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View article: Matching‐adjusted indirect comparisons of efficacy and safety for zanubrutinib versus the combination of fixed‐duration venetoclax and ibrutinib in patients with treatment‐naïve chronic lymphocytic leukaemia
Matching‐adjusted indirect comparisons of efficacy and safety for zanubrutinib versus the combination of fixed‐duration venetoclax and ibrutinib in patients with treatment‐naïve chronic lymphocytic leukaemia Open
View article: Complex Characterization of Cerebral Vasoreactivity in Internal Carotid Artery Stenotic Patients with Transcranial Doppler Sonography
Complex Characterization of Cerebral Vasoreactivity in Internal Carotid Artery Stenotic Patients with Transcranial Doppler Sonography Open
Background and Aims: Decreased cerebrovascular reactivity (CVR) in patients with significant internal carotid artery stenosis (ICAS ≥ 70%) is an independent risk factor for cerebral infarction. To evaluate CVR, changes in cerebral perfusio…
View article: Indirect Comparisons of the Efficacy and Safety of Zanubrutinib versus Venetoclax plus Obinutuzumab in Treatment-Naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Indirect Comparisons of the Efficacy and Safety of Zanubrutinib versus Venetoclax plus Obinutuzumab in Treatment-Naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Open
SEQUOIA (NCT03336333); CLL14 (NCT02242942).
View article: Histopathological Changes of the Corticospinal Tract Following Hemorrhagic and Ischemic Stroke
Histopathological Changes of the Corticospinal Tract Following Hemorrhagic and Ischemic Stroke Open
Previous data on the time course of corticospinal tract (CST) degeneration after stroke are scarce, especially in the early phase. Using post-mortem histomorphological and immunohistochemical methods, CST degeneration (its temporal dynamic…
View article: Indirect treatment comparisons of momelotinib vs pacritinib safety and anemia outcomes in patients with myelofibrosis
Indirect treatment comparisons of momelotinib vs pacritinib safety and anemia outcomes in patients with myelofibrosis Open
Momelotinib provides a more favorable safety profile and a higher chance for hemoglobin improvement vs pacritinib.
View article: 209 | EFFICACY OF CONTINUOUS ZANUBRUTINIB VERSUS FIXED‐DURATION VENETOCLAX IN COMBINATION WITH OBINUTUZUMAB IN TREATMENT‐NAIVE CLL: A MATCHING‐ADJUSTED INDIRECT COMPARISON
209 | EFFICACY OF CONTINUOUS ZANUBRUTINIB VERSUS FIXED‐DURATION VENETOCLAX IN COMBINATION WITH OBINUTUZUMAB IN TREATMENT‐NAIVE CLL: A MATCHING‐ADJUSTED INDIRECT COMPARISON Open
View article: The Prognostic Value of Biomarkers and the Effect of Tolperisone in Acute Low Back Pain - BETA. Rationale, Study Design and Statistical Analysis Plan for a Randomized, Placebo-Controlled, Double Blind Study
The Prognostic Value of Biomarkers and the Effect of Tolperisone in Acute Low Back Pain - BETA. Rationale, Study Design and Statistical Analysis Plan for a Randomized, Placebo-Controlled, Double Blind Study Open
View article: Rationale, Study Design and Statistical Analysis Plan for a Trial on the Prognostic Value of Biomarkers and the Effect of Tolperisone in Acute Low Back Pain - Beta. A Phase 3 Investigator Initiated Randomized, Placebo-Controlled, Double Blind Study
Rationale, Study Design and Statistical Analysis Plan for a Trial on the Prognostic Value of Biomarkers and the Effect of Tolperisone in Acute Low Back Pain - Beta. A Phase 3 Investigator Initiated Randomized, Placebo-Controlled, Double Blind Study Open
View article: MPN-092 Indirect Treatment Comparisons of Momelotinib vs Pacritinib Safety and Anemia Outcomes in Patients With Myelofibrosis
MPN-092 Indirect Treatment Comparisons of Momelotinib vs Pacritinib Safety and Anemia Outcomes in Patients With Myelofibrosis Open
View article: POSTER: MPN-092 Indirect Treatment Comparisons of Momelotinib vs Pacritinib Safety and Anemia Outcomes in Patients With Myelofibrosis
POSTER: MPN-092 Indirect Treatment Comparisons of Momelotinib vs Pacritinib Safety and Anemia Outcomes in Patients With Myelofibrosis Open
View article: P1057: INDIRECT TREATMENT COMPARISONS OF MOMELOTINIB VS PACRITINIB SAFETY AND ANEMIA OUTCOMES IN PATIENTS WITH MYELOFIBROSIS
P1057: INDIRECT TREATMENT COMPARISONS OF MOMELOTINIB VS PACRITINIB SAFETY AND ANEMIA OUTCOMES IN PATIENTS WITH MYELOFIBROSIS Open
Topic: 16. Myeloproliferative neoplasms - Clinical Background: JAK inhibitors (JAKi) are effective in the management of symptoms and splenomegaly in patients (pts) with myelofibrosis (MF) but have varying safety profiles and may be associa…
View article: Ponatinib vs. Imatinib as Frontline Treatment for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: A Matching Adjusted Indirect Comparison
Ponatinib vs. Imatinib as Frontline Treatment for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: A Matching Adjusted Indirect Comparison Open
View article: Markov Chain-Based Cost-Optimal Control Charts with Applications in Health Care
Markov Chain-Based Cost-Optimal Control Charts with Applications in Health Care Open
