Bin Zhao
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View article: Comparison of SEEKflex/videolaryngoscopy and fibreoptic bronchoscope for awake tracheal intubation: a randomized clinical trial
Comparison of SEEKflex/videolaryngoscopy and fibreoptic bronchoscope for awake tracheal intubation: a randomized clinical trial Open
View article: Comparison of ioversol and iodixanol related adverse drug reactions in cerebrovascular interventional procedures
Comparison of ioversol and iodixanol related adverse drug reactions in cerebrovascular interventional procedures Open
The incidence of iodinated contrast media (ICM)-related adverse drug reactions (ADRs) varies significantly by procedure type. Compared other procedure types, cerebrovascular interventional procedures substantially increase the incidence of…
View article: Boosting Hydroxyl Radical Generation with Nitrogen Vacancy–Modified Carbon Nitride for Triggering Dual Damage of Cancer Nucleus DNA–Mitochondria against Hypoxic Tumors
Boosting Hydroxyl Radical Generation with Nitrogen Vacancy–Modified Carbon Nitride for Triggering Dual Damage of Cancer Nucleus DNA–Mitochondria against Hypoxic Tumors Open
Collectively, the high •OH-generation efficiency, strong anticancer activity, and overall safety of the O2-independent nanoparticle opens up new avenues for in-depth study on carbon nitride-based cancer PDT strategies. This work…
View article: Case Report: Surgical androgen deprivation therapy for prostate cancer in a patient with concurrent scrotal paget’s disease
Case Report: Surgical androgen deprivation therapy for prostate cancer in a patient with concurrent scrotal paget’s disease Open
Introduction Prostate cancer (PCa) and Scrotal Paget’s disease (SPD) are two distinct malignancies, and reports of their concurrent occurrence are very limited. The aim of this case was to discuss the individualized treatment strategy for …
View article: Context-Aware Sentiment Forecasting via LLM-based Multi-Perspective Role-Playing Agents
Context-Aware Sentiment Forecasting via LLM-based Multi-Perspective Role-Playing Agents Open
View article: Deep Learning-Based Pathomics Signature Predicts Prognosis and Treatment Response in Gastric Cancer: A Multicenter Retrospective Study
Deep Learning-Based Pathomics Signature Predicts Prognosis and Treatment Response in Gastric Cancer: A Multicenter Retrospective Study Open
View article: Safe Easy Endotracheal Kit-flexible-guided endotracheal intubation reduces stress response under general anesthesia: a randomized controlled trial
Safe Easy Endotracheal Kit-flexible-guided endotracheal intubation reduces stress response under general anesthesia: a randomized controlled trial Open
SEEKflex-guided intubation, compared to the traditional tube core method, resulted in more stable hemodynamic responses and a higher first intubation success rate.
View article: EmbodiedCity: A Benchmark Platform for Embodied Agent in Real-world City Environment
EmbodiedCity: A Benchmark Platform for Embodied Agent in Real-world City Environment Open
Embodied artificial intelligence emphasizes the role of an agent's body in generating human-like behaviors. The recent efforts on EmbodiedAI pay a lot of attention to building up machine learning models to possess perceiving, planning, and…
View article: CircBIRC6 affects prostate cancer progression by regulating miR-574-5p and DNAJB1
CircBIRC6 affects prostate cancer progression by regulating miR-574-5p and DNAJB1 Open
CircBIRC6 is highly expressed in prostate cancer samples. Knockdown of its expression inhibits cell proliferation, invasion, EMT and autophagy and promotes apoptosis. CircBIRC6/miRNA-574-5p/DNAJB1 is a molecular axis that regulates prostat…
View article: Exploring the prognostic analysis of autophagy and tumor microenvironment based on monocyte cells in lung cancer
Exploring the prognostic analysis of autophagy and tumor microenvironment based on monocyte cells in lung cancer Open
A deep understanding of the biological mechanisms of lung cancer offers more precise treatment options for patients. In our study, we integrated data from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) to investigate …
