Bernard W. Downs
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Beneficial effects of PerformLyte<sup>TM</sup>, a prodosomed phytonutrient-enriched electrolyte formulation, in enhancing neuro-muscular synergy, immune competence, cellular aerobic glycolysis and sports performance Open
An optimised sports nutrition formulation achieving the correct blend of electrolytes with antioxidants and vitamins is integral towards meeting the demanding performance in professional sports arena. In this work, we describe a pilot stud…
Inflammatory responses and obesity: Nutrition as an epigenetic modulator Open
The onset of inflammation takes place in a human body due to an injury or infection during which the tissue becomes inflamed/reddened, swollen, hot, and painful. Basically, it is a collection of host defenses that occurs during an injury a…
Effective body recomposition vs. misconceptions of the traditional weight loss strategies: TRCAP21 - a novel technological breakthrough in body recomposition Open
Background: The prevalence of obesity has increased an astounding 30.5% to 42.2% over the last two decades despite numerous weight loss products and programs, thus qualifying it as an epidemic. Fat is the lightest of macromolecules, the hi…
A technological breakthrough in developing a state-of-the-art nutraceutical sports nutrition formulation to enhance vitality, mental acuity, vigilance, energy, and stamina Open
The researchers demonstrate the development of a novel Prodosome technology-derived PL425 PEC phytonutrient-enriched electrolyte formulation and its significant contribution in fluid homeostasis as well as enhanced neuromuscular function, …
Hypothesizing That Pediatric Autoimmune Neuropsychiatric Associated Streptococcal (PANDAS) Causes Rapid Onset of Reward Deficiency Syndrome (RDS) Behaviors and May Require Induction of “Dopamine Homeostasis” Open
Pediatric autoimmune neuropsychiatric disorders associated with group A streptococcal infections (PANDAS) is a concept that is used to characterize a subset of children with neuropsychiatric symptoms, tic disorders, or obsessive-compulsive…
Assessment of a Novel Bioflavonoids and Phytonutrient Formulation in Enhancing Cellular Aerobic Glycolysis, Immunity, Sports Performance, and Mitigating Inflammation Open
Metabolic competence in conjunction with well-balanced nutritional support is extremely important for normal biochemical and physiological functions, as well as for enhanced athletic performance. Research-affirmed nutraceuticals enriched i…
Design of a Novel Bioflavonoid and Phytonutrient Enriched Formulation in Boosting Immune Competence and Sports Performance: A product Development Investigation Open
An increase in anaerobic (oxygen-deprived) pathogenesis significantly increases the generation of reactive oxygen species (ROS) inflicting damage on cell membranes and intracellular constituents. Generation of ROS and concomitant inflammat…
Functional foods beyond nutrition: therapeutic interventions to combat COVID-19 and other viral diseases Open
SARS-COV2 has emerged as the second biggest threat to humanity of all times, after the Spanish Flu massacre. Due to its brisk rate of mutation, especially that of the host receptor docking Spike protein, a safe immunization is still questi…
Endorphinergic Enhancement Attenuation of Post-traumatic Stress Disorder (PTSD) via Activation of Neuro-immunological Function in the Face of a Viral Pandemic Open
Introduction: Polymorphic gene variants, particularly the genetic determinants of low dopamine function (hypodopaminergia), are known to associate with Substance Use Disorder (SUD) and a predisposition to PTSD. Addiction research and molec…
A novel strategy for processing, production and quality control of an iron-free nutraceutical supplement that rapidly restores iron-dependent hemoglobin in red blood cells Open
We hypothesize that Iron-Deficiency Anemia (IDA) has been misconceptualized. In the body, low blood iron is not caused by a deficiency. The primary cause of low iron, appearing to be IDA, is the expenditure of alkalinizing histidine, from …
Induction of homeostatic biological parameters in reward deficiency as a function of an iron-free multi-nutrient complex: Promoting hemoglobinization, aerobic metabolism, viral immuno-competence, and neuroinflammatory regulation Open
The Clinical investigation in a total of 38 subjects was conducted under an Institutional Review Board (IRB) from the Path Foundation in New York, NY (#13-009 April 25, 2013). The two case studies were done at Lancaster General Hospital, L…
VMP35 MNC, a novel iron-free supplement, enhances cytoprotection against anemia in human subjects: a novel hypothesis Open
Overall, the non-iron containing VMP35 can induce improvements in blood properties and potential benefits for subjects even with compromised digestive systems. No adverse events were reported. Further research studies are in progress to ex…
View article: Safety and Efficacy of N-SORB<sup>®</sup>, a Proprietary KD120 MEC Metabolically Activated Enzyme Formulation: A Randomized, Double-Blind, Placebo-Controlled Study
Safety and Efficacy of N-SORB<sup>®</sup>, a Proprietary KD120 MEC Metabolically Activated Enzyme Formulation: A Randomized, Double-Blind, Placebo-Controlled Study Open
Background: Enzymes are crucial for all aspects of metabolic function. Digestive enzymes from natural sources have been credited with beneficial effects in the digestion and absorption of food. N-SORB is a novel KD120 multienzyme complex (…
“Dopamine homeostasis” requires balanced polypharmacy: Issue with destructive, powerful dopamine agents to combat America’s drug epidemic Open
The well-researched pro-dopamine regulator KB220 and variants result in increased functional connectivity in both animal and human brains, and prolonged neuroplasticity (brain cell repair) having been observed in rodents. Moreover, in addi…