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View article: Fluke-borne viruses are a risk factor for diseases caused by carcinogenic trematodes
Fluke-borne viruses are a risk factor for diseases caused by carcinogenic trematodes Open
Three trematode parasites, Schistosoma haematobium, Opisthorchis viverrini and Clonorchis sinensis are recognized group 1 biological carcinogens. Herein, we showed that all three carcinogenic trematodes harbor viruses. Focusing on O. viver…
View article: A population genetic analysis of the nematode <i>Strongyloides stercoralis</i> in Asia shows that human infection is not a zoonosis from dogs
A population genetic analysis of the nematode <i>Strongyloides stercoralis</i> in Asia shows that human infection is not a zoonosis from dogs Open
Gut nematode worms are important parasites of people and other animals. The parasitic nematode Strongyloides stercoralis infects an estimated 600 million people worldwide and is one of the soil-transmitted helminthiases, a WHO-defined negl…
View article: Nationwide spatial dynamics of taeniasis in Thailand: declining prevalence but shifting focus and One Health risk factors across 2008–2014
Nationwide spatial dynamics of taeniasis in Thailand: declining prevalence but shifting focus and One Health risk factors across 2008–2014 Open
Background The prevalence of taeniasis in Thailand has decreased over the past six decades. However, it remains a public health concern, particularly in focal areas, especially along the border regions where migration between Thailand and …
View article: Immunomics-guided biomarker discovery for human liver fluke infection and infection-associated cholangiocarcinoma
Immunomics-guided biomarker discovery for human liver fluke infection and infection-associated cholangiocarcinoma Open
View article: The Global Prevalence of and Factors Associated with Parasitic Coinfection in People Living with Viruses: A Systematic Review and Meta-Analysis
The Global Prevalence of and Factors Associated with Parasitic Coinfection in People Living with Viruses: A Systematic Review and Meta-Analysis Open
Coinfection with parasites and viruses can exacerbate disease transmission, outcomes and therapy. This study searched the Web of Science, PubMed, Scopus and JSTOR databases for publications on the prevalence of parasitic coinfection in peo…
View article: Quantifying national burdens of foodborne disease—Four imperatives for global impact
Quantifying national burdens of foodborne disease—Four imperatives for global impact Open
Estimates of national burdens of the foodborne disease (FBD) inform country-level food safety policies, ranking infectious and non-infectious FBD hazards in terms of health and socioeconomic impact to mitigate FBD burdens. Using relevant p…
View article: Geospatial distribution and risk factors of <i>Strongyloides stercoralis</i> in rural communities of Northeast Thailand
Geospatial distribution and risk factors of <i>Strongyloides stercoralis</i> in rural communities of Northeast Thailand Open
Background Strongyloides stercoralis is a neglected soil‐transmitted helminth endemic in tropical and subtropical regions. This study aimed to determine the prevalence, risk factors, and spatial distribution of S. stercoralis infection in …
View article: Integrated opisthorchiasis control through the EcoHealth/one health approach: 15 years of success and experiences with the Lawa model
Integrated opisthorchiasis control through the EcoHealth/one health approach: 15 years of success and experiences with the Lawa model Open
Opisthorchis viverrini infection remains a major health problem in Northeast Thailand and the Mekong region impacting over 12 million and causing bile duct cancer. Using an EcoHealth/One Health approach at Lawa Lake in Thailand, our…
View article: Co-Occurrence of Leptospirosis and Opisthorchis Viverrini Infection in Cats and Their Risk Factors
Co-Occurrence of Leptospirosis and Opisthorchis Viverrini Infection in Cats and Their Risk Factors Open
View article: Updates on pathogenesis of Helicobacter pylori-Opisthorchis viverrini co-infections induced cholangiocarcinoma
Updates on pathogenesis of Helicobacter pylori-Opisthorchis viverrini co-infections induced cholangiocarcinoma Open
View article: Increased Insulin Resistance Following Praziquantel Treatment in Human Opisthorchiasis Caused by Opisthorchis Viverrini Infection
Increased Insulin Resistance Following Praziquantel Treatment in Human Opisthorchiasis Caused by Opisthorchis Viverrini Infection Open
