Bin Wu
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View article: Neuronal Endothelin a Receptor Mediates Experimental and Clinical Vascular Pain through an Endothelial‐Neural Axis
Neuronal Endothelin a Receptor Mediates Experimental and Clinical Vascular Pain through an Endothelial‐Neural Axis Open
Vascular dysfunction causes vascular pain (VP), the most common clinical manifestation of prevalent vascular diseases, while the mechanisms remain elusive. Mouse models are developed by mimicking peripheral vascular diseases and combining …
View article: CCDC 2371624: Experimental Crystal Structure Determination
CCDC 2371624: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Zero-carbon emission molecular energy technology and experiments
Zero-carbon emission molecular energy technology and experiments Open
This article introduces the concept of a "nanoscale one-way valve" and its underlying principles, pointing out that osmosis is a natural manifestation of the nanoscale one-way valve effect, the energy basis is the molecular thermal motion.…
View article: Targeting Neuronal Cuproptosis and Neuroinflammation with Biomimetic Nanoparticle for the Therapy of Radiotherapy-Induced Brain Injury
Targeting Neuronal Cuproptosis and Neuroinflammation with Biomimetic Nanoparticle for the Therapy of Radiotherapy-Induced Brain Injury Open
View article: Principle, method and experimental verification of Zero-Carbon emission reverse osmosis clean energy technology
Principle, method and experimental verification of Zero-Carbon emission reverse osmosis clean energy technology Open
This article introduces the concept of a "nanoscale one-way valve" and its underlying principles, pointing out that permeation is a natural manifestation of the nanoscale one-way valve effect,the energy basis is the molecular thermal motio…
View article: Effects of aripiprazole on prolactin levels and differences in effectiveness in patients with schizophrenia: a post-hoc analysis of the real-world data of a multicenter study
Effects of aripiprazole on prolactin levels and differences in effectiveness in patients with schizophrenia: a post-hoc analysis of the real-world data of a multicenter study Open
Objectives To investigate the effect of aripiprazole on prolactin levels in patients with schizophrenia and analyze whether varying baseline prolactin levels affect the effectiveness and safety of aripiprazole, in a real-life diagnostic an…
View article: Randomized, double-blind, placebo-controlled trial of aripiprazole oral solution in children and adolescents with Tourette’s disorder
Randomized, double-blind, placebo-controlled trial of aripiprazole oral solution in children and adolescents with Tourette’s disorder Open
Background Aripiprazole is the most frequently recommended antipsychotic for the treatment of tics in children and adolescents with Tourette’s disorder (TD). However, to date, a randomized controlled trial for aripiprazole oral solution ha…
View article: Changes in amino acids, catechins and alkaloids during the storage of oolong tea and their relationship with antibacterial effect
Changes in amino acids, catechins and alkaloids during the storage of oolong tea and their relationship with antibacterial effect Open
The storage process has a significant impact on tea quality. Few is known about effect of storage on quality of oolong tea. This study aimed to assess the effect of different storage times on the key chemical components of oolong tea by me…
View article: Maternal immune activation induces sex-dependent behavioral differences in a rat model of schizophrenia
Maternal immune activation induces sex-dependent behavioral differences in a rat model of schizophrenia Open
Background Maternal immune activation (MIA) is a mature means to construct a schizophrenia model. However, some preclinical studies have reported that a MIA-induced schizophrenia model seemed to have gender heterogeneity in behavioral phen…
View article: Amifostine ameliorates bleomycin-induced murine pulmonary fibrosis via NAD+/SIRT1/AMPK pathway-mediated effects on mitochondrial function and cellular metabolism
Amifostine ameliorates bleomycin-induced murine pulmonary fibrosis via NAD+/SIRT1/AMPK pathway-mediated effects on mitochondrial function and cellular metabolism Open
Background Idiopathic pulmonary fibrosis (IPF) is a devastating chronic lung disease characterized by irreversible scarring of the lung parenchyma. Despite various interventions aimed at mitigating several different molecular aspects of th…
View article: CCDC 2281024: Experimental Crystal Structure Determination
CCDC 2281024: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2261847: Experimental Crystal Structure Determination
CCDC 2261847: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2283919: Experimental Crystal Structure Determination
