Bart J. Emmer
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View article: White matter lesion effect modification of aspirin and unfractionated heparin during endovascular stroke treatment
White matter lesion effect modification of aspirin and unfractionated heparin during endovascular stroke treatment Open
Objectives Periprocedural aspirin or unfractionated heparin during endovascular treatment in acute ischemic stroke increases symptomatic intracranial hemorrhage (sICH) risk without improving functional outcome. White matter lesions (WMLs) …
View article: Direct Endovascular Versus Bridging Therapy in M2 Segment Occlusion of Middle Cerebral Artery: A MR CLEAN Registry Study
Direct Endovascular Versus Bridging Therapy in M2 Segment Occlusion of Middle Cerebral Artery: A MR CLEAN Registry Study Open
BACKGROUND: The optimal strategy for managing M2 segment occlusions of the middle cerebral artery, whether with direct endovascular treatment (EVT) or bridging therapy with intravenous thrombolysis (IVT) before EVT, remains unclear. This s…
View article: Associations between clinicoradiological variables and onset-to-imaging time in acute ischemic stroke: A retrospective study
Associations between clinicoradiological variables and onset-to-imaging time in acute ischemic stroke: A retrospective study Open
Among AIS patients included in the MR CLEAN registry, lower ASPECTS, presence of leukoaraiosis and a higher collateral score are associated with a late onset-to-imaging time (>4.5 h; >6 h after stroke onset). The accuracy of the associatio…
View article: Cost-effectiveness of intra-arterial thrombolysis after successful thrombectomy
Cost-effectiveness of intra-arterial thrombolysis after successful thrombectomy Open
Objectives To study the cost-effectiveness of additional intra-arterial thrombolysis (IA lysis) after successful recanalization with endovascular thrombectomy (EVT). Design A cost-effectiveness model was used to estimate both direct medica…
View article: Association of CRP levels and clinical and radiological outcomes in patients with large-vessel occlusion stroke: A MR CLEAN Registry study
Association of CRP levels and clinical and radiological outcomes in patients with large-vessel occlusion stroke: A MR CLEAN Registry study Open
Introduction: Inflammation is important in the pathogenesis of acute ischemic stroke (AIS). The association between CRP and outcomes in patients with large vessel occlusion (LVO) stroke receiving endovascular therapy (EVT) has not been ful…
View article: Outcomes After Thrombectomy for Acute Ischemic Stroke Related to Type of Stent Retriever; a MR CLEAN Registry Study
Outcomes After Thrombectomy for Acute Ischemic Stroke Related to Type of Stent Retriever; a MR CLEAN Registry Study Open
Purpose Endovascular treatment (EVT) with a stent retriever is known to be effective and safe in patients with acute ischemic stroke due to large vessel occlusion. We aimed to compare the most used stent retrievers in a nationwide registry…
View article: National trends in patient characteristics, interventional techniques and outcomes of endovascular treatment for acute ischaemic stroke: Final results of the MR CLEAN Registry (2014–2018)
National trends in patient characteristics, interventional techniques and outcomes of endovascular treatment for acute ischaemic stroke: Final results of the MR CLEAN Registry (2014–2018) Open
Introduction: Endovascular thrombectomy (EVT) procedures and workflow have evolved over the years. We examined trends in patient characteristics, EVT techniques and outcomes over 5 years in the Netherlands. Patients and methods: Data from …
View article: Optimised medical therapy alone versus optimised medical therapy plus revascularisation for asymptomatic or low-to-intermediate risk symptomatic carotid stenosis (ECST-2): 2-year interim results of a multicentre randomised trial
Optimised medical therapy alone versus optimised medical therapy plus revascularisation for asymptomatic or low-to-intermediate risk symptomatic carotid stenosis (ECST-2): 2-year interim results of a multicentre randomised trial Open
View article: Automated collateral assessment restricted to the hypoperfused area for distal vessel occlusions in ischemic stroke
Automated collateral assessment restricted to the hypoperfused area for distal vessel occlusions in ischemic stroke Open
View article: Deep generative models for vessel segmentation in CT angiography of the brain
Deep generative models for vessel segmentation in CT angiography of the brain Open
