Explanipedia

A large long‐term database of Gaucher disease patients demonstrates increased risk of lymphoma and myeloma, but not of solid tumours Open

Majdolen Istaiti, Tama Dinur, Ora Paltiel, Barbara Silverman, Shoshana Revel‐Vilk , et al. · 2025

Background Gaucher disease (GD) has been variably associated with cancer risk, with conflicting reports in the literature. Understanding the true cancer burden is critical for patient care and genetic counselling. Aim To determine the over…

Development of uMUC-1 Targeted NEMO Particles with pH-Activatable MRI Signals for Enhanced Detection of Malignant Breast Cancer Cells Open

Dhruvi M. Panchal, Angela M. Gorman, Celia Martinez de la Torre, Barbara Silverman, Anthony J. Scalzo , et al. · 2025

Magnetic resonance imaging (MRI) detects more breast cancers than mammography due to its superior soft tissue contrast; however, it still misdiagnoses 40% of benign tumors as malignant due to clinically used nonspecific contrast agents (e.…

Modeling and the use of surrogate endpoints: Is this a valid approach? Open

Uri Ladabaum, Luuk A van Duuren, Elizabeth Half, Zohar Levi, Barbara Silverman , et al. · 2024

Development of novel colorectal cancer (CRC) screening tests is a dynamic field. Decision analytic modeling based on inputs derived from rigorous prospective studies informs CRC screening guidelines. Exploratory modeling may have a place i…

The Use of National Cancer Registry Data for Breast Cancer Family History Assessment in Premenopausal Women Open

Gabriel Chodick, Barbara Silverman, Lital Keinan-Boker · 2024

Background: Population-based cancer registries are the best source of information to measure cancer burden. However, little is done to use this information for individual cancer risk assessment. In this study, we aimed at identifying women…

Place of Death for Israeli Cancer Patients Over a 20-Year Period: Reducing Hospital Deaths, but Barriers Remain Open

Yuval Shalev Many, Pesach Shvartzman, Ido Wolf, Barbara Silverman · 2023

Background Cancer remains a leading cause of mortality worldwide. While the main focus of palliative care (PC) is quality of life, the elements that comprise the quality of death are often overlooked. Dying at home, with home-hospice-care …

Risk of Cancer in Pediatric-Onset Inflammatory Bowel Diseases: A Nation-Wide Study from the Epi-Iirn Open

Ohad Atia, Sasha Harel, Shira Greenfeld, Natan Ledderman, Revital Kariv , et al. · 2021

Secondary Cancer after Meningioma Diagnosis – an Israeli National Study Open

Maya Ben Lassan, Yael Laitman, Lital Keinan‐Boker, Barbara Silverman, Eitan Friedman · 2021

A COVID-19 call center for healthcare providers: dealing with rapidly evolving health policy guidelines Open

Aharona Glatman‐Freedman, Michal Bromberg, Amit Ram, Miri Lutski, Ravit Bassal , et al. · 2020

Uterine cancer in Jewish Israeli <i>BRCA1/2</i> mutation carriers Open

Yael Laitman, Rachel Michaelson‐Cohen, Einat Levi, Rakefet Chen‐Shtoyerman, Orit Reish , et al. · 2018

Background BRCA1/2 mutation carriers have an increased risk of developing ovarian cancer, leading to the recommendation of risk‐reducing salpingo‐oophorectomy (RRSO) at 35‐40 years of age. The role, if any, that BRCA mutations play in conf…

Deliveries following fertility preservation by ovarian tissue cryopreservation without autotransplantation—what should be expected? Open

Daniel Lantsberg, Adel Farhi, Inna Zaslavsky‐Paltiel, Barbara Silverman, Liat Lerner‐Geva , et al. · 2018

42P Is there a delay in diagnosis of lung cancer in women? Open

Yaakov Tolwin, Barbara Silverman, Nir Peled · 2018

Incidence patterns of colorectal cancers in four countries of the Middle East Cancer Consortium (Cyprus, Jordan, Israel, and İzmir, Turkey) compared with those in the United States Surveillance, Epidemiology, and End Results Program Open

