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View article: Resilience in Bipolar Disorder Compared to Clinical and Non‐Clinical Populations: A Systematic Review and Meta‐Analysis
Resilience in Bipolar Disorder Compared to Clinical and Non‐Clinical Populations: A Systematic Review and Meta‐Analysis Open
Introduction Resilience is present in both clinical and non‐clinical populations; yet, there is a paucity of literature examining its role in bipolar disorder (BD). The goal of the present systematic review and meta‐analysis was to substan…
View article: The role of predominant polarity in older age bipolar disorder
The role of predominant polarity in older age bipolar disorder Open
PP classification distinguishes meaningful clinical and cognitive subgroups in OABD. The UPP subgroup associates with greater illness severity and functional impairment. These findings support the integration of PP into personalized treatm…
View article: Influence of Sex and Diagnosis on Clinical Variables and Neurocognitive Performance in Severe Mental Illness. Results From the <scp>PsyCourse</scp> Study
Influence of Sex and Diagnosis on Clinical Variables and Neurocognitive Performance in Severe Mental Illness. Results From the <span>PsyCourse</span> Study Open
Introduction Bipolar disorder (BD) and schizophrenia (SZ) are serious mental illnesses (SMI) with overlapping symptoms but distinct differences in onset and course. Sex differences are an area of growing interest in SMI. This study aims to…
View article: Intraparietal sulcus depth is associated with negative symptomatology in patients with first-episode psychosis
Intraparietal sulcus depth is associated with negative symptomatology in patients with first-episode psychosis Open
The study of brain morphology parameters in patients with first-episode psychosis (FEP) could help detect early brain footprints related to this disease and its predominant symptomatology. We examined gray matter (GM) volume, cortical thic…
View article: Mind the gap: The impact of discrepancy between current cognitive function and premorbid intelligence on psychosocial functioning in older age bipolar disorder
Mind the gap: The impact of discrepancy between current cognitive function and premorbid intelligence on psychosocial functioning in older age bipolar disorder Open
IQ-cognition discrepancy may serve as a useful idiographic marker of functional impairment in OABD, particularly for individuals with high premorbid IQ. Its use could enhance clinical decision-making and broaden inclusion in pro-cognitive …
View article: Comparing cognitive reserve between patients with bipolar disorder, other psychiatric disorders and healthy controls: a systematic review and multilevel meta-analysis
Comparing cognitive reserve between patients with bipolar disorder, other psychiatric disorders and healthy controls: a systematic review and multilevel meta-analysis Open
CR is lower in BD compared to HCs, suggesting its contribution to cognitive and functional impairments. Conversely, similar CR between BD and MDD highlight shared clinical vulnerabilities. These results underscore the need for targeted int…
View article: Therapist's Assessment of Their Patient's Session‐Level Emotional Processes: Validation of the In‐Session Patient Affective Reactions Questionnaire–Clinician Form
Therapist's Assessment of Their Patient's Session‐Level Emotional Processes: Validation of the In‐Session Patient Affective Reactions Questionnaire–Clinician Form Open
Background The current study aimed to evaluate a therapist version of the in‐Session Patient Affective Reactions Questionnaire (SPARQ). The SPARQ was developed to assess a pattern of emotions, thoughts, and behaviors experienced by a patie…
View article: Efficacy of psychosocial interventions on social functioning in individuals with childhood maltreatment experiences: a protocol for a systematic review and network meta-analysis
Efficacy of psychosocial interventions on social functioning in individuals with childhood maltreatment experiences: a protocol for a systematic review and network meta-analysis Open
Background: Several psychosocial interventions have shown promising effects in treating people affected by childhood maltreatment (CM); however, their comparative efficacy on social functioning remains largely unknown. To address this issu…
View article: Bipolar II disorder: a state‐of‐the‐art review
Bipolar II disorder: a state‐of‐the‐art review Open
Bipolar II disorder (BD‐II) is currently identified by both the DSM‐5 and ICD‐11 as a distinct subtype of bipolar disorder, defined by at least one depressive episode and at least one hypomanic episode, with no history of mania. Despite it…
View article: Predominant Polarity for Enhanced Phenotyping and Personalized Treatment of Bipolar Disorder: A Narrative Review on Recent Findings
Predominant Polarity for Enhanced Phenotyping and Personalized Treatment of Bipolar Disorder: A Narrative Review on Recent Findings Open
Purpose of Review This paper explores Predominant Polarity (PP) in Bipolar Disorder (BD), defined as the predominance of either manic or depressive episodes over a patient’s course of illness. We examine its clinical relevance, neurobiolog…
View article: Neurocognitive and psychosocial functioning profiles in bipolar disorder and comorbid attention deficit hyperactivity disorder: A systematic review and meta-analysis
Neurocognitive and psychosocial functioning profiles in bipolar disorder and comorbid attention deficit hyperactivity disorder: A systematic review and meta-analysis Open
Bipolar disorder (BD) and attention deficit hyperactivity disorder (ADHD) are chronic psychiatric conditions with significant impacts on neurocognitive and psychosocial functioning. Co-occurrence of BD and ADHD (BD-ADHD) presents unique cl…
