Bal Krishna Ojha
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View article: An Integrative Analysis of O6-Methylguanine-DNA Methyltransferase (MGMT) Methylation and the Single-Nucleotide Polymorphism (SNP) rs1625649 Reveals Distinct Survival Patterns in Glioblastoma: A Retrospective Study
An Integrative Analysis of O6-Methylguanine-DNA Methyltransferase (MGMT) Methylation and the Single-Nucleotide Polymorphism (SNP) rs1625649 Reveals Distinct Survival Patterns in Glioblastoma: A Retrospective Study Open
View article: Study of Motor Evoked Potential on Intraoperative Neurophysiological Monitoring Cases of Neurosurgeries
Study of Motor Evoked Potential on Intraoperative Neurophysiological Monitoring Cases of Neurosurgeries Open
Background: Motor evoked potential (MEP) monitoring is crucial in intraoperative neurophysiological monitoring (IONM) during neurosurgeries, but its effectiveness is influenced by factors such as anesthesia type, patient condition, and sur…
View article: Enhanced framework for credit card fraud detection using robust feature selection and a stacking ensemble model approach
Enhanced framework for credit card fraud detection using robust feature selection and a stacking ensemble model approach Open
View article: Immunohistochemical expression of PDL1 and Ki67 in glioma and its correlation with treatment and overall survival
Immunohistochemical expression of PDL1 and Ki67 in glioma and its correlation with treatment and overall survival Open
Context: Gliomas are the most common primary brain tumors with an infiltrative nature; hence, complete removal is difficult, and despite radiotherapy and chemotherapy, there have been a high recurrence and poor survival rates. Hence, novel…
View article: Management of intracranial meningioma: Outcome analysis and clinico radiological profile of 172 patients
Management of intracranial meningioma: Outcome analysis and clinico radiological profile of 172 patients Open
Background: Meningioma is the most common primary intracranial tumor. This single-center study aimed to analyze the clinicopathological, radiological profile, and outcomes of patients with intracranial meningiomas in terms of functional st…
View article: Retrospective Outcome Analysis of Geriatric Traumatic Brain Injury Treated at a Tertiary Care Center in India
Retrospective Outcome Analysis of Geriatric Traumatic Brain Injury Treated at a Tertiary Care Center in India Open
Trauma is a major cause of morbidity and mortality in elderly patients and its management is challenging. Outcome assessment in these patients is difficult because of preexisting chronic medical conditions as it may be impossible to isolat…
View article: Utilizing squash cytology and histodiagnosis to detect lipomatous metaplasia in meningiomas: A diagnostic approach
Utilizing squash cytology and histodiagnosis to detect lipomatous metaplasia in meningiomas: A diagnostic approach Open
Squash smears provide with preliminary cytological diagnosis in central nervous lesions. Reporting features of uncommon lesions is important for correct identification of them. We herewith present a case of meningioma with lipomatous metap…
View article: Expression of isocitrate dehydrogenase 1 and tumor protein 53 in high-grade glioma and its correlation with the outcome – A prospective study at a tertiary care center in India
Expression of isocitrate dehydrogenase 1 and tumor protein 53 in high-grade glioma and its correlation with the outcome – A prospective study at a tertiary care center in India Open
Background: Central nervous system tumors are the 10th most prevalent cause of mortality worldwide. The 2016 World Health Organization (WHO) classification of high grade gliomas (HGG) has identified Isocitrate dehydrogenase 1 (IDH 1) mutat…
View article: Expression of isocitrate dehydrogenase 1 and tumor protein 53 in high-grade glioma and its correlation with the outcome – A prospective study at a tertiary care center in India
Expression of isocitrate dehydrogenase 1 and tumor protein 53 in high-grade glioma and its correlation with the outcome – A prospective study at a tertiary care center in India Open
Background: Central nervous system tumors are the 10th most prevalent cause of mortality worldwide. The 2016 World Health Organization (WHO) classification of high grade gliomas (HGG) has identified Isocitrate dehydrogenase 1 (IDH 1) mutat…
