Barbara J. Smith
YOU?
Author Swipe
View article: Peroxisomes regulate virulence and cell density sensing in <i>Cryptococcus neoformans</i>
Peroxisomes regulate virulence and cell density sensing in <i>Cryptococcus neoformans</i> Open
Cryptococcus neoformans , a ubiquitous environmental fungus that causes cryptococcosis, survives in diverse environments including human hosts due to metabolic flexibility. Consequently, identifying how C. neoformans connects diverse metab…
View article: Application Variables that Affect Efficacy of Disinfestants Sprayed on Different Substrate Materials to Control <i>Colletotrichum siamense</i>
Application Variables that Affect Efficacy of Disinfestants Sprayed on Different Substrate Materials to Control <i>Colletotrichum siamense</i> Open
Disinfestants are an important sanitation tool used to eliminate plant pathogens. Disinfestant product labels, as well as university and company literature, provide instructions and guidance for the proper usage of disinfestants, yet recen…
View article: Exploring the frequency, types, parental experiences, and sociodemographic characteristics of squeeze pouch use in infants and children aged 0–18 years: a scoping review of the literature
Exploring the frequency, types, parental experiences, and sociodemographic characteristics of squeeze pouch use in infants and children aged 0–18 years: a scoping review of the literature Open
Establishing early healthy eating behaviours in the complementary feeding period through to adolescence is fundamental as it can affect the health trajectory of an infant’s life into adulthood and impact lifelong eating patterns (1) . Cons…
View article: Establishment of Southern Highbush Blueberry Cultivars and Suppression of Phytophthora Root Rot Using Cover Crop and Soil Amendment Treatments
Establishment of Southern Highbush Blueberry Cultivars and Suppression of Phytophthora Root Rot Using Cover Crop and Soil Amendment Treatments Open
Phytophthora root rot is a major disease of blueberry that relies on cultural practices, including soil amendments, for disease management. We evaluated the effect of three cover crops on the establishment and growth of southern highbush b…
View article: The loss of both pUL16 and pUL21 in HSV-1-infected cells alters capsid–tegument composition, nuclear membrane architecture, cytoplasmic maturation and cell-to-cell spread
The loss of both pUL16 and pUL21 in HSV-1-infected cells alters capsid–tegument composition, nuclear membrane architecture, cytoplasmic maturation and cell-to-cell spread Open
Previously, we had developed synthetic genomics methods to assemble an infectious clone of herpes simplex virus type-1 (HSV-1) strain KOS. To do this, the genome was assembled from 11 separate cloned fragments in yeast using transformation…
View article: The loss of both pUL16 and pUL21 in HSV-1 infected cells abolishes cytoplasmic envelopment
The loss of both pUL16 and pUL21 in HSV-1 infected cells abolishes cytoplasmic envelopment Open
Previously, we had developed synthetic genomics methods to assemble an infectious clone of herpes simplex virus type-1 (HSV-1). To do this, the genome was assembled from 11 separate cloned fragments in yeast using transformation associated…
View article: UVC (254 nm) and Far UVC (222 nm) Irradiation Affects In Vitro Growth of <i>Colletotrichum</i> sp. Isolates and Their Infection of Detached Strawberry Leaves
UVC (254 nm) and Far UVC (222 nm) Irradiation Affects In Vitro Growth of <i>Colletotrichum</i> sp. Isolates and Their Infection of Detached Strawberry Leaves Open
Conventional ultraviolet C at 254 nm (UVC) and Far UVC at 222 nm (Far UVC) were evaluated as alternatives to fungicides for disease control. Conidia of 13 isolates of strawberry anthracnose pathogens (five Colletotrichum species in two com…
View article: Environmental Influences on the Drying Rate of Spray-Applied Disinfestants from Horticultural Production Surfaces
Environmental Influences on the Drying Rate of Spray-Applied Disinfestants from Horticultural Production Surfaces Open
Drying rates of disinfestants commonly applied to horticultural plant production surfaces were evaluated under cool to hot weather and under laboratory conditions to characterize the range of drying times and how this relates to contact ti…
View article: Nelfinavir inhibition of Kaposi’s sarcoma-associated herpesvirus protein expression and capsid assembly
Nelfinavir inhibition of Kaposi’s sarcoma-associated herpesvirus protein expression and capsid assembly Open
Background Antiviral therapies that target herpesviruses are clinically important. Nelfinavir is a protease inhibitor that targets the human immunodeficiency virus (HIV) aspartyl protease. Previous studies demonstrated that this drug could…
View article: Nelfinavir Inhibition of Kaposi’s sarcoma-associated herpesvirus protein expression and capsid assembly
