Barbora Beňová
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View article: The epileptogenic zone in children with tuberous sclerosis complex is characterized by prominent features of focal cortical dysplasia
The epileptogenic zone in children with tuberous sclerosis complex is characterized by prominent features of focal cortical dysplasia Open
Objective Patients with tuberous sclerosis complex (TSC) present with drug‐resistant epilepsy in about 60% of cases, and evaluation for epilepsy surgery may be warranted. Correct delineation of the epileptogenic zone (EZ) among multiple dy…
View article: Fetal Brain Magnetic Resonance Imaging Findings Predict Neurodevelopment in Children with Tuberous Sclerosis Complex
Fetal Brain Magnetic Resonance Imaging Findings Predict Neurodevelopment in Children with Tuberous Sclerosis Complex Open
Fetal cerebral lesion scores correlate with neurodevelopment and ASD at 2 years in children with TSC.
View article: Prevention of Epilepsy in Infants with Tuberous Sclerosis Complex in the <scp>EPISTOP</scp> Trial
Prevention of Epilepsy in Infants with Tuberous Sclerosis Complex in the <span>EPISTOP</span> Trial Open
Objective Epilepsy develops in 70 to 90% of children with tuberous sclerosis complex (TSC) and is often resistant to medication. Recently, the concept of preventive antiepileptic treatment to modify the natural history of epilepsy has been…
View article: Prediction of Neurodevelopment in Infants With Tuberous Sclerosis Complex Using Early EEG Characteristics
Prediction of Neurodevelopment in Infants With Tuberous Sclerosis Complex Using Early EEG Characteristics Open
Tuberous Sclerosis Complex (TSC) is a multisystem genetic disorder with a high risk of early-onset epilepsy and a high prevalence of neurodevelopmental comorbidities, including intellectual disability and autism spectrum disorder (ASD). Th…
View article: A novel effective paradigm of intraoperative electrical stimulation mapping in children
A novel effective paradigm of intraoperative electrical stimulation mapping in children Open
OBJECTIVE Resective epilepsy surgery is an established treatment method for children with focal intractable epilepsy, but the use of this method introduces the risk of postsurgical motor deficits. Electrical stimulation mapping (ESM), used…
View article: Peer Review #2 of "Cognitive performance in distinct groups of children undergoing epilepsy surgery—a single-centre experience (v0.1)"
Peer Review #2 of "Cognitive performance in distinct groups of children undergoing epilepsy surgery—a single-centre experience (v0.1)" Open
Background.We aimed first to describe trends in cognitive performance over time in a large patient cohort (n= 203) from a single tertiary centre for paediatric epilepsy surgery over the period of 16 years divided in two (developing -pre-20…
View article: Cognitive performance in distinct groups of children undergoing epilepsy surgery—a single-centre experience
Cognitive performance in distinct groups of children undergoing epilepsy surgery—a single-centre experience Open
Background We aimed first to describe trends in cognitive performance over time in a large patient cohort ( n = 203) from a single tertiary centre for paediatric epilepsy surgery over the period of 16 years divided in two (developing—pre-2…
View article: Early Clinical Predictors of Autism Spectrum Disorder in Infants with Tuberous Sclerosis Complex: Results from the EPISTOP Study
Early Clinical Predictors of Autism Spectrum Disorder in Infants with Tuberous Sclerosis Complex: Results from the EPISTOP Study Open
Autism spectrum disorder (ASD) is highly prevalent in subjects with Tuberous Sclerosis Complex (TSC), but we are not still able to reliably predict which infants will develop ASD. This study aimed to identify the early clinical markers of …
View article: Genotype‐phenotype correlations in focal malformations of cortical development: a pathway to integrated pathological diagnosis in epilepsy surgery
Genotype‐phenotype correlations in focal malformations of cortical development: a pathway to integrated pathological diagnosis in epilepsy surgery Open
Malformations of cortical development ( MCD ) comprise a broad spectrum of developmental brain abnormalities. Patients presenting with MCD s often suffer from drug‐resistant focal epilepsy, and some become candidates for epilepsy surgery. …
View article: Psychometric properties of the Czech version of the Stigma Scale of Epilepsy
Psychometric properties of the Czech version of the Stigma Scale of Epilepsy Open
Although significant attention has been devoted to analyzing stigma associated with epilepsy, there is still a significant lack of valid and reliable instruments. We aimed to validate the 23-item Czech version of the Stigma Scale of Epilep…
View article: Towards in vivo focal cortical dysplasia phenotyping using quantitative MRI
Towards in vivo focal cortical dysplasia phenotyping using quantitative MRI Open
Focal cortical dysplasias (FCDs) are a range of malformations of cortical development each with specific histopathological features. Conventional radiological assessment of standard structural MRI is useful for the localization of lesions …
View article: Novel Histopathological Patterns in Cortical Tubers of Epilepsy Surgery Patients with Tuberous Sclerosis Complex
Novel Histopathological Patterns in Cortical Tubers of Epilepsy Surgery Patients with Tuberous Sclerosis Complex Open
textabstractTuberous Sclerosis Complex (TSC) is a genetic hamartoma syndrome frequently associated with severe intractable epilepsy. In some TSC patients epilepsy surgery is a promising treatment option provided that the epileptogenic zone…