arm, double-blind, placebo-controlled, pilot study
Daily consumption of ketone ester, bis-octanoyl (R)-1,3-butanediol, is safe and tolerable in healthy older adults, a randomized, parallel arm, double-blind, placebo-controlled, pilot study Open
Objectives Ketone bodies are endogenous metabolites produced during fasting or a ketogenic diet that have pleiotropic effects on aging pathways. Ketone esters (KEs) are compounds that induce ketosis without dietary changes, but KEs have no…
View article: A randomized open-label, observational study of the novel ketone ester, bis octanoyl (R)-1,3-butanediol, and its acute effect on ß-hydroxybutyrate and glucose concentrations in healthy older adults
A randomized open-label, observational study of the novel ketone ester, bis octanoyl (R)-1,3-butanediol, and its acute effect on ß-hydroxybutyrate and glucose concentrations in healthy older adults Open
Bis-octanoyl (R)-1,3-butanediol (BO-BD) is a novel ketone ester (KE) ingredient which increases blood beta-hydroxybutyrate (BHB) concentrations rapidly after ingestion. KE is hypothesized to have beneficial metabolic effects on health and …
View article: Rationale and protocol for a safety, tolerability and feasibility randomized, parallel group, double-blind, placebo-controlled, pilot study of a novel ketone ester targeting frailty via immunometabolic geroscience mechanisms
Rationale and protocol for a safety, tolerability and feasibility randomized, parallel group, double-blind, placebo-controlled, pilot study of a novel ketone ester targeting frailty via immunometabolic geroscience mechanisms Open
Background Frailty is a geriatric syndrome characterized by chronic inflammation and metabolic insufficiency that creates vulnerability to poor outcomes with aging. We hypothesize that geroscience interventions, which target mechanisms of …
View article: The Feasibility of Monitoring Great Plains Playa Inundation with the Sentinel 2A/B Satellites for Ecological and Hydrological Applications
The Feasibility of Monitoring Great Plains Playa Inundation with the Sentinel 2A/B Satellites for Ecological and Hydrological Applications Open
Playas are ecologically and hydrologically important ephemeral wetlands found in arid and semi-arid regions of the world. Urbanization, changes in agricultural land use and irrigation practices, and climate change all threaten playas. Whil…
View article: Rhachiella malawica gen. nov., spec. nov. from Malawi—another beauty of the Afrotropics (Neuroptera: Rhachiberothidae)
Rhachiella malawica gen. nov., spec. nov. from Malawi—another beauty of the Afrotropics (Neuroptera: Rhachiberothidae) Open
A new species and a new genus of Rhachiberothidae, Rhachiella malawica gen. nov., spec. nov., are described from Malawi. The new species is characterized by a flat vertex, a long penisfilum in the male, and by a bifurcate pseudohypocauda i…
View article: Wyoming Barley Production: Opportunities to Manage Production Quality and Revenue Risks
Wyoming Barley Production: Opportunities to Manage Production Quality and Revenue Risks Open
Barley is an important crop in Wyoming that may be raised as animal feed or for malting. Different varieties are typically used for feed barley and malt barley and malting barley yields are generally lower than feed barley yields. Some far…
View article: Supplemental Revenue Assistance Payments (SURE): Montana
Supplemental Revenue Assistance Payments (SURE): Montana Open
The new Supplemental Revenue Assistance Payments Program (SURE), created by Section 12033 of the 2008 Farm Bill as an amendment to the 1994 Federal Crop Insurance Act, is a permanent disaster aid program for farms producing crops. The prog…
View article: An Introduction to Federal Crop Insurance Products for New and Beginning Wyoming Farmers and Ranchers
An Introduction to Federal Crop Insurance Products for New and Beginning Wyoming Farmers and Ranchers Open
Federal crop insurance products have been available to farmers in the United States for 80 years. Beginning in the early 1990s, the range of products offered by the USDA Risk Management Agency expanded, and today farmers have access to fed…
View article: Crop Subsidy and Crop Insurance for Wyoming Farmers in a New 2013/14 Farm Bill
Crop Subsidy and Crop Insurance for Wyoming Farmers in a New 2013/14 Farm Bill Open
Farm policy is in flux and the future of many farm subsidy programs is in question. In Congress, the Senate Agriculture Committee (and the entire Senate) and the House Agriculture Committee have recently developed alternative farm bill pro…
View article: Risk Management Options for Wyoming Ranchers
Risk Management Options for Wyoming Ranchers Open
Agricultural production is a financially risky business. On Wyoming ranches, forage losses from natural hazards (lack of moisture, severe drought, etc.) are frequent. Livestock losses also occur because of adverse winter weather, summer he…
View article: Livestock Indemnity Program (LIP): Montana
Livestock Indemnity Program (LIP): Montana Open
Disaster assistance programs were common in the 1980s, 1990s, and during several years earlier in this decade. Some were ongoing or “standing” disaster programs and others were ad hoc disaster programs.