Automated vessel segmentation in brain CT angiography (CTA) remains challenging despite the potential benefit of applications. Expert acquisition of reference vessel segmentations is a laborious task. We propose an unsupervised generative …
View article: Changes in hemorrhage pattern on consecutive non-contrast CT scans in non-aneurysmal subarachnoid hemorrhage patients
Changes in hemorrhage pattern on consecutive non-contrast CT scans in non-aneurysmal subarachnoid hemorrhage patients Open
View article: Non-Optic Glioma-like Lesions in Adult Neurofibromatosis Type 1 Patients
Non-Optic Glioma-like Lesions in Adult Neurofibromatosis Type 1 Patients Open
Background/Objectives: Physicians face clinical dilemmas in the diagnosis of non-optic intraparenchymal lesions on MRI brain scans of patients with neurofibromatosis type 1. As the incidence and evolution of these lesions into adulthood re…
View article: Quality Improvement Intervention for Reducing Acute Treatment Times in Ischemic Stroke
Quality Improvement Intervention for Reducing Acute Treatment Times in Ischemic Stroke Open
Importance Efficient care processes are crucial to minimize treatment delays and improve outcome after endovascular thrombectomy (EVT) in patients with ischemic stroke. A potential means to improve care processes is performance feedback. O…
View article: Association between coagulation activity and clinical and imaging outcomes in acute ischemic stroke patients - A sub-study of the MR CLEAN NO-IV trial
Association between coagulation activity and clinical and imaging outcomes in acute ischemic stroke patients - A sub-study of the MR CLEAN NO-IV trial Open
Despite temporary significant increases in enzyme:inhibitor complexes in the IVT+EVT group, but not in the EVT alone group, there were no significant associations with final infarct volume and clinical outcomes.
View article: Deep learning for efficient reconstruction of highly accelerated 3D FLAIR MRI in neurological deficits
Deep learning for efficient reconstruction of highly accelerated 3D FLAIR MRI in neurological deficits Open
Objective To compare compressed sensing (CS) and the Cascades of Independently Recurrent Inference Machines (CIRIM) with respect to image quality and reconstruction times when 12-fold accelerated scans of patients with neurological deficit…
View article: Association of first-line thrombectomy technique and outcome in late-window large vessel occlusion strokes: A post hoc analysis of the MR CLEAN-LATE trial
Association of first-line thrombectomy technique and outcome in late-window large vessel occlusion strokes: A post hoc analysis of the MR CLEAN-LATE trial Open
Background: This study aimed to compare direct aspiration, stent retriever, and the combined thrombectomy technique on clinical, safety, and technical outcomes in late-window stroke patients included in the MR CLEAN-LATE trial. Methods: Th…
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We have read with interest the comment by Su et al and their own recent publication on this subject.[1][1] Their results show that embolization with Onyx (Medtronic) is a feasible and safe method for embolization of anterior cranial fossa …
View article: Thrombus Imaging Characteristics to Predict Early Recanalization in Anterior Circulation Large Vessel Occlusion Stroke
Thrombus Imaging Characteristics to Predict Early Recanalization in Anterior Circulation Large Vessel Occlusion Stroke Open
The early management of transferred patients with a large vessel occlusion (LVO) stroke could be improved by identifying patients who are likely to recanalize early. We aim to predict early recanalization based on patient clinical and thro…
View article: Impact of Intracranial Volume and Brain Volume on the Prognostic Value of Computed Tomography Perfusion Core Volume in Acute Ischemic Stroke
Impact of Intracranial Volume and Brain Volume on the Prognostic Value of Computed Tomography Perfusion Core Volume in Acute Ischemic Stroke Open
Background: Computed tomography perfusion (CTP)-estimated core volume is associated with functional outcomes in acute ischemic stroke. This relationship might differ among patients, depending on brain volume. Materials and Methods: We retr…
View article: Value of Automatically Derived Full Thrombus Characteristics: An Explorative Study of Their Associations with Outcomes in Ischemic Stroke Patients
Value of Automatically Derived Full Thrombus Characteristics: An Explorative Study of Their Associations with Outcomes in Ischemic Stroke Patients Open