View article: Impact of Bipolar Disorder Increased White Matter Hyperintensities on White Matter Connectivity
Impact of Bipolar Disorder Increased White Matter Hyperintensities on White Matter Connectivity Open
Background Individuals with bipolar disorder have been reported to have increased white matter hyperintensities (WMH) in fluid‐attenuated inversion recovery (FLAIR) magnetic resonance scans. However, it is unknown whether this WMH increase…
View article: Sex differences in psychosocial functioning and neurocognition in bipolar disorder: a systematic review and meta-analysis
Sex differences in psychosocial functioning and neurocognition in bipolar disorder: a systematic review and meta-analysis Open
Introduction Impairment in both psychosocial functioning and neurocognition (NC) performance is present in bipolar disorder (BD) yet the role of sex differences in these deficits remains unclear. The present systematic review and meta-anal…
View article: Contrasting genetic burden for bipolar disorder: Early onset versus late onset in an older adult bipolar disorder sample
Contrasting genetic burden for bipolar disorder: Early onset versus late onset in an older adult bipolar disorder sample Open
Older Adults with Bipolar Disorder (OABD) represent a heterogeneous group, including those with early and late onset of the disorder. Recent evidence shows both groups have distinct clinical, cognitive, and medical features, tied to differ…
View article: Facing Life in Old Age: Exploring Resilience in Older Adults with Bipolar Disorder
Facing Life in Old Age: Exploring Resilience in Older Adults with Bipolar Disorder Open
Background: Older adults with bipolar disorder (OABD) are individuals aged 50 years and older with bipolar disorder (BD). People with BD may have fewer coping strategies or resilience. A long duration of the disease, as seen in this popula…
View article: Facing Life in Old Age: Exploring Resilience in Older Adults with Bipolar Disorder
Facing Life in Old Age: Exploring Resilience in Older Adults with Bipolar Disorder Open
Background: Older adults with bipolar disorder (OABD) are individuals aged 50 years and older with bipolar disorder (BD). People with BD may have fewer coping strategies or resilience. A long course of the disease, such as in OABD, could i…
View article: Sex differences in neurocognitive performance in older adults with bipolar disorder
Sex differences in neurocognitive performance in older adults with bipolar disorder Open
Introduction In recent years, research has focused on the older adults with bipolar disorder (OABD), aged 50 years and over, a constantly growing population due to the increased of life expectancy. Actually, some authors suggest that these…
View article: Cognitive reserve in Older Adults with Bipolar Disorder and its relationship with cognitive performance and psychosocial functioning
Cognitive reserve in Older Adults with Bipolar Disorder and its relationship with cognitive performance and psychosocial functioning Open
Introduction Cognitive reserve (CR) refers to the ability of the brain to cope with damage or pathology. In bipolar disorder (BD), it has been seen that the effects of the disease may potentially reduce CR, thus compromising cognitive outc…
View article: Study protocol – elucidating the neural correlates of functional remediation for older adults with bipolar disorder
Study protocol – elucidating the neural correlates of functional remediation for older adults with bipolar disorder Open
Introduction Beyond mood abnormalities, bipolar disorder (BD) includes cognitive impairments that worsen psychosocial functioning and quality of life. These deficits are especially severe in older adults with BD (OABD), a condition expecte…
View article: Predictors of Functional Impairment in Bipolar Disorder: Results From 13 Cohorts From Seven Countries by the Global Bipolar Cohort Collaborative
Predictors of Functional Impairment in Bipolar Disorder: Results From 13 Cohorts From Seven Countries by the Global Bipolar Cohort Collaborative Open
The bipolar clinical research community is poised to work together to characterize the multi-dimensional contributors to impairment and address the barriers that impede patients' complete recovery. We must also identify the core features w…
View article: Long-term outcome predictors after functional remediation in patients with bipolar disorder – CORRIGENDUM
Long-term outcome predictors after functional remediation in patients with bipolar disorder – CORRIGENDUM Open
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View article: Mindfulness, Attention, and Impulsivity in Bipolar Disorder
Mindfulness, Attention, and Impulsivity in Bipolar Disorder Open
Introduction Bipolar disorder (BD) is a chronic mental disorder characterized by mood instability 1 . BD is further related to neurocognitive and functional disruptions that remain remarkably stable even when patients are euthymic, leading…
View article: Vickybot, a Chatbot for Anxiety-Depressive Symptoms and Work-Related Burnout in Primary Care and Health Care Professionals: Development, Feasibility, and Potential Effectiveness Studies
Vickybot, a Chatbot for Anxiety-Depressive Symptoms and Work-Related Burnout in Primary Care and Health Care Professionals: Development, Feasibility, and Potential Effectiveness Studies Open
Background Many people attending primary care (PC) have anxiety-depressive symptoms and work-related burnout compounded by a lack of resources to meet their needs. The COVID-19 pandemic has exacerbated this problem, and digital tools have …