CCDC 2283919: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: A phase 3, multicenter, double-blind, randomized, placebo-controlled clinical trial to verify the efficacy and safety of ansofaxine (LY03005) for major depressive disorder
A phase 3, multicenter, double-blind, randomized, placebo-controlled clinical trial to verify the efficacy and safety of ansofaxine (LY03005) for major depressive disorder Open
Major depressive disorder (MDD) is the most prevalent form of depression and is becoming a great challenge for public health and medical practice. Although first-line antidepressants offer therapeutic benefits, about 35% of depressed patie…
View article: Aripiprazole in the treatment of acute episode of schizophrenia: a real-world study in China
Aripiprazole in the treatment of acute episode of schizophrenia: a real-world study in China Open
To the Editor: Schizophrenia is a progressive, debilitating disease.[1] Safe and effective treatment performed during the acute phase is the first step to improve prognosis, and it is critically important. Aripiprazole is known as a dopami…
View article: Exploration and Practice of Health Communication in Hospital Under the Background of the Healthy China Initiative
Exploration and Practice of Health Communication in Hospital Under the Background of the Healthy China Initiative Open
Along with the increasing quality of human life, people pay more attention to healthcare. Public health and one's health have become daily issues. As a branch of communication, more and more scholars pay attention to health communication s…
View article: CSD 2244442: Experimental Crystal Structure Determination
CSD 2244442: Experimental Crystal Structure Determination Open
An entry from the Inorganic Crystal Structure Database, the world’s repository for inorganic crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely availabl…
View article: CCDC 2184322: Experimental Crystal Structure Determination
CCDC 2184322: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: From big data to higher bureaucratic capacity: Poverty alleviation in China
From big data to higher bureaucratic capacity: Poverty alleviation in China Open
This study explores how big data technologies can create an “information commons” shared by all policy stakeholders to alleviate the corruption and information asymmetries long endemic to poverty alleviation programs. We argue that the inf…
View article: The design and synthesis of benzylpiperazine-based edaravone derivatives and their neuroprotective activities
The design and synthesis of benzylpiperazine-based edaravone derivatives and their neuroprotective activities Open
New edaravone derivatives containing a benzylpiperazine moiety are designed and synthesized. The structures are characterized by 1 H NMR, 13 C NMR, and high-resolution mass spectrometry. The potential neuroprotective activities of the targ…
View article: CCDC 2080761: Experimental Crystal Structure Determination
CCDC 2080761: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2131880: Experimental Crystal Structure Determination
CCDC 2131880: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2141725: Experimental Crystal Structure Determination
CCDC 2141725: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: DNA methylation in polycystic ovary syndrome: Emerging evidence and challenges
DNA methylation in polycystic ovary syndrome: Emerging evidence and challenges Open
Polycystic ovary syndrome (PCOS) is a disease related to reproductive endocrine abnormalities in women of reproductive age, often accompanied by metabolic diseases such as hyperandrogenemia, insulin resistance and dyslipidemia. However, th…
View article: Effectiveness and safety of blonanserin for improving social and cognitive functions in patients with first-episode schizophrenia: a study protocol for a prospective, multicentre, single-arm clinical trial
Effectiveness and safety of blonanserin for improving social and cognitive functions in patients with first-episode schizophrenia: a study protocol for a prospective, multicentre, single-arm clinical trial Open
Introduction Both the pharmacological characteristics of blonanserin and its related small sample size studies suggest that blonanserin could alleviate social and cognitive dysfunctions in patients with schizophrenia. However, no large sam…
View article: CCDC 2061060: Experimental Crystal Structure Determination
CCDC 2061060: Experimental Crystal Structure Determination Open
View article: CCDC 1966233: Experimental Crystal Structure Determination
CCDC 1966233: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1828774: Experimental Crystal Structure Determination
CCDC 1828774: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1810959: Experimental Crystal Structure Determination
CCDC 1810959: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1843963: Experimental Crystal Structure Determination
CCDC 1843963: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …