Barbara Pavlová
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View article: Preferences for virtual versus in-person mental and physical healthcare in Canada: a descriptive study from a cohort of youth and their parents enriched for severe mental illness
Preferences for virtual versus in-person mental and physical healthcare in Canada: a descriptive study from a cohort of youth and their parents enriched for severe mental illness Open
Background Virtual care may improve access to healthcare and may be well suited to digitally connected youth, but experts caution that privacy and technology barriers could perpetuate access inequities. Success of virtual care will depend …
View article: Transdiagnostic risk of mental disorders in offspring of affected parents: a meta‐analysis of family high‐risk and registry studies
Transdiagnostic risk of mental disorders in offspring of affected parents: a meta‐analysis of family high‐risk and registry studies Open
The offspring of parents with mental disorders are at increased risk for developing mental disorders themselves. The risk to offspring may extend transdiagnostically to disorders other than those present in the parents. The literature on t…
View article: Depressive symptoms in youth before and during the COVID-19 pandemic: longitudinal investigation of patterns dependent on age, sex, and family history of mental illness
Depressive symptoms in youth before and during the COVID-19 pandemic: longitudinal investigation of patterns dependent on age, sex, and family history of mental illness Open
Background Cross-sectional studies report high levels of depressive symptoms during the COVID-19 pandemic, especially in youth and females. However, longitudinal research comparing depressive symptoms before and during the pandemic is lack…
View article: Familial traits of bipolar disorder: A systematic review and meta‐analysis
Familial traits of bipolar disorder: A systematic review and meta‐analysis Open
Background Genetic studies of bipolar disorder (BD) have shown varied results, which is in part because of the heterogeneity of the disorder. Identifying clinical phenotypes of BD could reduce variability and benefit research. Since BD has…
View article: Visual memory and psychotic symptoms in youth
Visual memory and psychotic symptoms in youth Open
Lower visual memory performance is associated with psychotic symptoms among youth, regardless of general cognitive ability. This finding may inform future targeted early interventions.
View article: Basic symptoms in offspring of parents with mood and psychotic disorders
Basic symptoms in offspring of parents with mood and psychotic disorders Open
Background Basic symptoms, defined as subjectively perceived disturbances in thought, perception and other essential mental processes, have been established as a predictor of psychotic disorders. However, the relationship between basic sym…
View article: Cognitive Performance in First-Degree Relatives of Individuals With vs Without Major Depressive Disorder
Cognitive Performance in First-Degree Relatives of Individuals With vs Without Major Depressive Disorder Open
A general impairment in cognition is a feature of familial disposition for MDD. Cognition may contribute to early identification of risk for depression and may be examined as potential target for early intervention.
View article: Attention-deficit hyperactivity disorder and anxiety disorders as precursors of bipolar disorder onset in adulthood
Attention-deficit hyperactivity disorder and anxiety disorders as precursors of bipolar disorder onset in adulthood Open
Background Attention-deficit hyperactivity disorder (ADHD) and anxiety disorders have been proposed as precursors of bipolar disorder, but their joint and relative roles in the development of bipolar disorder are unknown. Aims To test the …
View article: Hot and cold executive functions in youth with psychotic symptoms
Hot and cold executive functions in youth with psychotic symptoms Open
Background Psychotic symptoms are common in children and adolescents and may be early manifestations of liability to severe mental illness (SMI), including schizophrenia. SMI and psychotic symptoms are associated with impairment in executi…
View article: Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder
Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder Open
Background: The Canadian Network for Mood and Anxiety Treatments (CANMAT) has revised its 2009 guidelines for the management of major depressive disorder (MDD) in adults by updating the evidence and recommendations. The target audiences fo…
View article: Specific anxiety disorders and subsequent risk for bipolar disorder: a nationwide study
Specific anxiety disorders and subsequent risk for bipolar disorder: a nationwide study Open
Anxiety disorders are highly prevalent in people with bipolar disorder1 and substantially worsen the course of the illness as well as treatment response2-4. Anxiety disorders typically precede the onset of bipolar disorder2, 5, 6 and might…
View article: Long-term effects of depression treatment
Long-term effects of depression treatment Open
In most cases, depression is a recurrent or chronic condition that affects individuals over the course of their lifetime.1Judd LL Akiskal HS Maser JD et al.A prospective 12-year study of subsyndromal and syndromal depressive symptoms in un…