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View article: P-400 Efficiency of Thawed Oocytes after Elective Oocyte Cryopreservation in Women with Diminished Ovarian Reserve and/or Advanced Age: A Ten-Year Follow-Up Study
P-400 Efficiency of Thawed Oocytes after Elective Oocyte Cryopreservation in Women with Diminished Ovarian Reserve and/or Advanced Age: A Ten-Year Follow-Up Study Open
Study question What is the efficiency of thawed oocytes in women with diminished ovarian reserve (DOR) and/or advanced age who underwent elective oocyte cryopreservation (EOC)? Summary answer Among women with DOR and/or advanced age who ut…
View article: O-107 A revised ESHRE/ALPHA consensus on oocyte and embryo assessment: 5 essential takeaways
O-107 A revised ESHRE/ALPHA consensus on oocyte and embryo assessment: 5 essential takeaways Open
Study question What are the current recommended criteria for morphological assessment of oocytes, zygotes and embryos? Summary answer The present ESHRE/Alpha Scientists in Reproductive Medicine consensus document provides several novel rec…
View article: The Istanbul consensus update: a revised ESHRE/ALPHA consensus on oocyte and embryo static and dynamic morphological assessment,
The Istanbul consensus update: a revised ESHRE/ALPHA consensus on oocyte and embryo static and dynamic morphological assessment, Open
STUDY QUESTION What are the current recommended criteria for morphological assessment of oocytes, zygotes, and embryos? SUMMARY ANSWER The present ESHRE/Alpha Scientists in Reproductive Medicine consensus document provides several novel re…
View article: O-089 Association of pituitary suppression method with euploid blastocyst yield in preimplantation genetic testing for aneuploidy (PGT-A) cycles
O-089 Association of pituitary suppression method with euploid blastocyst yield in preimplantation genetic testing for aneuploidy (PGT-A) cycles Open
Study question Do progestin primed ovarian stimulation (PPOS) cycles have lower euploidy yield compared to pituitary suppression with gonadotropin releasing hormone (GnRH) antagonists? Summary answer The choice of pituitary suppression met…
View article: O-240 Embryo assessment: the Istanbul consensus revised
O-240 Embryo assessment: the Istanbul consensus revised Open
Study question What are the current recommended criteria for morphological assessment of oocytes, zygotes and embryos? Summary answer The present ESHRE/Alpha Scientists in Reproductive Medicine consensus document provides several novel rec…
View article: ART in Europe, 2019: results generated from European registries by ESHRE
ART in Europe, 2019: results generated from European registries by ESHRE Open
STUDY QUESTION What are the data and trends on ART and IUI cycle numbers and their outcomes, and on fertility preservation (FP) interventions, reported in 2019 as compared to previous years? SUMMARY ANSWER The 23rd ESHRE report highlights …
View article: Comparing performance between clinics of an embryo evaluation algorithm based on time-lapse images and machine learning
Comparing performance between clinics of an embryo evaluation algorithm based on time-lapse images and machine learning Open
Purpose This article aims to assess how differences in maternal age distributions between IVF clinics affect the performance of an artificial intelligence model for embryo viability prediction and proposes a method to account for such diff…
View article: An annotated human blastocyst dataset to benchmark deep learning architectures for in vitro fertilization
An annotated human blastocyst dataset to benchmark deep learning architectures for in vitro fertilization Open
Medical Assisted Reproduction proved its efficacy to treat the vast majority forms of infertility. One of the key procedures in this treatment is the selection and transfer of the embryo with the highest developmental potential. To assess …
View article: Is double frozen blastocyst transfer better than sequential single frozen blastocyst transfers in womenover >35 years of age?
Is double frozen blastocyst transfer better than sequential single frozen blastocyst transfers in womenover >35 years of age? Open
Freeze-all blastocyst transfer cycles women aged >35 Is double frozen blastocyst transfer better than sequential single frozen blastocyst transfers in womenover >35 years of age?
View article: O-285 Artificial intelligence algorithms reach expert-level accuracy in automated grading of blastocyst morphology assessment based on static embryo images and Gardner criteria
O-285 Artificial intelligence algorithms reach expert-level accuracy in automated grading of blastocyst morphology assessment based on static embryo images and Gardner criteria Open
Study question Can artificial intelligence (AI) algorithms reach expert-level accuracy in blastocyst morphology assessment according to Gardner criteria? Summary answer The prediction accuracy of the best performing AI algorithm (Deit), ou…
View article: ART in Europe, 2018: results generated from European registries by ESHRE
ART in Europe, 2018: results generated from European registries by ESHRE Open
STUDY QUESTION What are the data and trends on ART and IUI cycle numbers and their outcomes, and on fertility preservation (FP) interventions, reported in 2018 as compared to previous years? SUMMARY ANSWER The 22nd ESHRE report shows a con…
View article: What is the optimum number of follicular flushing in mono-follicular IVF cycles in poor responder women population?
