Barbara Y. Braz
YOU?
Author Swipe
View article: Structural interhemispheric connectivity defects in mouse models of BBSOAS: Insights from high spatial resolution 3D white matter tractography
Structural interhemispheric connectivity defects in mouse models of BBSOAS: Insights from high spatial resolution 3D white matter tractography Open
White matter (WM) tract formation and axonal pathfinding are major processes in brain development allowing to establish precise connections between targeted structures. Disruptions in axon pathfinding and connectivity impairments will lead…
View article: Traiter des défauts transitoires précoces des neurones dans un modèle murin de la maladie de Huntington empêche l’apparition de symptômes à l’âge adulte
Traiter des défauts transitoires précoces des neurones dans un modèle murin de la maladie de Huntington empêche l’apparition de symptômes à l’âge adulte Open
International audience
View article: Preserved Motility after Neonatal Dopaminergic Lesion Relates to Hyperexcitability of Direct Pathway Medium Spiny Neurons
Preserved Motility after Neonatal Dopaminergic Lesion Relates to Hyperexcitability of Direct Pathway Medium Spiny Neurons Open
In Parkinson's disease patients and rodent models, dopaminergic neuron loss (DAN) results in severe motor disabilities. In contrast, general motility is preserved after early postnatal DAN loss in rodents. Here we used mice of both sexes t…
View article: Huntingtin coordinates dendritic spine morphology and function through cofilin-mediated control of the actin cytoskeleton
Huntingtin coordinates dendritic spine morphology and function through cofilin-mediated control of the actin cytoskeleton Open
Compelling evidence indicates that in Huntington's disease (HD), mutation of huntingtin (HTT) alters several aspects of early brain development such as synaptogenesis. It is not clear to what extent the partial loss of wild-type HTT functi…
View article: Huntington’s disease alters human neurodevelopment
Huntington’s disease alters human neurodevelopment Open
Neural progenitors disrupted Symptoms of Huntington's disease (HD) manifest in adulthood despite the aberrant protein being present much earlier in persons carrying the disease-causing mutation. Barnat et al. studied the cellular effects o…
View article: Chronic Corticosterone Elevation Suppresses Adult Hippocampal Neurogenesis by Hyperphosphorylating Huntingtin
Chronic Corticosterone Elevation Suppresses Adult Hippocampal Neurogenesis by Hyperphosphorylating Huntingtin Open
Chronic exposure to stress is a major risk factor for neuropsychiatric disease, and elevated plasma corticosterone (CORT) correlates with reduced levels of both brain-derived neurotrophic factor (BDNF) and hippocampal neurogenesis. Precise…
View article: Properties of the corticostriatal long term depression induced by medial prefrontal cortex high frequency stimulation in vivo
Properties of the corticostriatal long term depression induced by medial prefrontal cortex high frequency stimulation in vivo Open
View article: Compulsive Social Behavior Emerges after Selective Ablation of Striatal Cholinergic Interneurons
Compulsive Social Behavior Emerges after Selective Ablation of Striatal Cholinergic Interneurons Open
The mechanisms underlying social dysfunction in neuropsychiatric conditions such as obsessive-compulsive disorder and Tourette syndrome remain uncertain. However, it is known that dysfunctions in basal ganglia, including a reduced number o…
View article: Rol de la dopamina en la maduración postnatal del sistema córticoestriatal y conductas dependientes del mismo
Rol de la dopamina en la maduración postnatal del sistema córticoestriatal y conductas dependientes del mismo Open
Los ganglios de la base (BG) son núcleos subcorticales interconectados con la corteza cerebral que estáninvolucrados en el control motor voluntario y distintos aspectos de la conducta y el aprendizaje. Ladopamina es un regulador clave del …
View article: Altered Corticostriatal Connectivity and Exploration/Exploitation Imbalance Emerge as Intermediate Phenotypes for a Neonatal Dopamine Dysfunction
Altered Corticostriatal Connectivity and Exploration/Exploitation Imbalance Emerge as Intermediate Phenotypes for a Neonatal Dopamine Dysfunction Open