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View article: Sindbis Virus–Host Interactions in Human Neuroblastoma Cells: Implications for Viral Pathogenesis and Replication
Sindbis Virus–Host Interactions in Human Neuroblastoma Cells: Implications for Viral Pathogenesis and Replication Open
Sindbis virus (SINV) is a mosquito-borne alphavirus capable of causing neurological and immunological symptoms in humans, yet its effects on neural/immune systems remain insufficiently characterized. This study aimed to examine SINV replic…
View article: Safety and efficacy of maxillomandibular fixation techniques: a network meta-analysis
Safety and efficacy of maxillomandibular fixation techniques: a network meta-analysis Open
Jaw fractures are prevalent facial injuries. Choosing the optimal intermaxillary/maxillomandibular fixation(IMF/MMF) technique is crucial for a successful conservative and surgical treatment, to achieve perfect occlusion.This network meta-…
View article: Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products
Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products Open
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and pay…
View article: Intraoperative Surgical Navigation Is as Effective as Conventional Surgery for Zygomaticomaxillary Complex Fracture Reduction
Intraoperative Surgical Navigation Is as Effective as Conventional Surgery for Zygomaticomaxillary Complex Fracture Reduction Open
Background/Objectives: Zygomaticomaxillary complex (ZMC) fractures are the second most common of all facial bone fractures, and conventional treatment represents a challenge even for experienced surgeons. The aim of this systematic review …
View article: TWIN-MIX INJECTION REDUCES POSTOPERATIVE COMPLICATIONS AFTER LOWER THIRD MOLAR REMOVAL—A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS
TWIN-MIX INJECTION REDUCES POSTOPERATIVE COMPLICATIONS AFTER LOWER THIRD MOLAR REMOVAL—A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS Open
In conclusion, the use of twin-mix is highly beneficial for pain relief, facial swelling and trismus following mandibular third molar surgical removal.
View article: Regeneration of Chronic Alveolar Vertical Defects Using a Micro Dosage of rhBMP‐2. An Experimental In Vivo Study
Regeneration of Chronic Alveolar Vertical Defects Using a Micro Dosage of rhBMP‐2. An Experimental In Vivo Study Open
OBJECTIVE: The objective of this study is to compare the effect of the location of recombinant human bone morphogenetic protein 2 (rhBMP-2) from the native bone and the periosteum for vertical alveolar bone augmentation. MATERIALS AND METH…
View article: Non-Invasive Strategies for Remineralization and Hypersensitivity Management in Molar–Incisor Hypomineralization—A Systematic Review and Meta-Analysis
Non-Invasive Strategies for Remineralization and Hypersensitivity Management in Molar–Incisor Hypomineralization—A Systematic Review and Meta-Analysis Open
Background: Molar–incisor hypomineralization (MIH) is an enamel defect affecting molars and incisors, often leading to hypersensitivity, enamel breakdown, and increased caries risk. Non-invasive treatments, such as casein phosphopeptide–am…
View article: Regeneration of Chronic Alveolar Vertical Defects Using a Micro Dosage of rhBMP‐2. An Experimental In Vivo Study
Regeneration of Chronic Alveolar Vertical Defects Using a Micro Dosage of rhBMP‐2. An Experimental In Vivo Study Open
Objective The objective of this study is to compare the effect of the location of recombinant human bone morphogenetic protein 2 (rhBMP‐2) from the native bone and the periosteum for vertical alveolar bone augmentation. Materials and Metho…
View article: Mapping patient pathways for NCDs from a policy perspective: a novel multinational initiative
Mapping patient pathways for NCDs from a policy perspective: a novel multinational initiative Open
Background Chronic diseases like CVD and DM pose global health challenges. Understanding patient pathways is vital for effective disease management and reducing morbidity and mortality. However, until now, comprehensive multinational mappi…
View article: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor
Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor Open
