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View article: Large-scale epidemiology of opisthorchiasis in 21 provinces in Thailand based on diagnosis by fecal egg examination and urine antigen assay and analysis of risk factors for infection
Large-scale epidemiology of opisthorchiasis in 21 provinces in Thailand based on diagnosis by fecal egg examination and urine antigen assay and analysis of risk factors for infection Open
Introduction Infection with the carcinogenic fish-borne trematode Opisthorchis viverrini, known as opisthorchiasis, is a major cause of biliary cancer (cholangiocarcinoma). Despite decades of disease prevention and control in Thailand, the…
View article: Effect of the Chronic Kidney Disease—Peritoneal Dialysis (CKD-PD) App on Improvement of Overhydration Treatment in Patients on Peritoneal Dialysis: Randomized Controlled Trial
Effect of the Chronic Kidney Disease—Peritoneal Dialysis (CKD-PD) App on Improvement of Overhydration Treatment in Patients on Peritoneal Dialysis: Randomized Controlled Trial Open
Background Overhydration is associated with increased morbidity and mortality in patients on peritoneal dialysis (PD). Early detection of overhydration is possible by monitoring hydration metrics, but the critical gap for treatment is obta…
View article: Effect of Time Interval and Frequency of Hospitalization Because of Fluid Overload on Survival in Peritoneal Dialysis: Thailand Experience
Effect of Time Interval and Frequency of Hospitalization Because of Fluid Overload on Survival in Peritoneal Dialysis: Thailand Experience Open
Key Points High mortality was found in patients on peritoneal dialysis who were hospitalized early or frequently because of fluid overload. Interval time and frequency of hospitalization because of fluid overload are clinical indicators fo…
View article: Improvement of survival outcomes of cholangiocarcinoma by ultrasonography surveillance: Multicenter retrospective cohorts
Improvement of survival outcomes of cholangiocarcinoma by ultrasonography surveillance: Multicenter retrospective cohorts Open
US is an effective tool for detecting early stage CCA leading to improve clinical outcome of CCA patients. Practically, US should be considered as a first tool for screening CCA in risk populations.
View article: The Long-Term, Real-World Effects of Oxybutynin on Pressure Reservoir Function in the Neurogenic Bladder after Spinal Cord Injury: A Retrospective Cohort Study
The Long-Term, Real-World Effects of Oxybutynin on Pressure Reservoir Function in the Neurogenic Bladder after Spinal Cord Injury: A Retrospective Cohort Study Open
Background/Objectives: Data on the long-term effects of oxybutynin in patients with neurogenic bladder (NGB) due to spinal cord injury (SCI) are limited. This study aimed to evaluate the long-term effects of oxybutynin and the combination …
View article: Short‑term effects of oxybutynin dosage in individuals with neurogenic bladder following spinal cord injury: A retrospective cohort study
Short‑term effects of oxybutynin dosage in individuals with neurogenic bladder following spinal cord injury: A retrospective cohort study Open
The aim of the present study was to determine the relationship between dose of oxybutynin and reduction in detrusor pressure in individuals with neurogenic bladder (NGB) secondary to spinal cord injury (SCI). The hospital-based data were e…
View article: The Survival and Associated Factors for Patients on Peritoneal Dialysis With History of Admission From Volume Overload
The Survival and Associated Factors for Patients on Peritoneal Dialysis With History of Admission From Volume Overload Open
Introduction: Patients with peritoneal dialysis (PD) who develop volume overload (VO) have high risks of dropout from death or advancement to hemodialysis. We aimed to determine the mortality rates, associated factors, and patient survival…
View article: Improvement of Survival Outcomes of Cholangiocarcinoma by Ultrasonography Surveillance: Multicenter Retrospective Cohorts
