Barbara J. Mason
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View article: Suvorexant, an FDA-approved dual orexin receptor antagonist, reduces oxycodone self-administration and conditioned reinstatement in male and female rats
Suvorexant, an FDA-approved dual orexin receptor antagonist, reduces oxycodone self-administration and conditioned reinstatement in male and female rats Open
Background: The Department of Health and Human Services reports that prescription pain reliever (e.g., oxycodone) misuse was initiated by 4,400 Americans each day in 2019. Amid the opioid crisis, effective strategies to prevent and treat p…
View article: Preclinical and clinical evidence for suppression of alcohol intake by apremilast
Preclinical and clinical evidence for suppression of alcohol intake by apremilast Open
Treatment options for alcohol use disorders (AUDs) have minimally advanced since 2004, while the annual deaths and economic toll have increased alarmingly. Phosphodiesterase type 4 (PDE4) is associated with alcohol and nicotine dependence.…
View article: Alternative use of suvorexant (Belsomra®) for the prevention of alcohol drinking and seeking in rats with a history of alcohol dependence
Alternative use of suvorexant (Belsomra®) for the prevention of alcohol drinking and seeking in rats with a history of alcohol dependence Open
Alcohol use disorder (AUD) is one of the most treatment-resistant medical conditions globally. The orexin (Orx) system regulates diverse physiological processes, including stress, and is a system of interest for the development of pharmace…
View article: ‘After god, we give strength to each other’: young people’s experiences of coping in the context of unaccompanied forced migration
‘After god, we give strength to each other’: young people’s experiences of coping in the context of unaccompanied forced migration Open
© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/).
View article: Alcohol dependence and withdrawal increase sensitivity of central amygdalar GABAergic synapses to the glucocorticoid receptor antagonist mifepristone in male rats
Alcohol dependence and withdrawal increase sensitivity of central amygdalar GABAergic synapses to the glucocorticoid receptor antagonist mifepristone in male rats Open
Aberrant glucocorticoid signaling via glucocorticoid receptors (GR) plays a critical role in alcohol use disorder (AUD). Acute alcohol withdrawal and protracted abstinence in dependent rats are associated with increased GR signaling and ch…
View article: Looking Back, Looking Forward: Current Medications and Innovative Potential Medications to Treat Alcohol Use Disorder
Looking Back, Looking Forward: Current Medications and Innovative Potential Medications to Treat Alcohol Use Disorder Open
This article is part of a Festschrift commemorating the 50th anniversary of the National Institute on Alcohol Abuse and Alcoholism (NIAAA). Established in 1970, first as part of the National Institute of Mental Health and later as an indep…
View article: Neuropsychological performance in young adults with cannabis use disorder
Neuropsychological performance in young adults with cannabis use disorder Open
Background and Aims: Cannabis is a commonly used recreational drug in young adults. The worldwide prevalence in 18- to 25-year-olds is approximately 35%. Significant differences in cognitive performance have been reported previously for gr…
View article: The FDA-approved drug apremilast suppresses alcohol intake: clinical and pre-clinical validation
The FDA-approved drug apremilast suppresses alcohol intake: clinical and pre-clinical validation Open
Treatment options for Alcohol Use Disorders (AUD) have minimally advanced since 2004, while the annual deaths and economic toll have become alarmingly high. Bringing potential therapeutics beyond the bench and into the clinic for AUD requi…
View article: Leveraging Telehealth for Delivery of Palliative Care to Remote Communities: A Rapid Review
Leveraging Telehealth for Delivery of Palliative Care to Remote Communities: A Rapid Review Open
Background: Palliative care encompasses supportive health care for patients at any stage of illness aimed at relieving symptoms, controlling pain, managing stress, offering respite for caregivers, and optimizing the quality of life. Object…
View article: Alcohol Use Disorder: The Role of Medication in Recovery
Alcohol Use Disorder: The Role of Medication in Recovery Open
The misuse of alcohol in the United States continues to take a large toll on society, resulting in the deaths of about 88,000 Americans per year. Moreover, it is estimated that nearly 14.6 million Americans currently meet diagnostic criter…
View article: The future of translational research on alcohol use disorder
The future of translational research on alcohol use disorder Open
In March 2019, a scientific meeting was held at the University of California, Los Angeles (UCLA) Luskin Center to discuss approaches to expedite the translation of neurobiological insights to advances in the treatment of alcohol use disord…
View article: Effects of Tacrolimus and Other Immune Targeting Compounds on Binge-Like Ethanol Drinking in High Drinking in the Dark Mice
Effects of Tacrolimus and Other Immune Targeting Compounds on Binge-Like Ethanol Drinking in High Drinking in the Dark Mice Open
High Drinking in the Dark (HDID-1) mice represent a unique genetic risk model of binge-like drinking and a novel means of screening potential pharmacotherapies to treat alcohol use disorders (AUDs). We tested the effects of tacrolimus (0, …
View article: Gabapentin for the treatment of alcohol use disorder
Gabapentin for the treatment of alcohol use disorder Open
Alcohol misuse is the fifth leading risk factor for premature death and disability worldwide. Fewer than 10% of afflicted Americans receive pharmacological treatment for alcohol use disorder. Gabapentin is a calcium channel GABAergic modul…
View article: Identifying barriers to mental health help-seeking among young adults in the UK: a cross-sectional survey
Identifying barriers to mental health help-seeking among young adults in the UK: a cross-sectional survey Open
Young adults experiencing psychological distress may struggle to access help from others. Stigma and negative perceptions surrounding mental health and help-seeking may explain why young people are reluctant to approach others for help. Im…
View article: Developing clinical leadership: Trainees’ experiences and the supervisor’s role
Developing clinical leadership: Trainees’ experiences and the supervisor’s role Open
This paper describes the findings of research exploring factors which may help or hinder the development of clinical leadership among trainee clinical psychologists, and the extent to which trainees gain experience consistent with the Lead…
View article: Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals
Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals Open
Alcoholism, or alcohol use disorder, is a major public health concern that is a considerable risk factor for morbidity and disability; therefore, effective treatments are urgently needed. Here, we demonstrated that the glucocorticoid recep…
View article: Acamprosate, Alcoholism, and Abstinence
Acamprosate, Alcoholism, and Abstinence Open
Article Abstract Because this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text. Pathological alcohol use affects more than 2 billion people and accounts for nearly 6% of all deaths w…