Explanipedia

Immediate breastfeeding and skin-to-skin contact as a physiological approach to third-stage labour management: an observational study Open

Ruchika Gupta, Sanjeev Kishore · 2025

Background: The third stage of labour is critical for preventing postpartum haemorrhage and ensuring maternal and neonatal safety. Early initiation of breastfeeding combined with immediate skin-to-skin contact (SSC) may enhance physiologic…

A178 DISEASE COURSE AND MANAGEMENT OF CHILDREN WITH VERY EARLY ONSET INFLAMMATORY BOWEL DISEASE Open

Sanjeev Kishore, Aruna Sethuraman, H Binomar, Kevan Jacobson · 2025

Background Very early-onset inflammatory bowel disease (VEO-IBD), defined as IBD diagnosed before 6 years of age, has a distinct phenotype with predominantly colonic involvement. However, there are limited studies describing the long-term …

Role of Contrast Perfusion Weighted Magnetic Resonance Imaging in Grading of Brain Tumors with Histopathological Correlation Open

Vikrant Bardhan, Pankaj Sharma, Rajnish Arora, Sanjeev Kishore · 2024

Background: Traditional MRI sequences provide precise anatomical information about brain tumors. But these sequences can’t quantitatively evaluate vascular physiology, or capture tumor biology at the molecular level; which is important for…

Altering Trends in Pathological Spectrum of Cholecystectomy Specimen: Time to be More Vigilant Open

Vinay N. Gowda, Arvind Kumar, Ashok Singh, Prashant Durgapal, Amit Gupta , et al. · 2024

Background: Gall bladder cancer is a rare, most common and aggressive malignancy of the biliary tree, accounting for 80%–90% of biliary tract cancers. Gallstones are one of the major causes of the development of cholecystitis and long-term…

Differences in the Expression of Autophagy Markers Microtubule-Associated Protein Light Chains 3A and 3B in Oral Premalignant Lesions and Oral Squamous Cell Carcinoma: A Cross-Sectional Study Open

Tulika Wakhloo, Prashant Durgapal, Nilotpal Chowdhury, Srinivas H. Reddy, Ashi Chug , et al. · 2024

Multifaceted Roles of 14-3-3 Proteins in Biological Processes: From Insect Physiology to Human Diseases Open

A S Brijesh, Nikhil Reddy K S, A Hemavathi, Sanjeev Kishore, Shalini K. S · 2024

14-3-3 proteins are ubiquitous-sticky functional regulatory molecules entails for exerting an array of biological phenomenal processes across eukaryotes, including insects. They mainly execute their role by binding with specific targets of…

Incidentally Detected Myocardial Bridging of the Left Circumflex Coronary Artery in a Young Male Open

Aditi Dixit, Vikas Vaibhav, Raviprakash Meshram, Sanjeev Kishore, Ravi Hari Phulware · 2024

INTRODUCTION Myocardial bridging (MB) is known to be usually present since birth but generally manifests in the 20–30 years' age group and has an association with physical exertion.[1,2] The phenomenon of the intramyocardial course of the …

Comparing Four Different Risk Malignancy Indices in Differentiating Benign and Malignant Ovarian Masses Open

Rajlaxmi Mundhra, Anupama Bahadur, Jyotshna Kashibhatla, Sanjeev Kishore, Jaya Chaturvedi · 2024

A BSTRACT Background: Accurate prediction of ovarian masses preoperatively is crucial for optimal management of ovarian cancers. Objective: The objective of this study was to identify the risk of malignancy index (RMI) incorporating menopa…

The Relationship of Grade, Stage and Tobacco Usage in Head and Neck Squamous Cell Carcinoma With p53, PIK3CA and MicroRNA Profiles Open

Kamini Kiran, Nilotpal Chowdhury, Ashok Singh, Manu Malhotra, Sanjeev Kishore · 2024

Through the deciphering of complex miRNA patterns and their relationships with clinicopathology, this study attempted to increase our understanding of HNSCC. Some candidate miRNAs showing probable association with grade, stage and personal…

Embryonal rhabdomyosarcoma of the prostate: Clinico-pathological highlights with review of literature Open