Improvement of Survival Outcomes of Cholangiocarcinoma by Ultrasonography Surveillance: Multicenter Retrospective Cohorts Open
Introduction Most cholangiocarcinoma (CCA) patients present with late stage of disease because of the difficulty to diagnosis at an early stage, resulting in poor survival of CCA patients. The Cholangiocarcinoma Screening and Care Program …
View article: Association of Cholangiocarcinoma among People with Periductal Fibrosis
Association of Cholangiocarcinoma among People with Periductal Fibrosis Open
Our findings demonstrate a significant association between fibrosis of the segmental and main bile ducts (PDF2 and PDF3) and CCA, with the strongest association observed in participants with PDF3. Hepatobiliary US screening could serve as …
View article: Data sharing implementation in top 10 ophthalmology journals in 2021
Data sharing implementation in top 10 ophthalmology journals in 2021 Open
Background/Aims Deidentified individual participant data (IPD) sharing has been implemented in the International Committee of Medical Journal Editors journals since 2017. However, there were some published clinical trials that did not foll…
View article: Prevalence of Suspected Cholangiocarcinoma Based on Ultrasonography Screening and its Associated Factors in Northeastern Thailand
Prevalence of Suspected Cholangiocarcinoma Based on Ultrasonography Screening and its Associated Factors in Northeastern Thailand Open
Background Ultrasonography of the liver allows detection of liver mass and bile duct dilatation which are findings of suspected Cholangiocarcinoma so that early stage Cholangiocarcinoma can be detected.
Objective To estimate the prevalen…
View article: Optimization of the Chronic Kidney Disease–Peritoneal Dialysis App to Improve Care for Patients on Peritoneal Dialysis in Northeast Thailand: User-Centered Design Study
Optimization of the Chronic Kidney Disease–Peritoneal Dialysis App to Improve Care for Patients on Peritoneal Dialysis in Northeast Thailand: User-Centered Design Study Open
Background The prevalence of peritoneal dialysis (PD) in Thailand is increasing rapidly in part because of Thailand’s Peritoneal Dialysis First policy. PD is a home-based renal replacement therapy in which patients with chronic kidney dise…
View article: Association between the Number of Repeated Praziquantel Treatments and Kidney Parenchymal Change in Northeast Thailand
Association between the Number of Repeated Praziquantel Treatments and Kidney Parenchymal Change in Northeast Thailand Open
The number of repeated PZQ treatments is statistically significantly related to KPC. This relationship could be included in health messaging for those who continue eating uncooked fish with an understanding that the OV infection can easily…
View article: Optimization of the Chronic Kidney Disease–Peritoneal Dialysis App to Improve Care for Patients on Peritoneal Dialysis in Northeast Thailand: User-Centered Design Study (Preprint)
Optimization of the Chronic Kidney Disease–Peritoneal Dialysis App to Improve Care for Patients on Peritoneal Dialysis in Northeast Thailand: User-Centered Design Study (Preprint) Open
BACKGROUND The prevalence of peritoneal dialysis (PD) in Thailand is increasing rapidly in part because of Thailand’s Peritoneal Dialysis First policy. PD is a home-based renal replacement therapy in which patients with chronic kidney dis…
View article: High Levels of Serum IgG for Opisthorchis viverrini and CD44 Expression Predict Worse Prognosis for Cholangiocarcinoma Patients after Curative Resection
High Levels of Serum IgG for Opisthorchis viverrini and CD44 Expression Predict Worse Prognosis for Cholangiocarcinoma Patients after Curative Resection Open
A high level of OV IgG as well as a high level of CSC markers resulted in an aggressive CCA. OV IgG level together with CSC markers can be used as the prognostic markers for CCA patients' survival. The study of the CD44 pathway is promisin…
View article: Rate of Hypokalemia and Risk Factors in Patients on Peritoneal Dialysis Under PD First Policy