Nelfinavir Inhibition of Kaposi’s sarcoma-associated herpesvirus protein expression and capsid assembly Open
Background Antiviral therapies that target herpesviruses are clinically important. Nelfinavir is a protease inhibitor that targets the human immunodeficiency virus (HIV) infections aspartyl protease. Previous studies demonstrated that this…
View article: Environmental Influences on the Evaporation Rate of Horticultural Disinfestants
Environmental Influences on the Evaporation Rate of Horticultural Disinfestants Open
The evaporation rate of disinfestants when sprayed on production surfaces is expected to vary under different weather conditions, but it is unknown how that affects efficacy. This study was an initial investigation into how the evaporation…
View article: Interleukin-6 Drives Mitochondrial Dysregulation and Accelerates Physical Decline: Insights From an Inducible Humanized IL-6 Knock-In Mouse Model
Interleukin-6 Drives Mitochondrial Dysregulation and Accelerates Physical Decline: Insights From an Inducible Humanized IL-6 Knock-In Mouse Model Open
Chronic activation of inflammatory pathways (CI) and mitochondrial dysfunction are independently linked to age-related functional decline and early mortality. Interleukin 6 (IL-6) is among the most consistently elevated chronic activation …
View article: Intensity of Supplemental Greenhouse Lighting Affects Strawberry Plant Growth, Anthracnose Infection Response, and Colletotrichum Pathogen Development in Culture
Intensity of Supplemental Greenhouse Lighting Affects Strawberry Plant Growth, Anthracnose Infection Response, and Colletotrichum Pathogen Development in Culture Open
The effect of supplemental lighting on strawberry growth and anthracnose disease response of three strawberry ( Fragaria × ananassa ) cultivars was evaluated in two greenhouse trials, and the effect on strawberry anthracnose pathogens ( Co…
View article: Melanization of Candida auris Is Associated with Alteration of Extracellular pH
Melanization of Candida auris Is Associated with Alteration of Extracellular pH Open
Candida auris is a recently emerged global fungal pathogen, which causes life-threatening infections, often in healthcare settings. C. auris infections are worrisome because the fungus is often resistant to multiple antifungal drug classes…
View article: Pharmacokinetics and biodistribution of extracellular vesicles administered intravenously and intranasally to <i>Macaca nemestrina</i>
Pharmacokinetics and biodistribution of extracellular vesicles administered intravenously and intranasally to <i>Macaca nemestrina</i> Open
Extracellular vesicles (EVs) have potential in disease treatment since they can be loaded with therapeutic molecules and engineered for retention by specific tissues. However, questions remain on optimal dosing, administration and pharmaco…
View article: Melanization of<i>Candida auris</i>is Associated with Alteration of Extracellular pH
Melanization of<i>Candida auris</i>is Associated with Alteration of Extracellular pH Open
Candida auris is a recently emerged global fungal pathogen, which causes life-threatening infections, often in healthcare settings. C. auris infections are worrisome because the fungus is often resistant to multiple antifungal drug classes…
View article: Effect of Light-emitting Diodes, Ultraviolet-B, and Fluorescent Supplemental Greenhouse Lights on Strawberry Plant Growth and Response to Infection by the Anthracnose Pathogen Colletotrichum gloeosporioides
Effect of Light-emitting Diodes, Ultraviolet-B, and Fluorescent Supplemental Greenhouse Lights on Strawberry Plant Growth and Response to Infection by the Anthracnose Pathogen Colletotrichum gloeosporioides Open
Supplemental lighting is frequently used to extend daylength for strawberries ( Fragaria × ananassa ) grown in greenhouses and high tunnels; however, information is limited on the effect of these lights on disease development. We evaluated…
View article: A bacterial extracellular vesicle‐based intranasal vaccine against SARS‐CoV‐2 protects against disease and elicits neutralizing antibodies to wild‐type and Delta variants
A bacterial extracellular vesicle‐based intranasal vaccine against SARS‐CoV‐2 protects against disease and elicits neutralizing antibodies to wild‐type and Delta variants Open
Several vaccines have been introduced to combat the coronavirus infectious disease‐2019 (COVID‐19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Current SARS‐CoV‐2 vaccines include mRNA‐containing lipid …
View article: Nuclear DNA content and chromosome number determination in a Sahel medicinal plant, <i>Combretum micranthum</i> G. Don
Nuclear DNA content and chromosome number determination in a Sahel medicinal plant, <i>Combretum micranthum</i> G. Don Open
Combretum micranthum G. Don, also known as kinkéliba, is native to West Africa where the plant grows wild as a shrub, liana, or tree and is valued for its numerous attributes including health and nutritional benefits. Despite this, genetic…