Tirzepatide, a glucose-dependent insulinotropic polypeptide/glucagon-like peptide 1 receptor (GIPR/GLP-1R) agonist, has, in clinical trials, demonstrated greater reductions in glucose, body weight, and triglyceride levels compared with sel…
View article: Prediabetes and poorly controlled type-2 diabetes as risk indicators for peri-implant diseases:A systematic review and meta-analysis
Prediabetes and poorly controlled type-2 diabetes as risk indicators for peri-implant diseases:A systematic review and meta-analysis Open
Clinicians should measure blood HbA1c levels when planning implant-supported restorations, thus patients with undiagnosed or poorly controlled type-2 diabetes can be identified, that allows for glycemic level adjustment prior to dental imp…
View article: Hyperpure chlorine dioxide versus chlorhexidine in intra-oral halitosis (ODOR trial) – protocol of a double-blinded, double-arm, parallel non-inferiority pilot randomized controlled trial
Hyperpure chlorine dioxide versus chlorhexidine in intra-oral halitosis (ODOR trial) – protocol of a double-blinded, double-arm, parallel non-inferiority pilot randomized controlled trial Open
Introduction Intra-oral halitosis (IOH) is the most common type of bad breath; its consequences impair quality of life. However, evidence-based treatment protocols and guidelines are lacking. Our aim is to investigate the effectiveness of …
View article: The Effect of Nicotine-Containing Products on Peri-Implant Tissues: A Systematic Review and Network Meta-Analysis
The Effect of Nicotine-Containing Products on Peri-Implant Tissues: A Systematic Review and Network Meta-Analysis Open
Introduction Smokers have a higher chance of developing peri-implant diseases and are therefore considered an at-risk population. Our aim was to compare peri-implant characteristics in users of electronic cigarettes (EC), waterpipes (WP), …
View article: Aromatase Inhibitors and Plasma Lipid Changes in Postmenopausal Women with Breast Cancer: A Systematic Review and Meta-Analysis
Aromatase Inhibitors and Plasma Lipid Changes in Postmenopausal Women with Breast Cancer: A Systematic Review and Meta-Analysis Open
Background: Women are typically diagnosed with estrogen receptor-positive breast cancer around the postmenopausal period when declining estrogen levels initiate changes in lipid profiles. Aromatase inhibitors (AI) are used to prevent the p…
View article: Channel-reach morphometric analysis on a headwater stream in a low-mountainous region: a case study from Mecsek Hills
Channel-reach morphometric analysis on a headwater stream in a low-mountainous region: a case study from Mecsek Hills Open
Small catchments in mountainous regions affect downstream rivers as a primary source of sediment supply and also generate flash swasfloods, especially during extreme events. These floods have significantly shaped the catchments of small st…
View article: Accuracy of conventional versus additive cast-fabrication in implant prosthodontics: A systematic review and meta-analysis of <i>in vitro</i> studies
Accuracy of conventional versus additive cast-fabrication in implant prosthodontics: A systematic review and meta-analysis of <i>in vitro</i> studies Open
Additive cast-fabrication is as accurate as the conventional method for the position of implant analogs.
View article: Comparative analysis of surgical and prosthetic rehabilitation in maxillectomy: A systematic review and meta-analysis on quality-of-life scores and objective speech and masticatory measurements
Comparative analysis of surgical and prosthetic rehabilitation in maxillectomy: A systematic review and meta-analysis on quality-of-life scores and objective speech and masticatory measurements Open
The growing number of maxillectomy patients demands firm evidence on which rehabilitation to choose and when it should be done. The result suggests that obturator devices and surgical reconstruction have similar effects on quality of life …
View article: Advancing accuracy in guided implant placement: A comprehensive meta-analysis
Advancing accuracy in guided implant placement: A comprehensive meta-analysis Open
To our knowledge, this is the first meta-analysis to evaluate the accuracy of robotic CAIS and investigate the accuracy of various CAIS modalities.
