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View article: Identifying robust neural signatures of acupuncture modulation in healthy brains: a multimodal meta-analysis mapping core network
Identifying robust neural signatures of acupuncture modulation in healthy brains: a multimodal meta-analysis mapping core network Open
Acupuncture, a cornerstone of Chinese integrative medicine, demonstrates clinical efficacy for pain- and inflammation-related conditions through extensive clinical practices. Using multimodal neuroimaging techniques (fMRI and PET), numerou…
View article: Electroacupuncture alleviates Parkinson’s disease by inhibiting the NLRP3 inflammasome pathway
Electroacupuncture alleviates Parkinson’s disease by inhibiting the NLRP3 inflammasome pathway Open
EA mitigates PD symptoms and exerts neuroprotective effects by inhibiting NLRP3 inflammasome-mediated neuroinflammation.
View article: The rapid antidepressant effect of acupuncture on two animal models of depression by increasing the expression of synaptic proteins in the prefrontal cortex
The rapid antidepressant effect of acupuncture on two animal models of depression by increasing the expression of synaptic proteins in the prefrontal cortex Open
Objective: To investigate the effect of acupuncture onset time and synaptic structure in two different models of depression. Methods: A total of 150 healthy male adult SPF C57BL/6J mice were divided into five time-point groups: 1 h, 3 h, 6…
View article: β-Asarone Promotes Autophagy by Inhibiting the PI3K/Akt/mTOR Pathway in a Rat Model of Depression in Parkinson’s Disease
β-Asarone Promotes Autophagy by Inhibiting the PI3K/Akt/mTOR Pathway in a Rat Model of Depression in Parkinson’s Disease Open
Depression in Parkinson’s disease (DPD) is a major non-motor symptom of Parkinson’s disease (PD), and is accompanied by monoamine neurotransmitter degradation in DPD rats. Autophagy is neuroprotective because it helps degrade abnormal depo…
View article: Efficacy of the Integrative Acupuncture and Moxibustion Treatment in Patients With Major Depressive Disorder: The Study Protocol for a Multicenter, Single-Blinded, Randomized Trial in China
Efficacy of the Integrative Acupuncture and Moxibustion Treatment in Patients With Major Depressive Disorder: The Study Protocol for a Multicenter, Single-Blinded, Randomized Trial in China Open
Introduction Antidepressants are the front-line treatments for major depressive disorder (MDD), but remain unsatisfactory in outcome. An increasing number of patients are interested in acupuncture and moxibustion treatment as complementary…
View article: Total ginsenoside and Acorus tatarinowii volatile oil co-administration reverses learning memory deficits, reduces Aβ42 and AChE levels, and downregulates the PI3K/Akt/mTOR/Beclin-1 autophagic pathway in APP/PS1 double transgenic mice
Total ginsenoside and Acorus tatarinowii volatile oil co-administration reverses learning memory deficits, reduces Aβ42 and AChE levels, and downregulates the PI3K/Akt/mTOR/Beclin-1 autophagic pathway in APP/PS1 double transgenic mice Open
Ethnopharmacological Relevance: The combined application of ginseng and Shichangpu comes from the nootropic prescription—Dingzhi Xiaowan. One of the main effective components of ginseng is saponins. Studies have reported that its total sap…
View article: The Role of Acupuncture in Hormonal Shock-Induced Cognitive-Related Symptoms in Perimenopausal Depression: A Randomized Clinical Controlled Trial
The Role of Acupuncture in Hormonal Shock-Induced Cognitive-Related Symptoms in Perimenopausal Depression: A Randomized Clinical Controlled Trial Open
Introduction: Perimenopausal depression is predominantly caused by hormone shock, but the underlying physical and psychological factors are still unclear. Objectives: To explore the constituent components of perimenopausal depression by dy…
View article: Effect of Inhibited T lymphocyte Function on Depressive Symptoms in Breast Cancer Patients with Depression
Effect of Inhibited T lymphocyte Function on Depressive Symptoms in Breast Cancer Patients with Depression Open
Background : Depression has a high incidence among patients with breast cancer, but the relationship between depression and cancer-related physiological changes is not clear. Objectives : To explore the effect of T lymphocytes on breast ca…
View article: Implementation and Evaluation of the Integrated Acupuncture and Moxibustion Treatment (Acupuncture, Moxibustion and Auricular Acupuncture) for Major Depressive Disorder: A Trial Protocol for a Randomized Clinical Trial
