Explanipedia

673 Improving cystic fibrosis clinic efficiency: a quality improvement project arising from patient experience data Open

O. Ries, Hillary Bashaw, B. Timothy Baxter, Kate H. Bentley, A. Reyes Bueno , et al. · 2023

Effect of Doxycycline on Progression of Arterial Calcification in the Noninvasive Treatment of Abdominal Aortic Aneurysm Clinical Trial (N-TA(3)CT) Open

Tanner I. Kim, Valentyna Kostiuk, Sydney L. Olson, John A. Curci, Jon S. Matsumura , et al. · 2023

Aortic Calcification Is Associated with Decreased Abdominal Aortic Aneurysm Growth Open

Sydney L. Olson, Tanner I. Kim, Valentyna Kostiuk, John A. Curci, Jon S. Matsumura , et al. · 2023

Effect of Two Years of Doxycycline Treatment on Infrarenal Aortic Neck Diameter Open

Annalise M. Panthofer, Sydney L. Olson, Brooks L. Rademacher, Larry W. Kraiss, William Blackwelder , et al. · 2023

Doxycycline does not demonstrate infrarenal aortic neck growth stabilisation in small AAA followed for two years by thin cut CT imaging using a standardised acquisition protocol and cannot be recommended for mitigation of growth of the aor…

The effect of diabetes on abdominal aortic aneurysm growth over 2 years Open

Matthew Nordness, B. Timothy Baxter, Jon S. Matsumura, Michael L. Terrin, Kevin Zhang , et al. · 2021

120: A pediatric QI project to improve lung function and optimize treatment of CF pulmonary exacerbations Open

Sydney Schiff, S. Pendley, B. Timothy Baxter, Miah Starks, K. S. Krikorian , et al. · 2021

Role of volume in small abdominal aortic aneurysm surveillance Open

Sydney L. Olson, Annalise M. Panthofer, William C. Blackwelder, Michael L. Terrin, John A. Curci , et al. · 2021

Role of Volume in Small Abdominal Aortic Aneurysm Surveillance Open

Sydney L. Olson, Annalise M. Panthofer, William Blackwelder, Michael Terrin, John A. Curci , et al. · 2021

Evaluating Growth Patterns of Abdominal Aortic Aneurysm Diameter With Serial Computed Tomography Surveillance Open

Sydney L. Olson, Marniker Wijesinha, Annalise M. Panthofer, William C. Blackwelder, Gilbert R. Upchurch , et al. · 2021

ClinicalTrials.gov Identifier: NCT01756833.

Enhanced Notch3 signaling contributes to pulmonary emphysema in a Murine Model of Marfan syndrome Open

Kathryn Jespersen, Zhibo Liu, Chenxin Li, Paul G.R. Harding, Kylie Sestak , et al. · 2020

Marfan syndrome (MFS) is a heritable disorder of connective tissue, caused by mutations in the fibrillin-1 gene. Pulmonary functional abnormalities, such as emphysema and restrictive lung diseases, are frequently observed in patients with …

Effect of Doxycycline on Aneurysm Growth Among Patients With Small Infrarenal Abdominal Aortic Aneurysms Open

B. Timothy Baxter, Jon S. Matsumura, John A. Curci, Ruth McBride, LuAnn Larson , et al. · 2020

ClinicalTrials.gov Identifier: NCT01756833.

Ex vivo expansion of regulatory T cells from abdominal aortic aneurysm patients inhibits aneurysm in humanized murine model Open

Melissa Suh, Rishi Batra, Jeffrey S. Carson, Wanfen Xiong, Matthew Dale , et al. · 2020

CD95-ligand contributes to abdominal aortic aneurysm progression by modulating inflammation Open

Zhibo Liu, Matthew P. Fitzgerald, Trevor Meisinger, Rishi Batra, Melissa Suh , et al. · 2018

These studies demonstrated that inflammatory cell infiltration during AAA formation is dependent on CD95L from myelogeous cells. Aneurysm inhibition by deletion of CD95L is mediated in part by down-regulation of caspase 8.

Elastin-Derived Peptides Promote Abdominal Aortic Aneurysm Formation by Modulating M1/M2 Macrophage Polarization Open

Matthew Dale, Wanfen Xiong, Jeffrey S. Carson, Melissa Suh, Andrew Karpisek , et al. · 2016

Abdominal aortic aneurysm is a dynamic vascular disease characterized by inflammatory cell invasion and extracellular matrix degradation. Damage to elastin in the extracellular matrix results in release of elastin-derived peptides (EDPs), …

Non-invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial (N-TA 3 CT): Design of a Phase IIb, placebo-controlled, double-blind, randomized clinical trial of doxycycline for the reduction of growth of small abdominal aortic aneurysm Open

B. Timothy Baxter, Jon S. Matsumura, John A. Curci, Ruth McBride, William C. Blackwelder , et al. · 2016

Background differences in baseline and stimulated MMP levels influence abdominal aortic aneurysm susceptibility Open

Matthew Dale, Melissa Suh, Shijia Zhao, Trevor Meisinger, Linxia Gu , et al. · 2015

Inflammatory Cell Phenotypes in AAAs Open

Matthew Dale, Melissa K Ruhlman, B. Timothy Baxter · 2015

Abdominal aortic aneurysms (AAAs) are characterized by chronic inflammatory cell infiltration. AAA is typically an asymptomatic disease and caused ≈15 000 deaths annually in the United States. Previous studies have examined both human and …

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