Bahador Mirrahimi
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View article: Comparison of Sequential versus Concurrent Albumin and Furosemide in Pediatric Nephrotic Syndrome Patients: A Blinded Randomized Controlled Clinical Trial
Comparison of Sequential versus Concurrent Albumin and Furosemide in Pediatric Nephrotic Syndrome Patients: A Blinded Randomized Controlled Clinical Trial Open
OBJECTIVE Comparing the effectiveness of sequential and concurrent administration of albumin and furosemide in reducing edema in children with nephrotic syndrome. METHOD A double blinded randomized controlled clinical trial was conducted i…
View article: Efficacy of Inhaled Colistin in Critically Ill Children with Ventilator-Associated Pneumonia Resistant to Multiple Drugs
Efficacy of Inhaled Colistin in Critically Ill Children with Ventilator-Associated Pneumonia Resistant to Multiple Drugs Open
Background: Ventilator-associated pneumonia (VAP) is the leading cause of death related to mechanical ventilation and the most common nosocomial infection in the intensive care unit (ICU). Objectives: This study aimed to investigate the ef…
View article: Comparison of the Areas Under the Curve of Vancomycin Continuous vs. Intermittent Infusion in Critically Ill Pediatrics: A Randomized Clinical Trial
Comparison of the Areas Under the Curve of Vancomycin Continuous vs. Intermittent Infusion in Critically Ill Pediatrics: A Randomized Clinical Trial Open
Background: Providing data on the superior efficacy of vancomycin administered based on the area under the curve over 24 hours to the minimum inhibitory concentration of vancomycin (AUC24/MIC) is crucial. However, data on dosing and monito…
View article: The Drug Effectiveness and Side Effects of Remdesivir in Neonatal COVID-19: A Case Series Study
The Drug Effectiveness and Side Effects of Remdesivir in Neonatal COVID-19: A Case Series Study Open
: Due to the novelty of COVID-19, no definite treatment has yet been found for this infectious disease, especially in neonates and early infants. Although most of the neonates affected by this virus have a mild or silent course of the dise…
View article: Appropriateness of Antibiotic Prescribing in the Emergency Department of Mofid Children's Hospital: A Retrospective Cross-Sectional Study
Appropriateness of Antibiotic Prescribing in the Emergency Department of Mofid Children's Hospital: A Retrospective Cross-Sectional Study Open
Background: Antibiotics should be used to treat bacterial infections, while prescribing antibiotics for viral infections is ineffective. Sometimes, physicians do not diagnose diseases correctly and misdiagnose viral infections as bacterial…
View article: Evaluating the efficacy of inhaled amikacin as an adjunct to intravenous combination therapy (ceftazidime and amikacin) in pediatric cystic fibrosis pulmonary exacerbation
Evaluating the efficacy of inhaled amikacin as an adjunct to intravenous combination therapy (ceftazidime and amikacin) in pediatric cystic fibrosis pulmonary exacerbation Open
Background: Pseudomonas aeruginosa is the most common microorganism found in the sputum culture of Cystic fibrosis (CF) patients causing the pulmonary destruction. Aminoglycosides have a low diffuse rate from lipid membranes, and respirato…
View article: Evaluating the Effect of Eicosapentaenoic Acid in Children With Atopic Dermatitis: A Randomized Triple-Blind Clinical Trial
Evaluating the Effect of Eicosapentaenoic Acid in Children With Atopic Dermatitis: A Randomized Triple-Blind Clinical Trial Open
OBJECTIVE To evaluate the effects of dietary eicosapentaenoic acid (EPA) in children with atopic dermatitis. METHODS Forty-eight children with atopic dermatitis were randomly allocated to receive either 250 mg twice daily EPA (n = 24) or p…
View article: Questioning Diagnostic Value of Serum Matrix Metalloproteinase 7 for Biliary Atresia
Questioning Diagnostic Value of Serum Matrix Metalloproteinase 7 for Biliary Atresia Open
View article: Probiotic prophylaxis to prevent ventilator-associated pneumonia in children on mechanical ventilation: A randomized double-blind clinical trial
Probiotic prophylaxis to prevent ventilator-associated pneumonia in children on mechanical ventilation: A randomized double-blind clinical trial Open
Purpose Ventilator-Associated Pneumonia (VAP) is one of the most common nosocomial infections in the Pediatric Intensive Care Unit (PICU). Using new strategies to prevent nosocomial infections is crucial to avoid antibiotic resistance. One…
View article: Prevalence and Severity of Drug Interactions in a Referral Pediatric Hospital: An Observational, Retrospective Study
Prevalence and Severity of Drug Interactions in a Referral Pediatric Hospital: An Observational, Retrospective Study Open
Background: Hospitalized infants and children are usually treated with many medications in the hospital. Concurrent use of multiple drugs, known as polypharmacy, is inevitable in critically ill patients. This study aims to investigate the …
View article: Serum matrix metalloproteinase-7 levels in infants with cholestasis and biliary atresia
Serum matrix metalloproteinase-7 levels in infants with cholestasis and biliary atresia Open
Background The aim of this study was to evaluate the serum level of matrix metalloproteinase 7 (MMP7) in infants with cholestasis and the diagnostic values of this biomarker to differentiate biliary atresia (BA) from other causes of choles…
View article: Nutrition Section Position Statement and Clinical Practice Recommendations for Children Admitted to Intensive Care Unit
Nutrition Section Position Statement and Clinical Practice Recommendations for Children Admitted to Intensive Care Unit Open
Context: Children admitted to the intensive care unit are at risk of malnutrition, mainly due to chronic diseases they are suffering from. These patients require a different nutritional diet regimen from those in a normal or stable disease…
View article: A Single-Centered Cohort Study on Favipiravir Safety and Efficacy in Pediatric Patients with COVID-19
A Single-Centered Cohort Study on Favipiravir Safety and Efficacy in Pediatric Patients with COVID-19 Open
Background: Coronavirus disease 2019 (COVID-19) affects the pediatric population. Objectives: Due to limited data, this study aimed to evaluate the safety and efficacy of favipiravir in the hospitalized pediatric population diagnosed with …
View article: Octreotide Efficacy and Safety in Pediatric Non-variceal Upper Gastrointestinal Bleeding: A Randomized Placebo-Controlled Clinical Trial
Octreotide Efficacy and Safety in Pediatric Non-variceal Upper Gastrointestinal Bleeding: A Randomized Placebo-Controlled Clinical Trial Open
Background: Octreotide has been used to control bleeding episodes with variceal origin in the pediatric population. To date, there is no clear evidence of octreotide use for non-variceal bleeding in clinical trials. Objectives: We aimed to…
View article: Intravesical alprostadil as a promising agent in BK virus-associated hemorrhagic cystitis: A report of a refractory case
Intravesical alprostadil as a promising agent in BK virus-associated hemorrhagic cystitis: A report of a refractory case Open
Allogeneic stem cell transplant recipients are at risk of BK virus-associated hemorrhagic cystitis. This condition causes a significant morbidity and worsens clinical outcomes. The standard cares for BK virus-associated hemorrhagic cystiti…
View article: Implementing the Protocol of Perioperative Narrow-spectrum Antibiotic Prophylaxis in the Surgical Wards of Mofid Children’s Hospital in 2019 - 2020, A Comparative Study
Implementing the Protocol of Perioperative Narrow-spectrum Antibiotic Prophylaxis in the Surgical Wards of Mofid Children’s Hospital in 2019 - 2020, A Comparative Study Open
Background: Surgical procedures may be complicated by post-surgical infections. This study investigates the role of administering perioperative narrow-spectrum antibiotic prophylaxis in preventing post-surgical infections as compared to ro…
View article: Impact of Intravenous Pantoprazole versus Oral Pantoprazole on Gastric pH in Pediatric Intensive Care Unit: A Randomized Trial
Impact of Intravenous Pantoprazole versus Oral Pantoprazole on Gastric pH in Pediatric Intensive Care Unit: A Randomized Trial Open
Critically ill patients are at risk for development of stress-related mucosal damage (SRMD). Proton Pump Inhibiros (PPIs) like pantoprazole are extensively used to prevent SRMD in ICU settings. It is not known with certainty that either or…
View article: An Algorithmic Approach to Management of COVID-19 Associated Multisystem Inflammatory Syndrome in Children
An Algorithmic Approach to Management of COVID-19 Associated Multisystem Inflammatory Syndrome in Children Open
View article: Octreotide Safety and Efficacy in Pediatric Non-variceal Upper Gastrointestinal Bleeding, A Randomized Controlled Trial
Octreotide Safety and Efficacy in Pediatric Non-variceal Upper Gastrointestinal Bleeding, A Randomized Controlled Trial Open
Background: Octreotide as somatostatin analogue decrease the production of gastrointestinal (GI) peptides. Its consumption in pediatric population has been limited to control of bleeding episodes with variceal origin. In this randomized co…
View article: Posaconazole-Induced Acute Pancreatitis: A Rare Side Effect in a Child with Chronic Granulomatous Disease
Posaconazole-Induced Acute Pancreatitis: A Rare Side Effect in a Child with Chronic Granulomatous Disease Open
Introduction: Pancreatitis is an inflammatory disease of the pancreas. Drug-induced pancreatitis is an important cause of pancreatitis. There are two pathological types of acute pancreatitis, including pancreatic edema with a mild course a…
View article: An Algorithmic Approach to Diagnosis and Treatment of Coronavirus Disease 2019 (COVID-19) in Children: Iranian Expert’s Consensus Statement
An Algorithmic Approach to Diagnosis and Treatment of Coronavirus Disease 2019 (COVID-19) in Children: Iranian Expert’s Consensus Statement Open
: After the outbreak of 2019 novel corona virus infection in China, we have the outbreak of disease in Iran and until March 05, 2020 have been reported a total number of confirmed cases more than 3500 and approximately 3.3% deaths. The cor…
View article: A Randomized Clinical Trial Evaluating the Efficacy of Colistin Loading Dose in Critically Ill Children
A Randomized Clinical Trial Evaluating the Efficacy of Colistin Loading Dose in Critically Ill Children Open
Objective: Pharmacokinetic and clinical studies recommend applying loading dose of colistin for the treatment of severe infections in the critically ill adults. Pharmacokinetic studies of colistin in children also highlight the need for a …
View article: Clinical use of statins in hematopoietic stem cell transplantation: Old drugs and new horizons.
Clinical use of statins in hematopoietic stem cell transplantation: Old drugs and new horizons. Open
Hydroxymethylglutaryl Co-enzyme A reductase inhibitors, also known as statins, are a class of anti-hyperlipidemic agents. These drugs have been employed vastly to reduce the morbidity and mortality of cardiovascular disorders. Soon after t…