Implementation and Evaluation of the Integrated Acupuncture and Moxibustion Treatment (Acupuncture, Moxibustion and Auricular Acupuncture) for Major Depressive Disorder: A Trial Protocol for a Randomized Clinical Trial Open
Background: Because of inadequate psychotherapy resources, antidepressants are the front-line option for Major depressive disorder, but with dissatisfied curative effect. Many patients have an interest in acupuncture and moxibustion treatm…
View article: Intradermal Thumbtack Needle Alleviates Depressive Symptoms and Resets Executive Control System Function in Young Patients With Subthreshold Depression: A Study Protocol of a Randomized, Controlled, and Single-Blind Trial {1}
Intradermal Thumbtack Needle Alleviates Depressive Symptoms and Resets Executive Control System Function in Young Patients With Subthreshold Depression: A Study Protocol of a Randomized, Controlled, and Single-Blind Trial {1} Open
Background: Subthreshold depression is the prodromal stage of a depressive episode, which is characterized by depressive symptoms but fails to meet the diagnostic criteria for depression. At present, there is no recognized therapy for subt…
View article: Effectiveness and safety of moxibustion for Parkinson disease
Effectiveness and safety of moxibustion for Parkinson disease Open
Background: Parkinson disease (PD) is a common neurodegenerative disease among middle-aged and elderly people. Clinically, it is a movement disorder characterized mainly by static tremors, kinesia, myotonia, and postural balance disorder. …
View article: Acupuncture for comorbid mild-moderate depression and chronic musculoskeletal pain: study protocol for a randomized controlled trial
Acupuncture for comorbid mild-moderate depression and chronic musculoskeletal pain: study protocol for a randomized controlled trial Open
Background Depression and chronic musculoskeletal pain (CMSP) are the leading causes of years lived with disabling diseases worldwide. Moreover, they often commonly coexist, which makes diagnosis and treatment difficult. A safe and effecti…
View article: Effectiveness and safety of Moxibustion for Parkinson's disease：a protocol for systematic review and meta-analysis
Effectiveness and safety of Moxibustion for Parkinson's disease：a protocol for systematic review and meta-analysis Open
Review / Objective: To evaluate the effectiveness and safety of Moxibustion in the treatment of Parkinson's disease.Condition being studied: Parkinson's disease (PD) is the second most common progressive neurodegenerative disorder influenc…
View article: Acupuncture for Comorbid Mild-Moderate Depression and Chronic Musculoskeletal Pain: Study Protocol for A Randomized Controlled Trial
Acupuncture for Comorbid Mild-Moderate Depression and Chronic Musculoskeletal Pain: Study Protocol for A Randomized Controlled Trial Open
Background: Depression and Chronic musculoskeletal pain (CMSP) are the leading causes of global years lived with disability diseases. Moreover, they often commonly coexist, which made a great difficult to diagnosis and treatment. A safe an…
View article: Acupuncture plus rehabilitation for post-stroke depression
Acupuncture plus rehabilitation for post-stroke depression Open
Background: Post-stroke depression (PSD) is a common stroke complication that is characterized by hopelessness, anxiety, disordered sleep, and lowered responsiveness. Rehabilitation and acupuncture treatments are often combined to treat PS…
View article: Acupuncture plus Rehabilitation for Unilateral Neglect after Stroke: A Systematic Review and Meta‐Analysis
Acupuncture plus Rehabilitation for Unilateral Neglect after Stroke: A Systematic Review and Meta‐Analysis Open
Objectives . To systematically assess the efficacy of acupuncture combined with rehabilitation on unilateral neglect after stroke. Methods . The Cochrane Library, PubMed, Excerpt Medical Database (EMBASE), China National Knowledge Infrastr…
View article: Anti-diabetic agents for prevention of type 2 diabetes mellitus in people with pre-diabetes: a systematic review and network meta-analysis protocol
Anti-diabetic agents for prevention of type 2 diabetes mellitus in people with pre-diabetes: a systematic review and network meta-analysis protocol Open
Introduction Type 2 diabetes mellitus (T2DM) is a substantial health problem worldwide. Pre-diabetic state is associated with increased risk for the development of diabetes. There are various pharmacological therapies with glucose-lowering…