View article: The regulation of MFG‐E8 on the mitophagy in diabetic sarcopenia via the HSPA1L‐Parkin pathway and the effect of D‐pinitol
The regulation of MFG‐E8 on the mitophagy in diabetic sarcopenia via the HSPA1L‐Parkin pathway and the effect of D‐pinitol Open
Background Diabetic sarcopenia is a disease‐related skeletal muscle disorder that causes progressive symptoms. The complete understanding of its pathogenesis is yet to be unravelled, which makes it difficult to develop effective therapeuti…
View article: Comparison of SEEKflex Combined with Videolaryngoscopy and Flexible Bronchoscopy for Awake Tracheal Intubation: A Randomized Clinical Trial
Comparison of SEEKflex Combined with Videolaryngoscopy and Flexible Bronchoscopy for Awake Tracheal Intubation: A Randomized Clinical Trial Open
View article: Dual H 2 O 2 /GSH-Sensitive MnO 2 -Coated Mesoporous Silica Nanoreactor Fabrication with Saikosaponin-d Loading for Hypoxia Alleviation Enhancing Thyroid Carcinoma Chemotherapy
Dual H 2 O 2 /GSH-Sensitive MnO 2 -Coated Mesoporous Silica Nanoreactor Fabrication with Saikosaponin-d Loading for Hypoxia Alleviation Enhancing Thyroid Carcinoma Chemotherapy Open
The O 2 -dependent chemotherapy usually exhibits limited therapeutic efficiency toward hypoxic solid tumors because of inadequate O 2 supply in tumor vasculature. Hence, an O 2 -elevated nanoplatform for delivering chemotherapeutics and er…
View article: Design and Simulation Optimization of an Ultra-Low Specific On-Resistance LDMOS Device
Design and Simulation Optimization of an Ultra-Low Specific On-Resistance LDMOS Device Open
The design of LDMOS (Lateral double diffused metal oxide semiconductor) devices with CFP (Contact field plate) has been of great significance in recent years, according to its advantages of low resistance and high switch efficiency. In thi…
View article: Plasma metabolomic signatures of breast cancer
Plasma metabolomic signatures of breast cancer Open
Background Breast cancer is a common malignant tumor. A large number of medical evidence shows that breast cancer screening can improve the early diagnosis rate and reduce the mortality rate of breast cancer. In the present study, a wide r…
View article: TGF-β1 mediates tumor immunosuppression aggravating at the late stage post-high-light-dose photodynamic therapy
TGF-β1 mediates tumor immunosuppression aggravating at the late stage post-high-light-dose photodynamic therapy Open
View article: Data from Inhibition of mTORC2 Induces Cell-Cycle Arrest and Enhances the Cytotoxicity of Doxorubicin by Suppressing MDR1 Expression in HCC Cells
Data from Inhibition of mTORC2 Induces Cell-Cycle Arrest and Enhances the Cytotoxicity of Doxorubicin by Suppressing MDR1 Expression in HCC Cells Open
mTOR is aberrantly activated in hepatocellular carcinoma (HCC) and plays pivotal roles in tumorigenesis and chemoresistance. Rapamycin has been reported to exert antitumor activity in HCC and sensitizes HCC cells to cytotoxic agents. Howev…
View article: Hypoxia Pathway in Osteoporosis: Laboratory Data for Clinical Prospects
Hypoxia Pathway in Osteoporosis: Laboratory Data for Clinical Prospects Open
The hypoxia pathway not only regulates the organism to adapt to the special environment, such as short-term hypoxia in the plateau under normal physiological conditions, but also plays an important role in the occurrence and development of…
View article: NTRK Mutation Promote Cancer Immunity and the Efficacy of Immune Checkpoint Blockade
NTRK Mutation Promote Cancer Immunity and the Efficacy of Immune Checkpoint Blockade Open
View article: Ru-Ruo2 Nano-Heterostructures Stabilized by the Sacrificing Oxidation Strategy of Mn3o4 Substrate for Boosting Acidic Oxygen Evolution Reaction
Ru-Ruo2 Nano-Heterostructures Stabilized by the Sacrificing Oxidation Strategy of Mn3o4 Substrate for Boosting Acidic Oxygen Evolution Reaction Open
View article: Immunotherapy response and microenvironment provide biomarkers of immunotherapy options for patients with lung adenocarcinoma
Immunotherapy response and microenvironment provide biomarkers of immunotherapy options for patients with lung adenocarcinoma Open