View article: Determination of Genome Size and Chromosome Number of a Ziziphus Species (Z. mauritiana Lam.) from Eastern Senegal
Determination of Genome Size and Chromosome Number of a Ziziphus Species (Z. mauritiana Lam.) from Eastern Senegal Open
Ziziphus mauritiana Lam. is a widespread shrub or tree of the Sahel region, where it grows wild and is used for various purposes, including nutrition, medicine, and firewood. Current domestication programs focus on using the local species …
View article: Additional Nitrogen Application Reduced White Drupelet Disorder in ‘Sweetie Pie’ Blackberry
Additional Nitrogen Application Reduced White Drupelet Disorder in ‘Sweetie Pie’ Blackberry Open
White drupelet disorder (WDD) in blackberry ( Rubus subgenus Rubus ) is an abiotic condition resulting from a cultivar and environment interaction. Although high temperatures and light intensities have been implicated, little is known why …
View article: Valsartan <scp>nano‐filaments</scp> alter mitochondrial energetics and promote faster healing in diabetic rat wounds
Valsartan <span>nano‐filaments</span> alter mitochondrial energetics and promote faster healing in diabetic rat wounds Open
Chronic wounds are a common and debilitating condition associated with aging populations that impact more than 6.5 million patients in the United States. We have previously demonstrated the efficacy of daily topical 1% valsartan in treatin…
View article: Micropropagation of Hibiscus moscheutos L. ‘Luna White’: effect of growth regulators and explants on nuclear DNA content and ploidy stability of regenerants
Micropropagation of Hibiscus moscheutos L. ‘Luna White’: effect of growth regulators and explants on nuclear DNA content and ploidy stability of regenerants Open
Hibiscus moscheutos L., also known as hardy hibiscus, is valued for its medicinal and ornamental attributes. It is usually propagated via seeds or cuttings. The purpose of this investigation was to develop a dependable micropropagation for…
View article: Pharmacokinetics and biodistribution of extracellular vesicles administered intravenously and intranasally to <i>Macaca nemestrina</i>
Pharmacokinetics and biodistribution of extracellular vesicles administered intravenously and intranasally to <i>Macaca nemestrina</i> Open
Extracellular vesicles (EVs) have great potential as novel drug carriers for the treatment of various diseases. These lipid bilayer vesicles are naturally abundant in mammalian tissues and circulation, can be loaded with therapeutic small …
View article: A bacterial extracellular vesicle-based intranasal vaccine against SARS-CoV-2 protects against disease and elicits neutralizing antibodies to wild-type and Delta variants
A bacterial extracellular vesicle-based intranasal vaccine against SARS-CoV-2 protects against disease and elicits neutralizing antibodies to wild-type and Delta variants Open
Several vaccines have been introduced to combat the coronavirus infectious disease-2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Current SARS-CoV-2 vaccines include mRNA-containing lipid …
View article: Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single‐particle analysis platforms
Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single‐particle analysis platforms Open
We compared four orthogonal technologies for sizing, counting, and phenotyping of extracellular vesicles (EVs) and synthetic particles. The platforms were: single‐particle interferometric reflectance imaging sensing (SP‐IRIS) with fluoresc…
View article: Higher Renovation Pruning Height Improves Early Yields of ‘Woodard’ Rabbiteye Blueberry
Higher Renovation Pruning Height Improves Early Yields of ‘Woodard’ Rabbiteye Blueberry Open
Rabbiteye blueberry ( Vaccinium virgatum ) bushes are relatively easy to grow and commonplace across Mississippi; however, if not properly maintained, the bushes will decline over time. Eighteen, aged, low-productivity ‘Woodard’ rabbiteye …
View article: Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single-particle analysis platforms
Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single-particle analysis platforms Open
We compared four orthogonal technologies for sizing, counting, and phenotyping of extracellular vesicles (EVs) and synthetic particles. The platforms were: single-particle interferometric reflectance imaging sensing (SP-IRIS) with fluoresc…
View article: Genotyping Xylella fastidiosa in Rabbiteye blueberry in Louisiana, USA
Genotyping Xylella fastidiosa in Rabbiteye blueberry in Louisiana, USA Open
Rabbiteye blueberry ( Vaccinium ashei = V. virgatum ) comprises much of the blueberry acreage in the southeastern USA states of Louisiana and Mississippi. Three genotypes of X. fastidiosa were identified from rabbiteye blueberry in Louisia…