Arjun Nair
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View article: Cross-tissue single-cell analysis reveals transcriptional and functional diversity of T follicular helper cells from infancy to adulthood 3741
Cross-tissue single-cell analysis reveals transcriptional and functional diversity of T follicular helper cells from infancy to adulthood 3741 Open
Description T follicular helper (Tfh) cells play a crucial role in humoral immunity by fine-tuning the quality of neutralizing antibodies (nAbs). However, they are mostly restricted to tissue sites, making them challenging to study in the …
View article: Geographic and Identity-Based Bias in Early-Stage Venture Capital: Implications for Inclusive Innovation in India
Geographic and Identity-Based Bias in Early-Stage Venture Capital: Implications for Inclusive Innovation in India Open
Early-stage venture capital (VC) is often portrayed as a meritocratic system, rewarding exceptional founders and transformative ideas. Yet beneath this ideal lies a persistent architecture of bias—rooted in gender, geography, and education…
View article: ReLACE: A Resource-Efficient Low-Latency Cortical Acceleration Engine
ReLACE: A Resource-Efficient Low-Latency Cortical Acceleration Engine Open
We present a Cortical Neural Pool (CNP) architecture featuring a high-speed, resource-efficient CORDIC-based Hodgkin Huxley (RCHH) neuron model. Unlike shared CORDIC-based DNN approaches, the proposed neuron leverages modular and performan…
View article: Formally Exploring Time-Series Anomaly Detection Evaluation Metrics
Formally Exploring Time-Series Anomaly Detection Evaluation Metrics Open
Undetected anomalies in time series can trigger catastrophic failures in safety-critical systems, such as chemical plant explosions or power grid outages. Although many detection methods have been proposed, their performance remains unclea…
View article: Differentiating clinically important interstitial lung abnormalities in lung cancer screening
Differentiating clinically important interstitial lung abnormalities in lung cancer screening Open
Background Interstitial lung abnormalities (ILAs) are common incidental findings in lung cancer screening (LCS). However, challenges remain in identifying clinically relevant ILAs as highlighted in a joint statement by a European multidisc…
View article: ESR Essentials: lung cancer screening with low-dose CT—practice recommendations by the European Society of Thoracic Imaging
ESR Essentials: lung cancer screening with low-dose CT—practice recommendations by the European Society of Thoracic Imaging Open
Low-dose CT screening for lung cancer reduces the risk of death from lung cancer by at least 21% in high-risk participants and should be offered to people aged between 50 and 75 with at least 20 pack-years of smoking. Iterative reconstruct…
View article: A basophil-fibroblast pro-inflammatory axis fuels type 2 skin inflammation
A basophil-fibroblast pro-inflammatory axis fuels type 2 skin inflammation Open
View article: Unmasking the Masquerader: A Case of Tropical Pulmonary Eosinophilia-mimicking Tuberculosis
Unmasking the Masquerader: A Case of Tropical Pulmonary Eosinophilia-mimicking Tuberculosis Open
View article: Performance of volume and diameter thresholds in malignancy prediction of solid nodules in lung cancer screening
Performance of volume and diameter thresholds in malignancy prediction of solid nodules in lung cancer screening Open
Background Prospective validation and comparison of the performance of nodule management protocols is limited. The aim of this study was to examine the performance of size and risk thresholds for assessing malignancy in solid nodules at ba…
View article: Neuroimaging informatics framework for analyzing rare brain metastasis patterns in pleural mesothelioma using hybrid PET CT
Neuroimaging informatics framework for analyzing rare brain metastasis patterns in pleural mesothelioma using hybrid PET CT Open
A rare and hostile cancer mostly affecting the lungs, pleural mesothelioma has an exceedingly unusual but clinically relevant propagation to the brain. Their unusual appearance and low frequency make early diagnosis and accurate characteri…
View article: A Serendipitous Histopathological Revelation: An Intriguing Case Report of a Cystic Schwannoma of the Lateral Neck
A Serendipitous Histopathological Revelation: An Intriguing Case Report of a Cystic Schwannoma of the Lateral Neck Open
View article: Impact of Low-Dose Computed Tomography Findings on Cigarette Smoking Cessation Among High-Risk Adults Participating in Lung Cancer Screening
Impact of Low-Dose Computed Tomography Findings on Cigarette Smoking Cessation Among High-Risk Adults Participating in Lung Cancer Screening Open
Introduction Integrating effective smoking cessation strategies for individuals undergoing lung cancer screening stands to significantly increase the impact of lung screening programmes. We assessed the impact of low-dose computed tomograp…
View article: Incidence rate and malignancy risk in new nodules in a lung cancer screening programme
Incidence rate and malignancy risk in new nodules in a lung cancer screening programme Open
View article: Low-dose CT for lung cancer screening in a high-risk population (SUMMIT): a prospective, longitudinal cohort study
Low-dose CT for lung cancer screening in a high-risk population (SUMMIT): a prospective, longitudinal cohort study Open
GRAIL.
View article: Mindfulness-based Therapies and Cancer-related Fatigue: A Narrative Review
Mindfulness-based Therapies and Cancer-related Fatigue: A Narrative Review Open
Globally, the prevalence of cancer is steadily increasing, making it the second most common cause of death from non-communicable diseases, after cardiovascular disorders. It represents the highest rates of morbidity and mortality, and its …
View article: Improving uptake of lung cancer screening: an observational study on the impact of timed appointments and reminders
Improving uptake of lung cancer screening: an observational study on the impact of timed appointments and reminders Open
Lung cancer screening (LCS) reduces lung cancer-related mortality; however, uptake remains low compared with other cancer screening programmes. In this observational study, we report the impact of timed appointments and reminders on partic…
View article: Federated Learning for Multi-Modal Health Data Integration: Enhancing Diagnostic Accuracy and Ensuring Data Privacy
Federated Learning for Multi-Modal Health Data Integration: Enhancing Diagnostic Accuracy and Ensuring Data Privacy Open
The healthcare sector is experiencing a surge in diverse health data, encompassing medical imaging, electronic health records and live sensor readings from wearable technology. Integrating these multi-modal datasets holds immense potential…
View article: The Impact of Anuloma Viloma Pranayama on Pulmonary Function in Individuals with Reduced Lung Reserve Post-COVID-19: A Narrative Review
The Impact of Anuloma Viloma Pranayama on Pulmonary Function in Individuals with Reduced Lung Reserve Post-COVID-19: A Narrative Review Open
Objective: The primary objective of this literature review was to investigate the effects of Anuloma Viloma Pranayama (AVP) on individuals with reduced lung reserve resulting from COVID-19. Introduction: The COVID-19 pandemic has emerged a…
View article: A randomized multi-arm open labelled comparative clinical trial report of Pankajakasthuri DiabetEaze powder, a novel polyherbal formulation on the nutritional management and glycemic control in type 2 diabetic and prediabetic patients
A randomized multi-arm open labelled comparative clinical trial report of Pankajakasthuri DiabetEaze powder, a novel polyherbal formulation on the nutritional management and glycemic control in type 2 diabetic and prediabetic patients Open
CTRI/2021/04/032956 on 20/04/2021.
