Basil Kaufmann
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View article: Comparison of Retzius-sparing versus anterior robotic-assisted radical prostatectomy in patients with prior transurethral resection of the prostate (TURP)
Comparison of Retzius-sparing versus anterior robotic-assisted radical prostatectomy in patients with prior transurethral resection of the prostate (TURP) Open
Background/objectives Radical prostatectomy (RP) following previous transurethral resection of the prostate (TURP) is technically challenging due to an altered anatomy and fibrosis, often resulting in impaired functional outcomes. Open and…
View article: Diagnostic Value of Micro‐Ultrasound in Identifying Local Recurrence After Radical Prostatectomy
Diagnostic Value of Micro‐Ultrasound in Identifying Local Recurrence After Radical Prostatectomy Open
Purpose The limited resolution of standard transrectal ultrasound (TRUS) has made it difficult to perform biopsies of the prostate bed in cases of suspected local recurrence following radical prostatectomy. The aim of this study was to ben…
View article: Anxiety and Health-related Quality of Life in Men with Prostate Cancer Undergoing Focal Therapy: A Prospective Single-arm Phase 2 Trial
Anxiety and Health-related Quality of Life in Men with Prostate Cancer Undergoing Focal Therapy: A Prospective Single-arm Phase 2 Trial Open
Focal HIFU treatment for localized PCa is associated with a low psychological burden and stable, high health-related QoL. These results demonstrate the enduring impact of this organ-sparing approach on both psychological and QoL outcomes.
View article: Long-term follow-up after initial negative prostate biopsy—comparison of conventional transrectal ultrasound biopsy and mpMRI/transrectal ultrasound fusion guided biopsy
Long-term follow-up after initial negative prostate biopsy—comparison of conventional transrectal ultrasound biopsy and mpMRI/transrectal ultrasound fusion guided biopsy Open
Men with an initial negative biopsy have a low risk of developing localized, metastatic, or deadly PCa during long-term follow-up. The biopsy technique was not significantly associated with different IRs of significant PCa diagnoses. The e…
View article: A Novel Machine Learning-based Predictive Model of Clinically Significant Prostate Cancer and Online Risk Calculator
A Novel Machine Learning-based Predictive Model of Clinically Significant Prostate Cancer and Online Risk Calculator Open
We developed a predictive model for detecting csPCa that exhibited a high ROC-AUC value for internal and external validations. This suggests that the integration of the clinical parameters outperformed each individual predictor. Additional…
View article: Undetectable pre‐radical cystectomy circulating tumour <scp>DNA</scp> status predicts improved oncological outcomes
Undetectable pre‐radical cystectomy circulating tumour <span>DNA</span> status predicts improved oncological outcomes Open
Objective To assess recurrence‐free survival (RFS) in patients with undetectable tumour‐informed circulating tumour DNA (ctDNA) before radical cystectomy (RC) and evaluate if those who converted from detectable to undetectable ctDNA status…
View article: BioPrev-C – development and validation of a contemporary prostate cancer risk calculator
BioPrev-C – development and validation of a contemporary prostate cancer risk calculator Open
Objectives To develop a novel biopsy prostate cancer (PCa) prevention calculator (BioPrev-C) using data from a prospective cohort all undergoing mpMRI targeted and transperineal template saturation biopsy. Materials and methods Data of all…
View article: Evaluation of Proclarix in the diagnostic work‐up of prostate cancer
Evaluation of Proclarix in the diagnostic work‐up of prostate cancer Open
Objectives The use of multiparametric magnetic resonance imaging (mpMRI) has been widely adopted in the diagnostic work‐up for suspicious prostate cancer (PCa) and is recommended in most current guidelines. However, mpMRI lesions are often…
View article: Retrospective analysis of the uptake of active surveillance for low-risk prostate cancer in Zurich, Switzerland
Retrospective analysis of the uptake of active surveillance for low-risk prostate cancer in Zurich, Switzerland Open
OBJECTIVES: Active surveillance for low-risk prostate cancer closely monitors patients conservatively instead of the pursuit of active treatment to reduce overtreatment of insignificant disease. Since 2009, active surveillance has been rec…
View article: Validation of a Zero-Shot Learning Natural Language Processing Tool for Data Abstraction from Unstructured Healthcare Data
Validation of a Zero-Shot Learning Natural Language Processing Tool for Data Abstraction from Unstructured Healthcare Data Open
Objectives: To describe the development and validation of a zero-shot learning natural language processing (NLP) tool for abstracting data from unstructured text contained within PDF documents, such as those found within electronic health …
View article: Limited Value of Bladder Wash Cytology During Follow-Up of Patients With Non-muscle Invasive Bladder Cancer
Limited Value of Bladder Wash Cytology During Follow-Up of Patients With Non-muscle Invasive Bladder Cancer Open
Aims We aimed to assess the performance of bladder wash cytology (BWC) in daily clinical practice in a pure follow-up cohort of patients previously diagnosed with non-muscle invasive bladder cancer (NMIBC). Materials and methods We analyze…
View article: Is Regular Radiographic Upper Urinary Tract Imaging for Surveillance of Non-Muscle Invasive Bladder Cancer Justified?
Is Regular Radiographic Upper Urinary Tract Imaging for Surveillance of Non-Muscle Invasive Bladder Cancer Justified? Open
Patients with non-muscle invasive (NMI) urothelial bladder cancer (BC) are at increased risk for the development of a secondary upper-urinary-tract urothelial carcinoma (UTUC). We aimed to assess the usefulness of routine upper-tract imagi…
View article: Tumor Stent for Chronic Ureteral Obstruction: Which Are Predictors of Stent Failure?
Tumor Stent for Chronic Ureteral Obstruction: Which Are Predictors of Stent Failure? Open
PURPOSE To identify predictors of UROSOFT® tumor stent failure. According to the manufacturer, this reinforced ureteral stent has a maximal dwell time of 6 months. Nonetheless, stent failure may reduce this maximal dwell time. METHODS All …
View article: Prostate cancer detection rate in men undergoing transperineal template‐guided saturation and targeted prostate biopsy
Prostate cancer detection rate in men undergoing transperineal template‐guided saturation and targeted prostate biopsy Open
Objectives To compare prostate cancer (PCa) detection rate of transperineal template‐guided saturation prostate biopsy (SBx) and multiparametric magnetic resonance imaging (mpMRI)/transrectal ultrasound fusion guided targeted biopsy (TBx).…