View article: Markovchart: an R package for cost-optimal patient monitoring and treatment using control charts
Markovchart: an R package for cost-optimal patient monitoring and treatment using control charts Open
View article: A Note on the Moments of Special Mixture Distributions, with Applications for Control Charts
A Note on the Moments of Special Mixture Distributions, with Applications for Control Charts Open
Control charts can be applied in a wide range of areas, this paper focuses on generalisations suitable for healthcare applications. We concentrate on the effect of using mixture distributions as the possible shifts in the process mean valu…
View article: Impact of COVID-19 on ischemic stroke care in Hungary
Impact of COVID-19 on ischemic stroke care in Hungary Open
Data about the coronavirus disease 2019 (COVID-19) pandemic’s collateral damage on ischemic stroke (IS) care during the second epidemic wave in Central Europe are limited. We sought to evaluate the impact of the COVID-19 outbreak on Hungar…
View article: Randomised Markovchart patient data
Randomised Markovchart patient data Open
Randomised diabetes patient data example for use in Markovchart-type control charts: https://cran.r-project.org/web/packages/Markovchart/index.html
View article: A hazai sclerosis multiplex betegpopuláció életkori és nemi megoszlása 2004 és 2016 között
A hazai sclerosis multiplex betegpopuláció életkori és nemi megoszlása 2004 és 2016 között Open
Összefoglaló. Bevezetés: Mivel hazánkban a sclerosis multiplex gyakoriságáról, valamint életkori és nemi jellegzetességeiről az elmúlt évtizedekben – egészen 2020-ig – csak regionális jellegű felmérések készültek egy-egy centrum betegforga…
View article: Health related quality of life and satisfaction with care of stroke patients in Budapest: A substudy of the EuroHOPE project
Health related quality of life and satisfaction with care of stroke patients in Budapest: A substudy of the EuroHOPE project Open
In addition to age, disability, and satisfaction with care, length of hospital stay and type of social dwelling after stroke also predicted HRQoL. Long-term outcome after stroke could be improved by reducing time spent in hospital, i.e. by…
View article: Socioeconomic Factors Predicting Depression Differ in the Acute Stage and at 1 year After Ischemic Stroke or TIA
Socioeconomic Factors Predicting Depression Differ in the Acute Stage and at 1 year After Ischemic Stroke or TIA Open
Predictors of the severity of depressive symptoms differed in the acute phase and at follow-up. In addition to disability, education and employment status in the acute phase and income in the late phase predict the severity of depressive s…
View article: The prevalence of psychiatric symptoms before the diagnosis of Parkinson’s disease in a nationwide cohort: A comparison to patients with cerebral infarction
The prevalence of psychiatric symptoms before the diagnosis of Parkinson’s disease in a nationwide cohort: A comparison to patients with cerebral infarction Open
The higher rate of psychiatric morbidity in the premotor phase of PD may reflect neurotransmitter changes in the early phase of PD.
View article: Incidence and prevalence of multiple sclerosis in Hungary based on record linkage of nationwide multiple healthcare administrative data
Incidence and prevalence of multiple sclerosis in Hungary based on record linkage of nationwide multiple healthcare administrative data Open
The prevalence of MS in Hungary is higher than previously reported, the incidence rate is moderate. The prevalence is rising, the incidence rate shows decline. The proportion of patients receiving disease modifying treatment grows but was …
View article: Notification Strategy and Predictors of Outcome in Stroke Ineligible for Reperfusion Therapies
Notification Strategy and Predictors of Outcome in Stroke Ineligible for Reperfusion Therapies Open
Background, Objective: At least 70% of all stroke patients are ineligible for recanalization therapy. We identified predictors of outcome among these patients, with special focus on notification of emergency medical services (EMS). …
View article: Markov chain‐based cost‐optimal control charts for health care data
Markov chain‐based cost‐optimal control charts for health care data Open
Control charts have traditionally been used in industrial statistics but are constantly seeing new areas of application, especially in the age of Industry 4.0. This paper introduces a new method, which is suitable for applications in the h…
View article: Markov chain-based cost-optimal control charts with different shift size distributions
Markov chain-based cost-optimal control charts with different shift size distributions Open
View article: Markov Chain-based Cost-Optimal Control Charts for Healthcare Data
Markov Chain-based Cost-Optimal Control Charts for Healthcare Data Open
Control charts have traditionally been used in industrial statistics but are constantly seeing new areas of application, especially in the age of Industry 4.0. This paper introduces a new method, which is suitable for applications in the h…