View article: Clinical Outcome and Predictors of Traumatic Cervical Injury: A Prospective Observational Study
Clinical Outcome and Predictors of Traumatic Cervical Injury: A Prospective Observational Study Open
Introduction Traumatic cervical spine injuries (CSIs) have an incidence of 1.7 to 8% among traumatic brain injury (TBI) patients and should be a pivotal part of its neurological examination. Prognosis of cervical spine insult in TBI depend…
View article: A Routine Procedure with Rare Complication of Cranial Migration of VP Shunt (Chabra Shunt): A Series of Three Cases
A Routine Procedure with Rare Complication of Cranial Migration of VP Shunt (Chabra Shunt): A Series of Three Cases Open
A bstract Cranial migration of the shunt assembly is a rare complication following ventricular-peritoneal (VP) shunting, a common treatment for hydrocephalus. Despite its prevalence, VP shunting is associated with numerous complications, s…
View article: Diagnostic approach to a rare case of anaplastic meningioma with osteosarcomatous differentiation and associated bone alterations
Diagnostic approach to a rare case of anaplastic meningioma with osteosarcomatous differentiation and associated bone alterations Open
Anaplastic meningioma with osteosarcomatous differentiation is a very rare finding. We herewith present squash cytology, histopathology and immunohistochemistry findings of this rare case with systematic approach to diagnosis. A 38-year-ol…
View article: Surgical Outcomes and Predictive Factor Analysis for Facial Nerve Preservation in Patients With Cerebellopontine Angle (CPA) Tumors: A Ten-Year Single Institutional Study
Surgical Outcomes and Predictive Factor Analysis for Facial Nerve Preservation in Patients With Cerebellopontine Angle (CPA) Tumors: A Ten-Year Single Institutional Study Open
Objective To analyze the surgical outcome and predictive factors for facial nerve preservation in patients with surgically operated cerebellopontine angle (CPA) tumors. Methodology Methodology Data were retrospectively retrieved from inpat…
View article: A Glimpse into the Prognostic Factors of Outcomes for Isolated, Operated Severe Traumatic Head Injury Patients in a Resource Constrained Trauma Center Setup
A Glimpse into the Prognostic Factors of Outcomes for Isolated, Operated Severe Traumatic Head Injury Patients in a Resource Constrained Trauma Center Setup Open
Severe traumatic brain injury (STBI) continues to burden health care in developing countries. This study focuses on STBI patients undergoing surgical intervention to understand the factors affecting their outcomes in a constrained trauma c…
View article: Variations of Tentorial Notch Anatomy in Autopsy and NCCT of Head Injury Patients to Correlate Its Impact over Brainstem—An Observational Study
Variations of Tentorial Notch Anatomy in Autopsy and NCCT of Head Injury Patients to Correlate Its Impact over Brainstem—An Observational Study Open
Tentorium cerebelli divide cranial cavity into supratentorial and infratentorial compartment. Tentorial notch is a gap in tentorium cerebelli located centrally and anteriorly, related to upper brainstem, first six cranial nerves, cerebrum,…
View article: Clinical course and treatment challenges in post-COVID-19 rhino-orbital-cerebral mucormycosis in an immunocompetent host: A case report
Clinical course and treatment challenges in post-COVID-19 rhino-orbital-cerebral mucormycosis in an immunocompetent host: A case report Open
The aggressive and invasive nature of rhino-orbital-cerebral mucormycosis (ROCM) in immunocompromised patients is well documented. However, this case report aims to narrate its progression in an immunocompetent patient post-recovery from C…
View article: An Interesting Case of Penetrating Brain Injury Due to Assault with Meat Chopper Knife
An Interesting Case of Penetrating Brain Injury Due to Assault with Meat Chopper Knife Open
Penetrating injuries to brain are rare and mostly result from warfare injuries, suicidal/homicidal firearm injuries, or accidental injuries. In general, they are associated with poor outcome. We report the challenges faced in managing an i…
View article: Cranial Migration of a VP Shunt—A Routine Procedure with a Rare Complication!
Cranial Migration of a VP Shunt—A Routine Procedure with a Rare Complication! Open
Ventriculoperitoneal shunt is one of the commonest neurosurgical procedures associated with a high-rate complication. Moreover, the variety of complications are nonetheless astonishing. Shunt malfunction is considered the most common compl…
View article: Is basal cisternostomy in traumatic brain injury a need of hour or white elephant – A randomized trial to answer
Is basal cisternostomy in traumatic brain injury a need of hour or white elephant – A randomized trial to answer Open
Background: Basal cisternostomy (BC) recently emerged as an adjuvant/alternative procedure to decompressive craniectomy (DC) in traumatic brain injuries (TBIs) with its potential to effectively reduce both intracranial pressure (ICP) and b…
View article: A Rare Case of Pediatric Suprasellar - Sellar Ependymona: Case Report & Review of Literature
A Rare Case of Pediatric Suprasellar - Sellar Ependymona: Case Report & Review of Literature Open
Introduction: Ependymomas are common brain tumors in children. They are usually found in the posterior fossa (60%), supratentorial region (30%), and spine around the ependyma of ventricles or spinal canal as they arise from the ependymal l…
View article: A comparative study of Outcome in Ventriculoperitoneal Shunt and Endoscopic Third Ventriculostomy in Cases of Tubercular Meningitis with Hydrocephalus in Pediatric Patients
A comparative study of Outcome in Ventriculoperitoneal Shunt and Endoscopic Third Ventriculostomy in Cases of Tubercular Meningitis with Hydrocephalus in Pediatric Patients Open
Introduction: Tuberculous meningitis (TBM) is becoming a rare illness in industrialized nations, but it is still widespread in underdeveloped nations. Ventriculoperitoneal shunt surgery is the GOLD Standard and is time tested procedure. Sh…
View article: Medulloblastoma and ABO-Rh Blood Group: Evidence of an Association between the Distribution of Blood Group Antigens and Medulloblastoma
Medulloblastoma and ABO-Rh Blood Group: Evidence of an Association between the Distribution of Blood Group Antigens and Medulloblastoma Open
Objective Medulloblastoma is the most common central nervous system embryonal tumor and the most common malignant brain tumor of childhood. This study aims to find out the incidence of the ABO-Rh blood group in medulloblastoma patients of …
View article: Gender Differences in Executive Functions of Patients Operated for Mild to Moderate Epidural Hematoma
Gender Differences in Executive Functions of Patients Operated for Mild to Moderate Epidural Hematoma Open
Background Impairment in neurocognitive functions are commonly followed by Epidural hematoma (EDH) . This cross-sectional study was aimed to study gender differences in neurocognitive functions in mild to moderate epidural hematoma patient…
View article: Pediatric Cervical Spine Injuries
Pediatric Cervical Spine Injuries Open
Objective Pediatric cervical spine injuries are rare and account for 1 to 2% of all pediatric spine injuries. There is a paucity of data on pediatric cervical spine injuries in developing countries like India. The purpose of this study is …
View article: Effect of Lockdown on Neurosurgery Trauma Patients in a Tertiary Care Hospital in India
Effect of Lockdown on Neurosurgery Trauma Patients in a Tertiary Care Hospital in India Open
Background With an increasing number of cases of COVID-19 disease, the Indian government announced a complete lockdown on March 24, 2020, and the country remained under complete lockdown in April 2020. After ramping up health infrastructur…
View article: COVID-19 cases and their outcome among patients with uncommon co-existing illnesses: A lesson from Northern India
COVID-19 cases and their outcome among patients with uncommon co-existing illnesses: A lesson from Northern India Open
In Indian settings, comorbidities like tuberculosis and bacterial infections can precipitate severe COVID 19 unlike other parts of the world where tuberculosis is relatively uncommon.
View article: Phytomolecules: A potential bioenhancer for pharmaceutical drugs
Phytomolecules: A potential bioenhancer for pharmaceutical drugs Open
Phyto-bioenhancer is an agent of herbal origin, which is capable of enhancing bio-availability and bio-efficacy of a particular drug or nutrient with which it is combined, without any typical pharmacological activity of its own at the dose…
View article: Infections Associated With Indwelling Cns Devices In Neurosurgical Patients
Infections Associated With Indwelling Cns Devices In Neurosurgical Patients Open
View article: COVID-19 associated mucormycosis: Staging and management recommendations (Report of a multi-disciplinary expert committee)
COVID-19 associated mucormycosis: Staging and management recommendations (Report of a multi-disciplinary expert committee) Open
View article: Patterns of Orbital Fractures Needing Surgical Reconstruction in a Large Tertiary Hospital in Northern India
Patterns of Orbital Fractures Needing Surgical Reconstruction in a Large Tertiary Hospital in Northern India Open
Study Design: This is a prospective study for 3 year duration. Objective: The aim of this study was to observe the incidence and patterns of orbital fractures and discuss their treatment options. Methods: A total 29604 trauma patients visi…