Background: Immunotherapy has been a promising approach option for lung cancer. Method: All the open-accessed data was obtained from the Cancer Genome Atlas (TCGA) database. All the analysis was conducted using the R software analysis. Res…
View article: Development and Validation of a Novel Ferroptosis-Related LncRNA Signature for Predicting Prognosis and the Immune Landscape Features in Uveal Melanoma
Development and Validation of a Novel Ferroptosis-Related LncRNA Signature for Predicting Prognosis and the Immune Landscape Features in Uveal Melanoma Open
Background Ferroptosis is a newly iron-dependent mode of programmed cell death that is involved in a variety of malignancies. But no research has shown a link between ferroptosis-related long non-coding RNAs (FRLs) and uveal melanoma (UM).…
View article: Integrative Analysis Identified MCT4 as an Independent Prognostic Factor for Bladder Cancer
Integrative Analysis Identified MCT4 as an Independent Prognostic Factor for Bladder Cancer Open
Background Bladder cancer is the 10th most common cancer and most common urothelial malignancy worldwide. Prognostic biomarkers for bladder cancer patients are required for individualized treatment. Monocarboxylate transporter 4 (MCT4), en…
View article: A Novel Prognostic Model Based on Ferroptosis-Related Gene Signature for Bladder Cancer
A Novel Prognostic Model Based on Ferroptosis-Related Gene Signature for Bladder Cancer Open
Background Bladder cancer (BC) is a molecular heterogeneous malignant tumor; the treatment strategies for advanced-stage patients were limited. Therefore, it is vital for improving the clinical outcome of BC patients to identify key biomar…
View article: Exosomes Derived From Adipose-Derived Mesenchymal Stem Cells Ameliorate Radiation-Induced Brain Injury by Activating the SIRT1 Pathway
Exosomes Derived From Adipose-Derived Mesenchymal Stem Cells Ameliorate Radiation-Induced Brain Injury by Activating the SIRT1 Pathway Open
Objective Studies have shown that the therapeutic effects of mesenchymal stem cells (MSCs) are mediated in a paracrine manner, mainly through extracellular vesicles such as exosomes. Here, we designed a study to investigate whether exosome…
View article: Association of CYP24A1 gene polymorphism with colorectal cancer in the Jiamusi population
Association of CYP24A1 gene polymorphism with colorectal cancer in the Jiamusi population Open
Background The population in Jiamusi has been reported to have the highest prevalence of colorectal cancer (CRC) in China. The genetic causal-effect for this occurrence among the residents remains unclear. Given the long cold seasons with …
View article: Lung cancer combined with diffuse peritoneal and mesenteric amyloidosis detected on 18F-FDG PET/CT
Lung cancer combined with diffuse peritoneal and mesenteric amyloidosis detected on 18F-FDG PET/CT Open
Rationale: Amyloidosis is a heterogeneous group of diseases characterized by extracellular deposition of amyloid fibrils. Lung carcinoma is rarely reported to be associated with AA amyloidosis. With regard to the manifestation of amyloidos…
View article: Phantom and clinical assessment of small pulmonary nodules using Q.Clear reconstruction on a silicon-photomultiplier-based time-of-flight PET/CT system
Phantom and clinical assessment of small pulmonary nodules using Q.Clear reconstruction on a silicon-photomultiplier-based time-of-flight PET/CT system Open
View article: Contributors
Contributors Open
View article: Does the beta regularization parameter of bayesian penalized likelihood reconstruction always affect the quantification accuracy and image quality of positron emission tomography computed tomography?
Does the beta regularization parameter of bayesian penalized likelihood reconstruction always affect the quantification accuracy and image quality of positron emission tomography computed tomography? Open
Purpose This study aims to provide a detailed investigation on the noise penalization factor in Bayesian penalized likelihood (BPL)‐based algorithm, with the utilization of partial volume effect correction (PVC), so as to offer the suitabl…