Saranya Udayakumar
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View article: Hydrophosphinylation of <i>α</i> ‐Ketimino Esters to Access Unnatural Tetrasubstituted <i>α</i> ‐Phosphinyl <i>α</i> ‐Amino Acids: Cytotoxicity against Cancer Cells
Hydrophosphinylation of <i>α</i> ‐Ketimino Esters to Access Unnatural Tetrasubstituted <i>α</i> ‐Phosphinyl <i>α</i> ‐Amino Acids: Cytotoxicity against Cancer Cells Open
An efficient and concise synthesis of tetrasubstituted α ‐phosphinyl α ‐amino acids (AAs) by hydrophosphinylation of α ‐ketimino esters under catalyst‐free conditions is revealed. The strategy is simple, highly atom‐economic and environmen…
View article: Assessing the Anticancer Potential of Cerium Oxide Nanoparticles with Doxorubicin in a Polymeric Nanomatrix: Histopathological and Antiangiogenic Insights
Assessing the Anticancer Potential of Cerium Oxide Nanoparticles with Doxorubicin in a Polymeric Nanomatrix: Histopathological and Antiangiogenic Insights Open
Angiogenesis plays a pivotal role in the survival of cancer tumors, and any agent that can inhibit angiogenesis can be categorized as an efficient anticancer agent. In the present study, the synergistic anticancer effect of Cerium oxide na…
View article: Revolutionizing Cancer Vaccine: The Power of Advanced Nanotechnology
Revolutionizing Cancer Vaccine: The Power of Advanced Nanotechnology Open
Developing an effective vaccine that is safer is the main focus in the field of cancer immunotherapy. Among other therapeutic approaches, cancer nanovaccination is formulated to deliver tumor adjuvant or antigen to the antigen-presenting c…
View article: Vacuolation: A Novel Biomarker of Environmental Pollutant PFOA Induced Human Renal Proximal Tubular Cell Injury
Vacuolation: A Novel Biomarker of Environmental Pollutant PFOA Induced Human Renal Proximal Tubular Cell Injury Open
View article: Dual Mechanism of <i>Amphiroa anceps</i>: Antiangiogenic and Anticancer Effects in Skin Cancer
Dual Mechanism of <i>Amphiroa anceps</i>: Antiangiogenic and Anticancer Effects in Skin Cancer Open
Skin cancer is diagnosed usually at the last stage and the available conventional treatments are costly and have various side‐effects. It is therefore necessary to design a biocompatible alternative treatment approach. In our present study…
View article: Inhibitory Effect of Nano-Formulated Extract of Passiflora incarnata on Dalton’s Lymphoma Ascites-Bearing Swiss albino Mice
Inhibitory Effect of Nano-Formulated Extract of Passiflora incarnata on Dalton’s Lymphoma Ascites-Bearing Swiss albino Mice Open
Background/Objectives: This study explored the antitumor effect of Passiflora incarnata leaves’ nanoformulation (N-EEP) in fibroblasts, A375 cell lines, and in vivo using Dalton’s lymphoma ascites (DLA)-bearing mice. Methods: N-EEP treatme…
View article: Peony-shaped zinc oxide nanoflower synthesized via hydrothermal route exhibits promising anticancer and anti-amyloid activity
Peony-shaped zinc oxide nanoflower synthesized via hydrothermal route exhibits promising anticancer and anti-amyloid activity Open
We can conclude from the above results that the as-synthesized ZnO-NFs have a dual role as an anticancer as well as an anti-amyloid agent. In the future, animal models can be used to study the efficacy of the ZnO-NFs in cancer inhibition a…
View article: Natural serine proteases and their applications in combating amyloid formation
Natural serine proteases and their applications in combating amyloid formation Open
Background and purpose: Amyloidosis is a group of diseases including diabetes type II and neurological disorders, such as Alzheimer’s disease, Parkinson’s disease, prion disease, etc., where a common trait is observed; accumulation of misf…
View article: Enhancing Wound Healing with Nanohydrogel-Entrapped Plant Extracts and Nanosilver: An In Vitro Investigation
Enhancing Wound Healing with Nanohydrogel-Entrapped Plant Extracts and Nanosilver: An In Vitro Investigation Open
Wound healing is a complex process that can be improved through advanced biomedical approaches. Incorporating nanopolymers and plant extracts into wound dressings offers a favorable strategy for promoting tissue repair. Nanopolymers provid…
View article: Photocatalytic degradation of antibiotics and antimicrobial and anticancer activities of two-dimensional ZnO nanosheets
Photocatalytic degradation of antibiotics and antimicrobial and anticancer activities of two-dimensional ZnO nanosheets Open
View article: Unveiling the Role of Nano-Formulated Red Algae Extract in Cancer Management
Unveiling the Role of Nano-Formulated Red Algae Extract in Cancer Management Open
Cancer is one of the major causes of death, and its negative impact continues to rise globally. Chemotherapy, which is the most common therapy, has several limitations due to its tremendous side effects. Therefore, developing an alternate …
View article: Amyloidosis-history and development, emphasis on insulin and prion amyloids
Amyloidosis-history and development, emphasis on insulin and prion amyloids Open
Amyloidosis is associated with misfolding of protein (normal functional and cellular) into intractable aggregates, commonly known as amyloid fibrils. These amyloid fibrils contain thread-like structure with a high amount of β sheet content…
View article: Rough edges of reduced graphene oxide (rGO) sheets elicit anticancerous activities: An in vitro study
Rough edges of reduced graphene oxide (rGO) sheets elicit anticancerous activities: An in vitro study Open
In this study, reduced graphene oxide nanosheets (rGO) were synthesized using a chemical bottom-up technique of modified Hummer’s method. The as-synthesized graphene sheets were characterized optically by Fourier Transform Infra Red spectr…
View article: INFLUENCE OF PONGAMIA LEAF LITTER ON GROWTH AND REPRODUCTION OF EARTHWORMS, Eisenia fetida (SAVIGNY) AND Lampito mauritii (KINBERG)
INFLUENCE OF PONGAMIA LEAF LITTER ON GROWTH AND REPRODUCTION OF EARTHWORMS, Eisenia fetida (SAVIGNY) AND Lampito mauritii (KINBERG) Open
International audience
View article: Evaluating the performance of phosphatic fertilizers on plant nutrients (N, P and K) concentration and uptake by the rice crop
Evaluating the performance of phosphatic fertilizers on plant nutrients (N, P and K) concentration and uptake by the rice crop Open
A field experiment was taken up in the farmers’ field at Irumbadi village of Vadipatti block of Madurai district during rabi 2013 with rice (var. ADT 39) as test crop to evaluate the influence of P sources and forms (SSP and complex P with…
View article: Soil test based integrated plant nutrition system for pearl millet on an Inceptisol
Soil test based integrated plant nutrition system for pearl millet on an Inceptisol Open
View article: Evaluating the effect of phosphatic fertilizers on soil and plant P availability and maximising rice crop yield
Evaluating the effect of phosphatic fertilizers on soil and plant P availability and maximising rice crop yield Open