Balaji Tamarappoo
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View article: Evaluation of ePLAR, the echocardiographic pulmonary to left atrial ratio, in a large cohort with pulmonary hypertension
Evaluation of ePLAR, the echocardiographic pulmonary to left atrial ratio, in a large cohort with pulmonary hypertension Open
Background and Aims Pre-capillary pulmonary hypertension (PHTN), typically due to intrinsic pulmonary pathology, requires right heart catheterization (RHC) for diagnosis. ePLAR, the echocardiographic pulmonary to left atrial ratio (calcula…
View article: Diagnostic and Prognostic Value of High‐Sensitivity Troponin T for Cardiovascular Outcomes in Patients Receiving Immune Checkpoint Inhibitor Therapy
Diagnostic and Prognostic Value of High‐Sensitivity Troponin T for Cardiovascular Outcomes in Patients Receiving Immune Checkpoint Inhibitor Therapy Open
Background Immune‐checkpoint inhibitors (ICI) are associated with adverse cardiac events. Although troponin elevation is a diagnostic criterion for ICI‐related myocarditis (ICIrM) and myocardial infarction, data on other causes of troponin…
View article: A cross-sectional comparison of invasive and noninvasive aortic pulse wave velocity measurement in patients with or at risk for heart failure with preserved ejection fraction
A cross-sectional comparison of invasive and noninvasive aortic pulse wave velocity measurement in patients with or at risk for heart failure with preserved ejection fraction Open
MRI measurement of aPWV shows good agreement with traditional invasive and noninvasive measurements in participants with or at risk for HFpEF. Reliable measurement of arterial stiffness combined with cardiac MRI measures of ventricular rem…
View article: Glucagon-like peptide-1 receptor agonists in patients with anthracycline related cardiac dysfunction
Glucagon-like peptide-1 receptor agonists in patients with anthracycline related cardiac dysfunction Open
In cancer patients with anthracycline induced CTRCD, those treated with GLP-1RAs had significantly lower risk of adverse clinical outcomes.
View article: Computed Tomography and Coronary Plaque Analysis
Computed Tomography and Coronary Plaque Analysis Open
Advances in plaque imaging have transformed cardiovascular diagnostics through detailed characterization of atherosclerotic plaques beyond traditional stenosis assessment. This review outlines the clinical applications of varying modalitie…
View article: Subclinical Atherosclerosis and Cardiovascular Events Among Patients With Colorectal Cancer
Subclinical Atherosclerosis and Cardiovascular Events Among Patients With Colorectal Cancer Open
Background Prior studies have documented that patients with colorectal cancer (CRC) are at an increased risk of cardiovascular disease (CVD). Objectives To examine coronary artery calcium (CAC) as a marker of subclinical atherosclerosis an…
View article: Utility of Cardiac CT for Cardiomyopathy Phenotyping
Utility of Cardiac CT for Cardiomyopathy Phenotyping Open
Cardiac computed tomography (CT) has rapidly advanced, becoming an invaluable tool for diagnosing and prognosticating various cardiovascular diseases. While echocardiography and cardiac magnetic resonance imaging (CMR) remain the gold stan…
View article: Intracoronary acetylcholine for vasospasm provocation in women with ischemia and no obstructive coronary artery disease
Intracoronary acetylcholine for vasospasm provocation in women with ischemia and no obstructive coronary artery disease Open
Among women with suspected INOCA, intracoronary Ach spasm testing provoked epicardial vasospasm in one fourth. Women with epicardial vasospasm overwhelmingly had concomitant endothelial dysfunction, worse QoL but not more frequent myocardi…
View article: Applications of Artificial Intelligence for the Prediction and Diagnosis of Cancer Therapy-Related Cardiac Dysfunction in Oncology Patients
Applications of Artificial Intelligence for the Prediction and Diagnosis of Cancer Therapy-Related Cardiac Dysfunction in Oncology Patients Open
Cardiovascular diseases and cancer are the leading causes of morbidity and mortality in modern society. Expanding cancer therapies that have improved prognosis may also be associated with cardiotoxicity, and extended life span after surviv…
View article: Worse ischemic symptoms and cardiac function in women with suspected ischemia with no obstructive coronary artery disease and adverse pregnancy outcomes history
Worse ischemic symptoms and cardiac function in women with suspected ischemia with no obstructive coronary artery disease and adverse pregnancy outcomes history Open
Background Adverse pregnancy outcomes (APO) are associated with increased maternal risk of cardiovascular disease (CVD) and mortality. Ischemia with no obstructive coronary artery disease (INOCA) is predominant in women, however the associ…
View article: Patient-Specific Myocardial Infarction Risk Thresholds From AI-Enabled Coronary Plaque Analysis
Patient-Specific Myocardial Infarction Risk Thresholds From AI-Enabled Coronary Plaque Analysis Open
BACKGROUND: Plaque quantification from coronary computed tomography angiography has emerged as a valuable predictor of cardiovascular risk. Deep learning can provide automated quantification of coronary plaque from computed tomography angi…
View article: Quantification of Aortic Valve Fibrotic and Calcific Tissue from CTA: Prospective Comparison with Histology
Quantification of Aortic Valve Fibrotic and Calcific Tissue from CTA: Prospective Comparison with Histology Open
In participants with aortic stenosis, semiautomated quantification of aortic valve fibrotic and calcific tissue composition at CT angiography showed excellent concordance with histologic findings and demonstrated interobserver reproducibil…
View article: Chemotherapy Related Cardiotoxicity Evaluation—A Contemporary Review with a Focus on Cardiac Imaging
Chemotherapy Related Cardiotoxicity Evaluation—A Contemporary Review with a Focus on Cardiac Imaging Open
The long-term survivorship of patients diagnosed with cancer has improved due to accelerated detection and rapidly evolving cancer treatment strategies. As such, the evaluation and management of cancer therapy related complications has bec…
View article: Variation of computed tomography-derived extracellular volume fraction and the impact of protocol parameters: A systematic review and meta-analysis
Variation of computed tomography-derived extracellular volume fraction and the impact of protocol parameters: A systematic review and meta-analysis Open
CT-ECV estimates for healthy individuals vary widely in the literature and there is significant overlap with estimates in cardiac disease. One quarter of this heterogeneity is explained by differences in CT-ECV protocol parameters. Standar…
View article: MRI in Patients with Cardiovascular Implantable Electronic Devices and Fractured or Abandoned Leads
MRI in Patients with Cardiovascular Implantable Electronic Devices and Fractured or Abandoned Leads Open
Purpose To examine the clinical effect of lead length and lead orientation in patients with cardiac implantable electronic devices (CIEDs) and lead fragments or abandoned leads undergoing 1.5-T MRI. Materials and Methods This Health Insura…
View article: Soft tissue displacement for detection of left ventricle apical dyskinesis with transthoracic echocardiography
Soft tissue displacement for detection of left ventricle apical dyskinesis with transthoracic echocardiography Open
We tested the hypothesis that the use of outward displacement of the soft tissue between the apex and the chest wall as seen in TTE, is a sign of apical displacement and would allow for more accurate diagnosis of apical dyskinesis. This is…