What is the optimum number of follicular flushing in mono-follicular IVF cycles in poor responder women population? Open
Flushing confers a benefit for oocyte recover rates in mono-follicular IVF cycles in poor responder women. However, more than three attempts at flushing were not associated with good outcome.
View article: ART in Europe, 2017: results generated from European registries by ESHRE
ART in Europe, 2017: results generated from European registries by ESHRE Open
STUDY QUESTION What are the data on ART and IUI cycles, and fertility preservation (FP) interventions reported in 2017 as compared to previous years, as well as the main trends over the years? SUMMARY ANSWER The 21st ESHRE report on ART an…
View article: Spontaneous and in vitro fertilization pregnancies have comparable first trimester screening profiles for Down syndrome
Spontaneous and in vitro fertilization pregnancies have comparable first trimester screening profiles for Down syndrome Open
These results support the notion that uncomplicated singleton IVF pregnancies have similar first trimester screening profiles to spontaneous conceptions.
View article: Multi-center evaluation of oxidation-reduction potential by the MiOXSYS in males with abnormal semen
Multi-center evaluation of oxidation-reduction potential by the MiOXSYS in males with abnormal semen Open
According to the World Health Organization (WHO), oxidative stress (OS) is a significant contributor to male infertility. Seminal OS can be measured by a number of assays, all of which are either costly or time sensitive and/or require lar…
View article: Luteal granulosa cells from natural cycles are more capable of maintaining their viability, steroidogenic activity and LH receptor expression than those of stimulated IVF cycles
Luteal granulosa cells from natural cycles are more capable of maintaining their viability, steroidogenic activity and LH receptor expression than those of stimulated IVF cycles Open
This study was funded by the School of Medicine, the Graduate School of Health Sciences of Koc University and Koç University Research Center for Translational Medicine (KUTTAM), equally funded by the Republic of Turkey Ministry of Developm…
View article: Spontaneous and IVF pregnancies have comparable first trimester screening profiles for Down syndrome
Spontaneous and IVF pregnancies have comparable first trimester screening profiles for Down syndrome Open
Objective:We aimed to compare the first trimester screening profiles of spontaneous (n=972) and IVF pregnancies (n=339) in a population of patients who had uncomplicated singleton pregnancies comparable for maternal age, gestation, BMI, an…
View article: FSH Stimulation promotes progesterone synthesis and output from human granulosa cells without luteinization
FSH Stimulation promotes progesterone synthesis and output from human granulosa cells without luteinization Open
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View article: Assessment of human embryo development using morphological criteria in an era of time-lapse, algorithms and ‘OMICS’: is looking good still important?
Assessment of human embryo development using morphological criteria in an era of time-lapse, algorithms and ‘OMICS’: is looking good still important? Open
With the worldwide move towards single embryo transfer there has been a renewed focus on the requirement for reliable means of assessing embryo viability. In an era of 'OMICS' technologies, and algorithms created through the use of time-la…
View article: The magnitude of gonadotoxicity of chemotherapy drugs on ovarian follicles and granulosa cells varies depending upon the category of the drugs and the type of granulosa cells
The magnitude of gonadotoxicity of chemotherapy drugs on ovarian follicles and granulosa cells varies depending upon the category of the drugs and the type of granulosa cells Open
These findings indicate that in vivo and in vitro cytotoxic actions of chemotherapy drugs on the ovarian follicles and granulosa cells vary depending upon the their mechanism of action and the nature of the granulosa cells.
View article: GnRH agonist leuprolide acetate does not confer any protection against ovarian damage induced by chemotherapy and radiation<i>in vitro</i>
GnRH agonist leuprolide acetate does not confer any protection against ovarian damage induced by chemotherapy and radiation<i>in vitro</i> Open
GnRH agonist treatment with chemotherapy does not prevent or ameliorate ovarian damage and follicle loss in vitro. These data can be useful when consulting a young patient who may wish to receive GnRH treatment with chemotherapy to protect…