Rate of Hypokalemia and Risk Factors in Patients on Peritoneal Dialysis Under PD First Policy Open
Background: Hypokalemia is common among peritoneal dialysis (PD) patients. The incidence rate ofhypokalemia and risk factors were investigated.Material and Method: A retrospective cohort, enrolled 1,044 incident PD patients under the Unive…
View article: Survival after Surgery among Patients with Cholangiocarcinoma in Northeast Thailand According to Anatomical and Morphological Classification
Survival after Surgery among Patients with Cholangiocarcinoma in Northeast Thailand According to Anatomical and Morphological Classification Open
Background: Cholangiocarcinoma (CCA) has been categorized based on tumor location as intrahepatic (ICCA), perihilar (PCCA) or distal (DCCA), and based on the morphology of the tumor of the bile duct as mass forming (MF), periductal infiltr…
View article: <p>Serum IgG as a Marker for <em>Opisthorchis viverrini</em>-Associated Cholangiocarcinoma Correlated with HER2 Overexpression</p>
Serum IgG as a Marker for <em>Opisthorchis viverrini</em>-Associated Cholangiocarcinoma Correlated with HER2 Overexpression Open
We found a high prevalence of serum IgG for OV-positive CCA patients and a correlation with overexpression of HER2. Moreover, IgG for OV and HER2 expression indicated poor survival of CCA. Therefore, future clinical studies for anti-HER2 t…
View article: Serum IgG as a Marker for Opisthorchis viverrini-Associated Cholangiocarcinoma Correlated with HER2 Overexpression
Serum IgG as a Marker for Opisthorchis viverrini-Associated Cholangiocarcinoma Correlated with HER2 Overexpression Open
Attapol Titapun,1,2 Anchalee Techasen,2,3 Prakasit Sa-Ngiamwibool,2,4 Paiboon Sithithaworn,2,5 Vor Luvira,1,2 Tharatip Srisuk,1,2 Apiwat Jareanrat,1,2 Hasaya Dokduang,2,6 Watcharin Loilome,2,6 Bandit Thinkhamrop,2,7 Narong Khuntikeo1,2 1De…
View article: Comparison of All-cause Mortality and Technique Failure Between Early-late and Very Late Start Peritoneal Dialysis: A Retrospective Cohort Study
Comparison of All-cause Mortality and Technique Failure Between Early-late and Very Late Start Peritoneal Dialysis: A Retrospective Cohort Study Open
Background: Glomerular filtration rate (GFR) is the gold standard for the detection and monitoring ofchronic kidney disease (CKD). Controversy is remaining in the timing of peritoneal dialysis (PD).Objective: This study compared all-cause …
View article: Major Adverse Cardiovascular Events in Patients Starting Peritoneal Dialysis Based on the CKD-EPI Versus Thai eGFR Equation: A Retrospective Cohort Study
Major Adverse Cardiovascular Events in Patients Starting Peritoneal Dialysis Based on the CKD-EPI Versus Thai eGFR Equation: A Retrospective Cohort Study Open
Background: Major adverse cardiovascular events (MACE) are the leading cause of deathin chronic kidneydisease (CKD) patients. The relationship between the initiation of peritoneal dialysis (PD) and MACE isunclear.Objective: This study comp…
View article: Spatial analysis of hepatobiliary abnormalities in a population at high-risk of cholangiocarcinoma in Thailand
Spatial analysis of hepatobiliary abnormalities in a population at high-risk of cholangiocarcinoma in Thailand Open
Cholangiocarcinoma ( CCA) is a serious health challenge with low survival prognosis. The liver fluke, Opisthorchis viverrini , plays a role in the aetiology of CCA, through hepatobiliary abnormalities: liver mass (LM), bile duct dilation, …
View article: CKDNET, a quality improvement project for prevention and reduction of chronic kidney disease in the Northeast Thailand
CKDNET, a quality improvement project for prevention and reduction of chronic kidney disease in the Northeast Thailand Open
Background The incidence of chronic kidney disease (CKD) is high in the Northeast Thailand compared to other parts of the country. Therefore, a broad program applying all levels of care is inevitable. This paper describes the results of th…