Bashar Hamza
YOU?
Author Swipe
View article: 1001 CAT-248 (engineered NK cells expressing CD70 CAR, IL15, and TGFβ DNR) demonstrates in vivo expansion, tumor infiltration, and durable regression of multiple CD70-expressing xenograft tumors
1001 CAT-248 (engineered NK cells expressing CD70 CAR, IL15, and TGFβ DNR) demonstrates in vivo expansion, tumor infiltration, and durable regression of multiple CD70-expressing xenograft tumors Open
Background Durable and effective therapies are needed for solid tumors despite recent advances with targeted therapies and immunotherapies as many patients relapse or are refractory to these agents. Engineered immune cell therapies can be …
View article: Supplemental Movie 6 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Supplemental Movie 6 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Movie of A375 control cells in the tail over the course of 12 hours following injection.
View article: Figure S4 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Figure S4 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
YAP-AA does not enhance arrest, extravasation, or survival in circulation.
View article: Figure S4 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Figure S4 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
YAP-AA does not enhance arrest, extravasation, or survival in circulation.
View article: Supplemental Movie 6 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Supplemental Movie 6 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Movie of A375 control cells in the tail over the course of 12 hours following injection.
View article: Supplemental Movie 8 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Supplemental Movie 8 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Movie of A375 EV control cells in the inter-segmental vessels (ISVs) over the course of ~3 hours.
View article: Supplemental Movie 5 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Supplemental Movie 5 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Movie over 12 hours of a whole zebrafish embryo injected with YAP-AA over-expressing A375 cells
View article: Supplemental Movie 2 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Supplemental Movie 2 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Movie over 12 hours of the head of a zebrafish embryo injected with EV control A375 cells.
View article: Figure S3. from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Figure S3. from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
YAP-AA does not enhance entry into circulation from the injection site by 10HPI.
View article: Data from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Data from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
The oncogene YAP has been shown previously to promote tumor growth and metastasis. However, how YAP influences the behavior of tumor cells traveling within the circulatory system has not been as well explored. Given that rate-limiting step…
View article: Supplemental Movie 7 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Supplemental Movie 7 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Movie of A375 cells over-expressing YAP-AA in the tail over the course of 12 hours following injection.
View article: Supplemental Movie 4 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Supplemental Movie 4 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Movie over 12 hours of a whole zebrafish embryo injected with EV control A375 cells
View article: Supplemental Figure Legends from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Supplemental Figure Legends from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Legends for the supplemental figures and videos.
View article: Supplemental Movie 5 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Supplemental Movie 5 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Movie over 12 hours of a whole zebrafish embryo injected with YAP-AA over-expressing A375 cells
View article: Supplemental Figure Legends from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Supplemental Figure Legends from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Legends for the supplemental figures and videos.
View article: Supplemental Movie 9 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Supplemental Movie 9 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Movie of A375 cells over-expressing YAP-AA in the inter-segmental vessels (ISVs) over the course of ~3 hours.
View article: Data from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Data from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
The oncogene YAP has been shown previously to promote tumor growth and metastasis. However, how YAP influences the behavior of tumor cells traveling within the circulatory system has not been as well explored. Given that rate-limiting step…
View article: Figure S3. from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Figure S3. from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
YAP-AA does not enhance entry into circulation from the injection site by 10HPI.
View article: Figure S5. from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Figure S5. from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Tumor cell transit times do not vary between EV and YAP-AA cells
View article: Figure S5. from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Figure S5. from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Tumor cell transit times do not vary between EV and YAP-AA cells
View article: Supplemental Movie 3 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Supplemental Movie 3 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Movie over 12 hours of the head of a zebrafish embryo injected with YAP-AA-over-expressing A375 cells.
View article: Figure S6. from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Figure S6. from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Expression of YAP mutants.
View article: Supplemental Movie 7 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Supplemental Movie 7 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Movie of A375 cells over-expressing YAP-AA in the tail over the course of 12 hours following injection.
View article: Supplemental Movie 3 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Supplemental Movie 3 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Movie over 12 hours of the head of a zebrafish embryo injected with YAP-AA-over-expressing A375 cells.
View article: Supplemental Movie 1 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Supplemental Movie 1 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Movie showing blood flow through the Duct of Cuvier of a 2-day-old zebrafish embryo.
View article: Supplemental Movie 4 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Supplemental Movie 4 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Movie over 12 hours of a whole zebrafish embryo injected with EV control A375 cells
View article: Supplemental Movie 1 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Supplemental Movie 1 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Movie showing blood flow through the Duct of Cuvier of a 2-day-old zebrafish embryo.
View article: Figure S1 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Figure S1 from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
YAP-AA enhances metastasis using multiple quantification methods.
View article: Figure S2. from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
Figure S2. from YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation Open
Wild-type YAP does not enhance metastasis in zebrafish embryos.