View article: New Farm Programs in the 2014 Farm Bill: Price Loss Coverage, Agricultural Risk Coverage and the Supplemental Coverage Agricultural Insurance Option for Wyoming Farms and Ranches
New Farm Programs in the 2014 Farm Bill: Price Loss Coverage, Agricultural Risk Coverage and the Supplemental Coverage Agricultural Insurance Option for Wyoming Farms and Ranches Open
The Agricultural Act of 2014 was signed into law on February 17, 2014 by President Obama. The Act, widely referred to as the 2014 Farm Bill, introduces major changes in many U.S. farm programs that are important for farm and ranch owners a…
View article: Risk Management for Specialty Crop and Specialty Livestock Operations through Farm Service Agency Programs and Risk Management Agency Products
Risk Management for Specialty Crop and Specialty Livestock Operations through Farm Service Agency Programs and Risk Management Agency Products Open
Two questions are central to understanding producer options for risk management and other government programs related to specialty crops and specialty livestock operations. First: what is a specialty crop? Second: what is a specialty lives…
View article: Risk Management Options for Wyoming Farms
Risk Management Options for Wyoming Farms Open
Farm managers know they are involved in financially risky enterprises and, as a result, develop strategies and tools to manage that risk. Typically, those strategies involve the use of multiple production, price and business risk managemen…
View article: Production Risk Management for Wyoming Ranches: The Future for Federal Disaster Programs
Production Risk Management for Wyoming Ranches: The Future for Federal Disaster Programs Open
Wyoming ranchers know they are involved in risky enterprises and use a wide range of tools to manage risk and reduce the chances that they will suffer financial losses. As a result, they are experienced in developing and implementing risk …
View article: Risk Management for Wyoming Crop and Livestock Commodities Produced Under Organic Practices through the Use of Risk Management Agency Products and Farm Service Agency Programs
Risk Management for Wyoming Crop and Livestock Commodities Produced Under Organic Practices through the Use of Risk Management Agency Products and Farm Service Agency Programs Open
USDA organic regulations describe organic agriculture as the application of a set of cultural, biological, and mechanical practices that support the recycling of on- farm resources, promote ecological balance and conserve biodiversity. The…
View article: Nursery Crop Insurance in Wyoming
Nursery Crop Insurance in Wyoming Open
Multiple peril crop insurance for nursery production has been available since 1989 for nurseries that received at least 50 percent of their gross income from wholesale marketing of nursery plants. Multiple peril nursery crop insurance is a…
View article: Introduction to Managing Risk and Specialty and Organic Crop and Livestock Operations
Introduction to Managing Risk and Specialty and Organic Crop and Livestock Operations Open
Producers include specialty and organic crops and specialty livestock in their farm’s enterprises for many reasons. Nevertheless, over the longer term, specialty and organic crop and livestock enterprises have to be managed in ways that en…
View article: Production Risk Management for Montana Ranches: The Supplemental Federal Agricultural Disaster Programs
Production Risk Management for Montana Ranches: The Supplemental Federal Agricultural Disaster Programs Open
Montana ranchers are involved in risky enterprises and use a wide range of tools to manage risk and reduce the chances that they will suffer financial losses. They are experienced in formulating strategies for their operations and carefull…
View article: Adjusted Gross Revenue-Lite: A Whole Farm Revenue Insurance Available in Wyoming
Adjusted Gross Revenue-Lite: A Whole Farm Revenue Insurance Available in Wyoming Open
Adjusted Gross Revenue-Lite (AGR-Lite) is a federally-subsidized whole-farm revenue protection insurance plan. The plan is a whole farm (ranch) revenue insurance that covers revenue losses from most farm-raised crop commodities, animal com…
View article: Whole Farm Revenue Protection: A Crop Insurance Available in All Wyoming Counties
Whole Farm Revenue Protection: A Crop Insurance Available in All Wyoming Counties Open
Crop insurance coverage is available for 15 individual crops or crop groups in Wyoming. However, for several crops federally-subsidized insurance coverage is only available in a limited number of counties.