View article: Leveraging Machine Learning for Predicting Opisthorchis Viverrini Infection in Cats: A Tool for Veterinary Epidemiology
Leveraging Machine Learning for Predicting Opisthorchis Viverrini Infection in Cats: A Tool for Veterinary Epidemiology Open
View article: <b>Knowledge gaps and risk behaviors among cat owners in <i>Opisthorchis viverrini</i> endemic areas: Implications for public health interventions</b>
<b>Knowledge gaps and risk behaviors among cat owners in <i>Opisthorchis viverrini</i> endemic areas: Implications for public health interventions</b> Open
Background: According to the World Health Organization’s “A roadmap for neglected tropical diseases 2021–2030,” controlling Opisthorchis viverrini infection in humans requires interventions targeting animal reservoirs, particularly cats an…
View article: One Health showcase from Asia: the Lawa model—a community-based approach to liver fluke control in Thailand
One Health showcase from Asia: the Lawa model—a community-based approach to liver fluke control in Thailand Open
Liver fluke infection caused by Opisthorchis viverrini is a significant public health challenge in the Lower Mekong Basin, affecting over 10 million people and leading to cholangiocarcinoma, a fatal bile duct cancer. Traditional con…
View article: Comparative liver transcriptome analysis in hamsters infected with food-borne trematodes Opisthorchis felineus, Opisthorchis viverrini, or Clonorchis sinensis
Comparative liver transcriptome analysis in hamsters infected with food-borne trematodes Opisthorchis felineus, Opisthorchis viverrini, or Clonorchis sinensis Open
Background Epidemiologically important food-borne trematodes Opisthorchis viverrini and Clonorchis sinensis are recognized as biological carcinogens of Group 1A, while Opisthorchis felineus is in Group 3 as noncarcinogenic to humans. Mecha…
View article: Species-specific renal and liver responses during infection with food-borne trematodes Opisthorchis felineus, Opisthorchis viverrini, or Clonorchis sinensis
Species-specific renal and liver responses during infection with food-borne trematodes Opisthorchis felineus, Opisthorchis viverrini, or Clonorchis sinensis Open
Three food-borne trematodes— Opisthorchis felineus , Opisthorchis viverrini , and Clonorchis sinensis —are closely related epidemiologically important species. Despite the similarity of their life cycles, these liver flukes also have marke…
View article: A population genetic analysis of the nematode <i>Strongyloides stercoralis</i> in Asia shows that human infection is not a zoonosis from dogs
A population genetic analysis of the nematode <i>Strongyloides stercoralis</i> in Asia shows that human infection is not a zoonosis from dogs Open
Gut nematode worms are important parasites of people and other animals. The parasitic nematode Strongyloides stercoralis infects an estimated 600 million people worldwide, and is one of the soil-transmitted helminthiases, a WHO-defined neg…
View article: A study protocol for a multi-country cluster randomized controlled trial of the impact of a multi-component One Health strategy to eliminate Opisthorchis viverrini and soil transmitted helminths in the Lower Mekong Basin
A study protocol for a multi-country cluster randomized controlled trial of the impact of a multi-component One Health strategy to eliminate Opisthorchis viverrini and soil transmitted helminths in the Lower Mekong Basin Open
View article: Examining the Acceptability of Helminth Education Packages “Magic Glasses Lower Mekong” and “Magic Glasses Opisthorchiasis” and Their Impact on Knowledge, Attitudes, and Practices Among Schoolchildren in the Lower Mekong Basin: Protocol for a Cluster Randomized Controlled Trial
Examining the Acceptability of Helminth Education Packages “Magic Glasses Lower Mekong” and “Magic Glasses Opisthorchiasis” and Their Impact on Knowledge, Attitudes, and Practices Among Schoolchildren in the Lower Mekong Basin: Protocol for a Cluster Randomized Controlled Trial Open
Background Helminths are a major global health issue, impacting health, educational, and socioeconomic outcomes. Infections, often starting in childhood, are linked to anemia, malnutrition, cognitive deficit, and in chronic cases of Opisth…
View article: Anticancer Potential of Valencia Peanut (Arachis hypogaea L.) Skin Extract against Cervical Cancer Cells In Vitro and in Nude Mouse Xenograft Models
Anticancer Potential of Valencia Peanut (Arachis hypogaea L.) Skin Extract against Cervical Cancer Cells In Vitro and in Nude Mouse Xenograft Models Open
