Baode Chen
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An Integrated Afterglow and MRI Probe for In Vivo Imaging of ATP in Tumor Metabolism Open
Adenosine triphosphate (ATP) is a central mediator of cancer cell metabolism and signaling, driving processes such as proliferation, invasion, metastasis, and therapeutic resistance. Current ATP imaging modalities‐including fluorescence, c…
Ultrabright difuranfluoreno-dithiophen polymers for enhanced afterglow imaging of atherosclerotic plaques Open
Cardiovascular diseases, including stroke driven by atherosclerosis, remain a leading global health concern. Current diagnostic imaging modalities such as magnetic resonance imaging fail to characterize oxidative stress within atherosclero…
Assessment of impact of left ventricular flow state on myocardial blood flow using positron emission tomography and echocardiography Open
Background The relationship between left ventricular (LV) mass and myocardial blood flow (MBF) has been recognized as an important physiological measure of myocardial perfusion to match global metabolic demand. However, there is little inf…
Simultaneous In Vivo Imaging of Neutrophil Elastase and Oxidative Stress in Atherosclerotic Plaques Using a Unimolecular Photoacoustic Probe Open
Atherosclerosis, a major global health concern with high morbidity and mortality rates, involves complex interactions of chronic inflammation, oxidative stress, and proteolytic enzymes. Conventional imaging methods struggle to capture the …
Simultaneous In Vivo Imaging of Neutrophil Elastase and Oxidative Stress in Atherosclerotic Plaques Using a Unimolecular Photoacoustic Probe Open
Atherosclerosis, a major global health concern with high morbidity and mortality rates, involves complex interactions of chronic inflammation, oxidative stress, and proteolytic enzymes. Conventional imaging methods struggle to capture the …
View article: Improving Visibility Forecasting during Haze-fog Processes in Shanghai and Eastern China: the Significance of Aerosol and Hydrometeor
Improving Visibility Forecasting during Haze-fog Processes in Shanghai and Eastern China: the Significance of Aerosol and Hydrometeor Open
Aerosols and droplets are the main factors of visibility reduction by scattering and absorbing light. For visibility predictions in operational NWP models, hydrometeors are often considered to be the dominant factor in the total extinction…
Elevated D-Dimer levels correlate with the development of hepatorenal syndrome and a poor outcome in patients with cirrhosis Open
Whether hemostatic status was correlated with the diverse types of acute kidney injury in cirrhotic patients is unclear. The present study aimed to investigate the relationship between hemostatic markers and the diverse types of acute kidn…
The Love-Hate Relationship Between TGF-β Signaling and the Immune System During Development and Tumorigenesis Open
Since TGF-β was recognized as an essential secreted cytokine in embryogenesis and adult tissue homeostasis a decade ago, our knowledge of the role of TGF-β in mammalian development and disease, particularly cancer, has constantly been upda…
View article: Evaluation and Comparison of Two Deep Convection Parameterization Schemes at Convection-Permitting Resolution
Evaluation and Comparison of Two Deep Convection Parameterization Schemes at Convection-Permitting Resolution Open
Coarse-grained results from a large-eddy simulation (LES) using the Weather Research and Forecasting (WRF) Model were compared in this study with the WRF simulations at a typical convection-permitting horizontal grid spacing of 3 km for an…
Serum free light chain is associated with histological activity and cirrhosis in patients with chronic hepatitis B Open
Our work revealed that serum free light chains were associated with histological activity and cirrhosis in chronic hepatitis B, which could play a crucial role in the immunopathogenesis of HBV-associated cirrhosis. In addition, free kappa …
Using Cell Type–Specific Genes to Identify Cell-Type Transitions Between Different in vitro Culture Conditions Open
In vitro differentiation or expansion of stem and progenitor cells under chemical stimulation or genetic manipulation is used for understanding the molecular mechanisms of cell differentiation and self-renewal. However, concerns around the…
Improving numerical simulation of typhoon LEKIMA(2019) through assimilating ATMS radiance data Open
Lacking of high-resolution observations over oceans is one of the major problems for the numerical simulation of the tropical cyclones (TC), especially for the tropical cyclone inner-core structures simulation. Satellite observations plays…
Evaluation of scale-aware convection schemes at the kilometer-scale resolution Open
Numerical weather predictions (NWP) models are increasingly run using kilometer-scale horizontal grid spacing at which convection is partially resolved and the use of a subgrid convection parameterization scheme is still required. Traditio…
A comparison study of aerosol impacts on idealized supercell between two bulk microphysics parameterizations Open
Considering aerosol effects via microphysics parameterization is an imperative work in high-resolution numerical weather prediction. This paper uses two bulk microphysics parameterizations, Aerosol-Aware Thompson and CLR schemes, with the …
A Three-Dimensional Scale-Adaptive Turbulent Kinetic Energy Scheme in the WRF-ARW Model Open
A new three-dimensional (3D) turbulent kinetic energy (TKE) subgrid mixing scheme is developed using the Advanced Research version of the Weather Research and Forecasting (WRF) Model (WRF-ARW) to address the gray-zone problem in the parame…
Evaluation of Sysmex XN-1000 hematology analyzer for cell count and screening of malignant cells of serous cavity effusion Open
Over the years, with the advancement in hematology analyzer technology, the use of fluid analysis method has seen a drastic increase in clinical examinations. Cell counting and classification in independent body fluid analysis method are c…
Contribution of urbanization to the increase of extreme heat events in an urban agglomeration in east China Open
The urban agglomeration of Yangtze River Delta (YRD) is emblematic of China's rapid urbanization during the past decades. Based on homogenized daily maximum and minimum temperature data, the contributions of urbanization to trends of summe…