View article: EVALUATING THE ROLE OF MOOLABANADHA IN TREATING HAEMORRHOIDS AND ASSOCIATED GASTROENTEROLOGICAL CONDITIONS: A NARRATIVE REVIEW
EVALUATING THE ROLE OF MOOLABANADHA IN TREATING HAEMORRHOIDS AND ASSOCIATED GASTROENTEROLOGICAL CONDITIONS: A NARRATIVE REVIEW Open
Objective:The primary objective of this narrative review was to evaluate the efficacy of yoga therapy in managing symptoms in individuals with haemorrhoids. Introduction:Haemorrhoids are defined as the symptomatic engorgement or downward d…
View article: <div> POVERTY DYNAMICS: Exploring the&nbsp;<span>Relationship&nbsp;</span><span>between Urbanisation&nbsp;</span><span>and Poverty</span></div>
POVERTY DYNAMICS: Exploring the <span>Relationship </span><span>between Urbanisation </span><span>and Poverty</span> Open
View article: Correction to: Advancing Multi-modal Visual Pattern Recognition: Object Detection
Correction to: Advancing Multi-modal Visual Pattern Recognition: Object Detection Open
View article: Protocol for a systematic review and individual participant data meta-analysis for risk factors for lung cancer in individuals with lung nodules identified by low-dose CT screening
Protocol for a systematic review and individual participant data meta-analysis for risk factors for lung cancer in individuals with lung nodules identified by low-dose CT screening Open
Background Worldwide, lung cancer (LC) is the second most frequent cancer and the leading cause of cancer related mortality. Low-dose CT (LDCT) screening reduced LC mortality by 20–24% in randomised trials of high-risk populations. A signi…
View article: Future of Natural Language Processing (Human Like Conversation)
Future of Natural Language Processing (Human Like Conversation) Open
Natural language processing (NLP) has revolutionized artificial intelligence by solving the challenge of enabling machines to understand, interpret, and reproduce human language. The importance of NLP lies in its applications in many areas…
View article: Spinal cord–spinal canal disproportion following treatment for syringomyelia associated with Chiari malformation type I: illustrative case
Spinal cord–spinal canal disproportion following treatment for syringomyelia associated with Chiari malformation type I: illustrative case Open
BACKGROUND Chiari malformation type I (CM-I) is a common pediatric neurosurgical condition that is often associated with syringomyelia (SM) and spine deformity. The association of these three conditions is well recognized, but the pathophy…
View article: Relevance of species-specific procalcitonin (PCT) and C-reactive protein (CRP) as clinical biomarkers in goat pneumonia
Relevance of species-specific procalcitonin (PCT) and C-reactive protein (CRP) as clinical biomarkers in goat pneumonia Open
Pneumonia is a leading cause of economic losses in the ruminant industry throughout the world. This study aimed to determine the relevance of species-specific procalcitonin (PCT) and C-reactive protein (CRP) as clinical biomarkers in goat …
View article: Creating a Safer World for Children, Solutions and Partnerships Social Workers Rolein Protecting Girl Children from Sexual Exploitation and Abuse
Creating a Safer World for Children, Solutions and Partnerships Social Workers Rolein Protecting Girl Children from Sexual Exploitation and Abuse Open
Child sexual abuse is a prevalent and devastating issue in India, with 28.9% of children experiencing some form of sexual crime. However, justice is often denied to child victims due to inadequacies in India’s justice delivery system. This…
View article: Enhancing cancer prediction in challenging screen-detected incident lung nodules using time-series deep learning
Enhancing cancer prediction in challenging screen-detected incident lung nodules using time-series deep learning Open
Lung cancer screening (LCS) using annual computed tomography (CT) scanning significantly reduces mortality by detecting cancerous lung nodules at an earlier stage. Deep learning algorithms can improve nodule malignancy risk stratification.…
View article: Predicting histopathological features of aggressiveness in lung cancer using CT radiomics: a systematic review
Predicting histopathological features of aggressiveness in lung cancer using CT radiomics: a systematic review Open
Due to the high risk of bias and concerns regarding applicability, the evidence is inconclusive as to whether radiomic features can accurately predict prognostically important histopathological features of cancer aggressiveness. Many studi…
View article: Reported case of recurrence of fever in a patient with multisystem inflammatory syndrome in children due to COVID-19 infection after initial successful treatment
Reported case of recurrence of fever in a patient with multisystem inflammatory syndrome in children due to COVID-19 infection after initial successful treatment Open