Anshima Singh, Ravi Hari Phulware, Arvind Kumar, Sanjeev Kishore · 2024

Rhabdomyosarcoma (RMS) is the third most common extra-cranial sarcoma occurring in childhood, adolescents, and young adults (AYAs); and is rare in adults. Literature about RMS mainly considers RMS in AYAs, either with that in the children …

A Study of Ki-67 Immunostaining in Prostate Carcinomas and Its Correlation with Gleason’s Score and Prognosis: An Experience at a Tertiary Centre in the Himalayan Foothills Open

Nishi Jha, Ravi Hari Phulware, Arvind Kumar, Ashok Singh, Prashant Durgapal , et al. · 2024

Unravelling the role of autophagy in human dental pulp Open

Tulika Wakhloo, Sanjeev Kishore, Prashant Durgapal · 2024

Autophagy is an evolutionarily conserved intracellular catabolic process that recycles and degrades proteins, organelles and pathogens. It is an endogenous defence mechanism regulating multiple cellular pathways like apoptosis, inflammatio…

Actinomycotic osteomyelitis of maxillary sinus and hard palate in a post-COVID-19 patient Open

Anshima Singh, Ravi Hari Phulware, Arvind Kumar, Alok Kumar, Sanjeev Kishore · 2023

Cytomorphological Features of Complex Fibroadenoma Breast Open

Ravi Hari Phulware, Samikshya Thapa, Arvind Kumar, Sanjeev Kishore · 2023

Dear Editor, Fibroadenomas are the most common solid benign breast lesions in women having epithelial and stromal components. It may occur at any age, with the peak incidence being in adolescent girls around their 20s and 30s, except for c…

Histopathological Spectrum of Leiomyoma of the Uterus with an Emphasis on Pathological Technique to Avoid the Misdiagnosis: A Single Tertiary Centre Experience Open

Suman Kumari, Gajendra Kumar Yadav, Bhoomika Kaushik, Arvind Kumar, Ravi Hari Phulware , et al. · 2023

Background: The most typical uterine tumour that develops from smooth muscle is a leiomyoma. It might be challenging to provide an accurate diagnosis when it exhibits abnormal gross features or artefacts. The fixation, grossing, taking sec…

Comparison of Human Epididymis Protein 4, Cancer Antigen 125, and Ultrasound Prediction Model in Differentiating Benign from Malignant Adnexal Masses Open

Anupama Bahadur, Namrata Bhattacharya, Rajlaxmi Mundhra, Kavita Khoiwal, Latika Chawla , et al. · 2023

Background: This study aimed to compare the diagnostic performance of carcinogenic antigen (CA) 125, (HE)-4 (Human epididymis protein 4), and ultrasound (International Ovarian Tumor Analysis [IOTA]) Simple Rules individually and to derive …

Proliferating Trichilemmal Tumor of Scalp—An Eye Opener for a Pathologist Open

Bhoomika Kaushik, Shweta Azad, Arvind Kumar, Sanjeev Kishore · 2023

Proliferating trichilemmal tumor is a rare tumor of external root sheath of hair follicles, originating mainly from the scalp of middle-aged females. Grossly and microscopically, it mimics squamous cell carcinoma; hence, it is important to…

Expression of ER, PR, and HER-2 Neu and correlation with tumor markers in gall bladder carcinoma Open

Rishit Mani, Amit Gupta, Sweety Gupta, Bela Goyal, Rahul Mishra , et al. · 2023

Background: Females having a large proportion of gallbladder carcinoma (GBC) and a higher incidence of gallstones pointed toward the role of sex hormones in GBC development. In this study, we evaluated the expression of Estrogen receptor (…

Epidermoid cyst: An esthetic challenge, if neglected—A comprehensive analysis of 217 cases Open

Bhagyshree Singh, Ravi Hari Phulware, Pakesh Baishya, Ashok Singh, Prashant Durgapal , et al. · 2023

The findings suggest that fine-needle aspiration can be used as a quick diagnostic test even in remote areas by the general practitioner who can send the slides for evaluation to a pathologist. Many times, clinically looking epidermoid cys…

An adding up of an exceptionally rare case report: Primary Squamous cell carcinoma of Jejunum from North India Open

Arvind Kumar, Divya Singh, Vinay N. Gowda, Rishabh Sahai, Sudhir Kumar , et al. · 2023