Sultan Eser, Jenny C. Chang, Haris Charalambous, Barbara Silverman, Anna Demetriou , et al. · 2018

MECC countries comprise both high- and low-risk populations for CRCs. However, increasing trends in low-risk populations have been alarming. Thus, the need for implementing tailored primary and secondary prevention programs in the region i…

Time Trends in the Incidence and Mortality of Ovarian Cancer in Ireland, Northern Ireland, and Israel, 1994–2013 Open

Lital Keinan‐Boker, Barbara Silverman, Paul M. Walsh, Anna Gavin, Catherine Hayes · 2017

Time trends in ovarian cancer incidence (decreasing) and mortality (decreasing) were similar in Ireland, NI, and Israeli Jews, following global trends, with a more prominent incidence decline in Israeli Jews. Decreasing mortality trends ar…

Primary Peritoneal Serous Carcinoma in Men: A Rare and Non-BRCA-associated Entity Open

Susan L. Neuhausen, Hagit Shani, Lital Keinan‐Boker, Linda Steele, Barbara Silverman , et al. · 2017

PPSC is a rare neoplasm, seemingly not associated with BRCA mutations in men, and fallopian tube epithelial cell implants may contribute to its development.

0623 INCREASED RISK FOR CANCER IN YOUNG PATIENTS WITH SEVERE OBSTRUCTIVE SLEEP APNEA Open

Ronen Brenner, Shaye Kivity, Marina Peker, Daniel Reinhorn, Lital Keinan‐Boker , et al. · 2017

An increase in cancer aggressiveness was reported in obstructive sleep apnea (OSA) animal models, and in sleep deprivation or insomnia. however, there is a need for clinical evidence supporting a direct correlation between OSA and cancer i…

Disease management in the treatment of patients with chronic heart failure who have universal access to health care: a randomized controlled trial Open

Ofra Kalter‐Leibovici, Dov Freimark, Laurence S. Freedman, Galit Kaufman, Arnona Ziv , et al. · 2017

Survey of Breast Cancer Incidence in the Middle East and the United States Open

Barbara Silverman · 2017

Breast cancer is the most frequent cancer and the leading cause of cancer deaths in women worldwide. Regional comparisons of breast cancer incidence can shed light on population and health care factors that contribute to differences betwee…

ecancermedicalscience Open

Nava Siegelmann‐Danieli, Barbara Silverman, Aviad Zick, Anat Beit-Or, Itzhak Katzir , et al. · 2016

The Oncotype DX Recurrence Score is a validated prognosticator in oestrogen receptor positive (ER+) breast cancer. Our retrospective analysis of a prospectively defined cohort summarises the clinical implications associated with Oncotype D…

Cancer burden in four countries of the Middle East Cancer Consortium (Cyprus; Jordan; Israel; Izmir (Turkey)) with comparison to the United States surveillance; epidemiology and end results program Open

Hoda Anton‐Culver, Jenny Chang, Freddie Bray, Ariana Znaor, Lisa Stevens , et al. · 2016

It is important that population-based cancer registries provide accurate and reliable data for public health purposes. These data are essential data for planning of cancer control and prevention. In this study, we examined cancer incidence…

Second Primary Cancers After Primary Breast Cancer Diagnosis in Israeli Women, 1992 to 2006 Open

Barbara Silverman, Irena Lipshitz, Lital Keinan‐Boker · 2016

Purpose Improvements in early detection and treatment have resulted in improved long-term survival from breast cancer, which increases the likelihood of the occurrence of second primary cancers. We calculated the risk of second primary can…

Diabetes, prostate cancer screening and risk of low- and high-grade prostate cancer: an 11 year historical population follow-up study of more than 1 million men Open

Rachel Dankner, Paolo Boffetta, Lital Keinan‐Boker, Ran D. Balicer, A. Berlin , et al. · 2016

ClinicalTrials.gov NCT02072902.

Trends of Thyroid Cancer in Israel: 1980–2012 Open

Lital Keinan‐Boker, Barbara Silverman · 2016

The Israeli secular trends of thyroid cancer incidence (increasing), mortality (mostly stable), and survival (modestly increasing) closely follow reported global trends.

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