This study investigated the impact of Valencia KK4-type peanut skin ethanolic extract (KK4-PSE) combined with cisplatin or 5-fluorouracil (5-FU) on HeLa cells in vitro and in xenograft models. At exposure times of 24, 48 and 72 h, KK4-PSE …
View article: Anticancer Activities of Peanut (Arachis hypogaea L.) Testa Extract in Combination With Cisplatin and 5-Fluorouracil Against Cholangiocarcinoma Cells In Vitro and in Mouse Xenograft Models
Anticancer Activities of Peanut (Arachis hypogaea L.) Testa Extract in Combination With Cisplatin and 5-Fluorouracil Against Cholangiocarcinoma Cells In Vitro and in Mouse Xenograft Models Open
Cholangiocarcinoma is an aggressive cancer with limited treatment options. Current therapies, such as cisplatin and 5-fluorouracil (5-FU), often cause side effects and drug resistance. This study investigated a potential new approach by co…
View article: Anticancer Potential of Valencia Peanut (<em>Arachis hypogaea </em>L.) Skin Extract against Cervical Cancer Cells In Vitro and in Nude Mouse Xenograft Models
Anticancer Potential of Valencia Peanut (<em>Arachis hypogaea </em>L.) Skin Extract against Cervical Cancer Cells In Vitro and in Nude Mouse Xenograft Models Open
This study aimed at investigating the effects of Valencia KK4-type peanut skin ethanolic extract (KK4-PSE) in combination with cisplatin or 5-fluorouracil (5-FU) against HeLa cells in vitro and in xenograft models. MTT assay showed that KK…
View article: Prevalence estimates of Opisthorchis viverrini and Clonorchis sinensis infection in the Greater Mekong subregion: a systematic review and meta-analysis
Prevalence estimates of Opisthorchis viverrini and Clonorchis sinensis infection in the Greater Mekong subregion: a systematic review and meta-analysis Open
View article: Towards an actionable One Health approach
Towards an actionable One Health approach Open
Background Despite the increasing focus on strengthening One Health capacity building on global level, challenges remain in devising and implementing real-world interventions particularly in the Asia-Pacific region. Recognizing these gaps,…
View article: Natural variables separate the endemic areas of Clonorchis sinensis and Opisthorchis viverrini along a continuous, straight zone in Southeast Asia
Natural variables separate the endemic areas of Clonorchis sinensis and Opisthorchis viverrini along a continuous, straight zone in Southeast Asia Open
View article: The importance of estimating the burden of disease from foodborne transmission of Trypanosoma cruzi
The importance of estimating the burden of disease from foodborne transmission of Trypanosoma cruzi Open
Chagas disease (ChD), caused by infection with the flagellated protozoan, Trypanosoma cruzi , has a complicated transmission cycle with many infection routes. These include vector-borne (via the triatomine (reduviid bug) vector defecating …
View article: Feline leptospirosis prevalence worldwide: A systematic review and meta-analysis of diagnostic approaches
Feline leptospirosis prevalence worldwide: A systematic review and meta-analysis of diagnostic approaches Open
Background and Aim: Leptospirosis in felids (domestic and wild cats) presents an ongoing challenge in our understanding. Numerous studies have reported the detection of Leptospira spp. in these feline populations, highlighting their potent…
View article: Extremely High Prevalence of Clonorchis Sinensis in Human and Unusually Low Infected Rate in Intermediate Hosts in Minority Area in Northern Guangxi, China
Extremely High Prevalence of Clonorchis Sinensis in Human and Unusually Low Infected Rate in Intermediate Hosts in Minority Area in Northern Guangxi, China Open
View article: Immunomics-Guided Biomarker Discovery for Opisthorchiasis and Opisthorchiasis-Associated Cholangiocarcinoma
Immunomics-Guided Biomarker Discovery for Opisthorchiasis and Opisthorchiasis-Associated Cholangiocarcinoma Open
View article: Anticancer Activities of Peanut (<i>Arachis hypogaea</i> L.) Testa Extract in Combination With Cisplatin and 5‐Fluorouracil Against Cholangiocarcinoma Cells <i>In Vitro</i> and in Mouse Xenograft Models
Anticancer Activities of Peanut (<i>Arachis hypogaea</i> L.) Testa Extract in Combination With Cisplatin and 5‐Fluorouracil Against Cholangiocarcinoma Cells <i>In Vitro</i> and in Mouse Xenograft Models Open
Cholangiocarcinoma (CCA) is a very aggressive cancer and CCA treatments with cisplatin and 5‐fluorouracil (5‐FU) often cause side effects and drug resistance. This study aimed to investigate the combined effects of Valencia KK4‐type peanut…