Squamous cell carcinoma (SCC) of lower gastrointestinal tract is a rare tumor and duodenum is the most common site of involvement. In addition, involvement of jejunum by SCC is further exceptionally rare, and only nominal cases are present…

Primary Malignant Melanoma of the Oral Cavity: A Retrospective Study From a Tertiary Care Centre of North India Open

Kavya Udyavar Raviraj, Sonali Mishra, Aishwarya Chandra, Anupa Khanal, Nishi Jha , et al. · 2022

Efficacy of Ferulic Acid in an Animal Model of Drug-Resistant Epilepsy: Beneficial or Not? Open

Surabhi Thapliyal, Jagjit Singh, Mukesh Mamgain, Ashish Kumar, Manisha Bisht , et al. · 2022

Background Lamotrigine (LTG) and subconvulsive doses of pentylenetetrazol (PTZ) as a model mimic drug-resistant epilepsy (DRE), which is a serious unmet medical condition. Previous evidence suggests an imperative role of neuroinflammation …

A Clinicopathological Correlation of Bladder Cancer in Young and Old Patients: Our Experience and Review of Literature Open

Harkirat Singh Talwar, Vikas Kumar Panwar, Ankur Mittal, Sanjeev Kishore, Arup Kumar Mandal · 2022

Clinical and Biochemical Correlation With Cytomorphological Findings of Lymphocytic Thyroiditis: An Experience at a Tertiary Centre in the Himalayan Foothills Open

Monika Singh, Suman Kumari, Bhoomika Kaushik, Arvind Kumar, Ashok Singh , et al. · 2022

Introduction Lymphocytic thyroiditis is an autoimmune disorder and one of the major causes of hypothyroidism. On cytomorphology, it is characterized by follicular destruction by lymphocytes with elevated biochemical markers, including a pa…

When to Avoid a Restaging Procedure for Non-muscle Invasive Bladder Cancer? Inferences from a Tertiary Care Center Open

Deepak Prakash Bhirud, Ankur Mittal, Sunil Kumar, Tushar Aditya Narain, Sanjeev Kishore , et al. · 2022

Collecting Duct Carcinoma of the Kidney – A Clinicopathological Overview Open

Pakesh Baishya, Ravi Hari Phulware, Sanjeev Kishore, Ankur Mittal, Pankaj Sharma · 2022

Karyoanomalic frequency assay during radiation therapy – A promising marker in the prognosis of oral and oropharyngeal carcinoma Open

K. Ravi, Pushpa N.B., Sanjeev Kishore, Sohinder Kaur, Vandana Mehta , et al. · 2021

Introduction: Radiotherapy is commonly used in the treatment of oral and oropharyngeal carcinomas, either alone or in combination with other modalities of treatment like surgery/chemotherapy. It is always essential to know the nature of tu…

Immunoexpression of PD-L1 and PD-1 and Its Clinicopathological Correlation in Urothelial Carcinomas Open

Utpal Kumar, Michael Leonard Anthony, Rishabh Sahai, Ankur Mittal, Prashant Durgapal , et al. · 2021

Introduction Urothelial carcinomas are the most common types of bladder tumors that have recently shown a changing trend in treatment protocols with the introduction and approval of immune checkpoint inhibitors. The most important immune c…

Haematological and Biochemical Predictors of Bone Marrow Metastases in Non-Haematological Malignancies Open

Shruti Agrawal, Rekha Bhandari, Vinay N. Gowda, Amit Gupta, Neha Singh , et al. · 2021

Background: Bone marrow metastasis is an uncommon yet significant presentation of many non haematological malignancies. Aims: The present study was conducted with the aim of analysing the clinical, haematological and biochemical parameters…

An Unusual Cause of Cholestasis in an Infant: Biliary Atresia Type IIB Open

Poonam Sherwani, Rishi Bolia, Ashish Kaushik, Sumit Kumar, Sanjeev Kishore , et al. · 2021

Biliary atresia (BA) is a progressive destructive cholangiopathy of unknown etiology that presents in early infancy. It has a worldwide frequency of 1:8,000–1:15,000 and is common in Asia than in the west. Based on the level at which the l…

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