View article: Effect of Chitosan on the Number of Streptococcus mutans in Saliva: A Meta-Analysis and Systematic Review
Effect of Chitosan on the Number of Streptococcus mutans in Saliva: A Meta-Analysis and Systematic Review Open
We conducted a meta-analysis and systematic review to investigate the efficacy of chitosan-containing chewing gums, and to test their inhibitory effects on Streptococcus mutans. The systematic search was performed in three databases (Cochr…
View article: Less marginal bone loss around bone‐level implants restored with long abutments: A systematic review and meta‐analysis
Less marginal bone loss around bone‐level implants restored with long abutments: A systematic review and meta‐analysis Open
The aim of this study was to investigate the biological outcomes of bone‐level implants restored with long vs. short abutments, with regard to the ‘one abutment at one time’ protocol. The systematic search was performed in five databases: …
View article: Current status of optical scanning in facial prosthetics: A systematic review and meta-analysis
Current status of optical scanning in facial prosthetics: A systematic review and meta-analysis Open
Purpose To assess the accuracy of scanning technologies for constructing facial prostheses on human faces.Study selection Our systematic search was performed on five databases. Studies reporting on human volunteers (P) whose faces were sca…
View article: Clear guidance to select the most accurate technologies for 3D printing dental models – A network meta-analysis✰
Clear guidance to select the most accurate technologies for 3D printing dental models – A network meta-analysis✰ Open
The findings of the NMA suggest that SLA, DLP, and PolyJet technologies are sufficiently accurate for full-arch dental model production for prosthodontic purposes. In contrast, FDM/FFF, CLIP, and LCD technologies are less suitable for manu…
View article: Characterization and mapping of MIS‐2 thermal contraction crack polygons in Western Transdanubia, Hungary
Characterization and mapping of MIS‐2 thermal contraction crack polygons in Western Transdanubia, Hungary Open
The Pannonian Basin was located in the southernmost, disputed limit of permafrost during the Last Glacial Maximum (LGM). In the western part of the basin, over an area of 1,200 km 2 , more than 150 sites with polygonal patterned ground wer…
View article: The use of autogenous tooth bone graft is an efficient method of alveolar ridge preservation – meta-analysis and systematic review
The use of autogenous tooth bone graft is an efficient method of alveolar ridge preservation – meta-analysis and systematic review Open
Background Ridge resorption following tooth extraction may be reduced by alveolar ridge preservation (ARP). Previous randomized clinical trials and systematic reviews have suggested that autogenous tooth bone graft (ATB) can be an effectiv…
View article: ORGANOLEPTIC AND HALITOMETRIC ASSESSMENTS DO NOT CORRELATE WELL IN INTRA-ORAL HALITOSIS: A SYSTEMATIC REVIEW AND META-ANALYSIS
ORGANOLEPTIC AND HALITOMETRIC ASSESSMENTS DO NOT CORRELATE WELL IN INTRA-ORAL HALITOSIS: A SYSTEMATIC REVIEW AND META-ANALYSIS Open
None of the most commonly used halitometers proved to be significantly superior to the others. Halimeter and OralChroma measurements did not correlate well with the organoleptic level of oral halitosis in adults. Therefore, better halitome…
View article: The Wisdom in Teeth: Neuronal Differentiation of Dental Pulp Cells
The Wisdom in Teeth: Neuronal Differentiation of Dental Pulp Cells Open
Mesenchymal stem/stromal cells (MSCs) are found in almost all postnatal organs. Under appropriate environmental cues, multipotency enables MSCs to serve as progenitors for several lineage-specific, differentiated cell types. In vitro expan…
View article: Target-Based Guidance Method for Trajectories with Multiple Flybys
Target-Based Guidance Method for Trajectories with Multiple Flybys Open
IIN A real-life scenario, a spacecraft will not follow the prescribed nominal path. As a matter of fact, uncertainty in the dynamic model (e.g., gravitational parameters or radiation pressure noisy profiles) can lead to relevant drifts dur…