(1) Background: For acute ischemic strokes caused by large vessel occlusion, manually assessed thrombus volume and perviousness have been associated with treatment outcomes. However, the manual assessment of these characteristics is time-c…
View article: Time to Treatment With Intravenous Thrombolysis Before Thrombectomy and Functional Outcomes in Acute Ischemic Stroke
Time to Treatment With Intravenous Thrombolysis Before Thrombectomy and Functional Outcomes in Acute Ischemic Stroke Open
Importance The benefit of intravenous thrombolysis (IVT) for acute ischemic stroke declines with longer time from symptom onset, but it is not known whether a similar time dependency exists for IVT followed by thrombectomy. Objective To de…
View article: Deep learning-based white matter lesion volume on CT is associated with outcome after acute ischemic stroke
Deep learning-based white matter lesion volume on CT is associated with outcome after acute ischemic stroke Open
View article: Intravenous Thrombolysis Before Endovascular Treatment in Posterior Circulation Occlusions: A MR CLEAN Registry Study
Intravenous Thrombolysis Before Endovascular Treatment in Posterior Circulation Occlusions: A MR CLEAN Registry Study Open
BACKGROUND: The effectiveness of intravenous thrombolysis (IVT) before endovascular treatment (EVT) has been investigated in randomized trials and meta-analyses. These studies mainly concerned anterior circulation occlusions. We aimed to i…
View article: Transarterial Embolization of Anterior Cranial Fossa Dural AVFs as a First-Line Approach: A Single-Center Study
Transarterial Embolization of Anterior Cranial Fossa Dural AVFs as a First-Line Approach: A Single-Center Study Open
Treatment of anterior cranial fossa dural AVFs using transarterial embolization with n-BCA as a first-line approach is a safe and feasible first-line treatment strategy. No visual complications due to embolization through the ophtha…
View article: Costs and health effects of CT perfusion-based selection for endovascular thrombectomy within 6 hours of stroke onset: a model-based health economic evaluation
Costs and health effects of CT perfusion-based selection for endovascular thrombectomy within 6 hours of stroke onset: a model-based health economic evaluation Open
Background Although CT perfusion (CTP) is often incorporated in acute stroke workflows, it remains largely unclear what the associated costs and health implications are in the long run of CTP-based patient selection for endovascular treatm…
View article: Outcome of patients with multivessel occlusion stroke after endovascular treatment
Outcome of patients with multivessel occlusion stroke after endovascular treatment Open
Introduction: Little is known about the implications of multivessel occlusions (MVO) in large vessel occlusion stroke patients who undergo endovascular treatment (EVT). Patients and methods: We report data from the MR CLEAN Registry: a pro…
View article: Development and Validation of a Prediction Model for Failure of the Transfemoral Approach of Endovascular Treatment for Large Vessel Occlusion Acute Ischemic Stroke
Development and Validation of a Prediction Model for Failure of the Transfemoral Approach of Endovascular Treatment for Large Vessel Occlusion Acute Ischemic Stroke Open
Introduction: Extracranial vascular characteristics determine the accessibility of the large vessel intracranial occlusion for endovascular treatment (EVT) in acute ischemic stroke. We developed and validated a prediction model for failure…
View article: Clinical consequence of vessel perforations during endovascular treatment of acute ischemic stroke
Clinical consequence of vessel perforations during endovascular treatment of acute ischemic stroke Open
View article: Endovascular treatment of patients with stroke caused by anterior cerebral artery occlusions
Endovascular treatment of patients with stroke caused by anterior cerebral artery occlusions Open
View article: Early Intubation in Endovascular Therapy for Basilar Artery Occlusion: A Post Hoc Analysis of the BASICS Trial
Early Intubation in Endovascular Therapy for Basilar Artery Occlusion: A Post Hoc Analysis of the BASICS Trial Open
BACKGROUND: The optimal anesthetic management for endovascular therapy (EVT) in patients with posterior circulation stroke remains unclear. Our objective was to investigate the impact of early intubation in patients enrolled in the BASICS …