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View article: EXPRESSION OF EXTRACELLULAR MATRIX METALLOPROTEINASE INDUCER (EMMPRIN) AS A BIOMARKER IN ORAL SQUAMOUS CELL CARCINOMA (OSCC)
EXPRESSION OF EXTRACELLULAR MATRIX METALLOPROTEINASE INDUCER (EMMPRIN) AS A BIOMARKER IN ORAL SQUAMOUS CELL CARCINOMA (OSCC) Open
EMMPRIN is a widely distributed cell surface glycoprotein that belongs to immunoglobulin (Ig) super family. It isinducing the production of extracellular matrix metalloproteinase (MMP) enzymes and play important role in angiogenesis via st…
View article: Network meta-analysis of episiotomy approaches: comparing routine, restrictive, and non-episiotomy strategies and their effects on maternal and neonatal outcomes in primiparous patients
Network meta-analysis of episiotomy approaches: comparing routine, restrictive, and non-episiotomy strategies and their effects on maternal and neonatal outcomes in primiparous patients Open
Background Episiotomy, although occasionally required during labor, can result in postpartum discomfort, perineal trauma, and delayed healing. This study offers a comprehensive comparison of the safety and effectiveness of routine, restric…
View article: Preoperative Colchicine and Conduction Disturbances After Transcatheter Aortic Valve Implantation: A US Retrospective Cohort Analysis
Preoperative Colchicine and Conduction Disturbances After Transcatheter Aortic Valve Implantation: A US Retrospective Cohort Analysis Open
Background Conduction disturbances are frequent complications following transcatheter aortic valve intervention (TAVI), partially driven by inflammation. The anti‐inflammatory role of colchicine on these disorders post TAVI has not been st…
View article: Safety of Permissive Cardiotoxicity of Trastuzumab in Patients with Breast Cancer: A Systematic Review and Meta-Analysis
Safety of Permissive Cardiotoxicity of Trastuzumab in Patients with Breast Cancer: A Systematic Review and Meta-Analysis Open
View article: F-114 | Trends in Cancer and Pulmonary Embolism Related Mortality in Adult US Population: A CDC WONDER Database Analysis from 1999 to 2020
F-114 | Trends in Cancer and Pulmonary Embolism Related Mortality in Adult US Population: A CDC WONDER Database Analysis from 1999 to 2020 Open
View article: Metformin plus lifestyle interventions versus lifestyle interventions alone for the delay or prevention of type 2 diabetes in individuals with prediabetes: a meta-analysis of randomized controlled trials
Metformin plus lifestyle interventions versus lifestyle interventions alone for the delay or prevention of type 2 diabetes in individuals with prediabetes: a meta-analysis of randomized controlled trials Open
Objectives We conducted this meta-analysis of randomized controlled trials (RCTs) to compare the efficacy of adding metformin to lifestyle interventions versus lifestyle interventions alone in individuals with prediabetes. Materials and me…
View article: Impact of SGLT2 Inhibitors on Atrial Fibrillation Recurrence after Catheter Ablation in Type 2 Diabetes Mellitus: A Meta-Analysis of Reconstructed Kaplan–Meier Curves with Trial Sequential Analysis
Impact of SGLT2 Inhibitors on Atrial Fibrillation Recurrence after Catheter Ablation in Type 2 Diabetes Mellitus: A Meta-Analysis of Reconstructed Kaplan–Meier Curves with Trial Sequential Analysis Open
PURPOSE: The role of sodium-glucose cotransporter 2 inhibitors (SGLT2i) in managing cardiovascular outcomes in patients with type 2 diabetes mellitus (T2DM) is evolving. This meta-analysis seeks to explore the influence of SGLT2i on the re…
View article: Safety of masitinib in patients with neurodegenerative diseases: a meta-analysis of randomized controlled trials
Safety of masitinib in patients with neurodegenerative diseases: a meta-analysis of randomized controlled trials Open
View article: Should Medicine be Taught in Leading Medical Languages or the Mother Tongue?
Should Medicine be Taught in Leading Medical Languages or the Mother Tongue? Open
In non-English speaking developing countries, several debates have arisen over choosing the language of instruction in medical education, whether it should be one of the leading medical languages, such as English, or the mother tongue. In …
View article: Efficacy and safety of laparoscopic liver resection versus radiofrequency ablation in patients with early and small hepatocellular carcinoma: an updated meta-analysis and meta-regression of observational studies
Efficacy and safety of laparoscopic liver resection versus radiofrequency ablation in patients with early and small hepatocellular carcinoma: an updated meta-analysis and meta-regression of observational studies Open
View article: Prevalence and Clinical Characteristics of Sleeping Paralysis: A Systematic Review and Meta-Analysis
Prevalence and Clinical Characteristics of Sleeping Paralysis: A Systematic Review and Meta-Analysis Open
Sleep paralysis (SP) is a mixed state of consciousness and sleep, combining features of rapid eye movement (REM) sleep with those of wakefulness. The exact cause of SP is unknown, and its prevalence varies among the studies. We aim to iden…
View article: Masitinib as a neuroprotective agent: a scoping review of preclinical and clinical evidence
Masitinib as a neuroprotective agent: a scoping review of preclinical and clinical evidence Open
Objectives Masitinib, originally developed as a tyrosine kinase inhibitor for cancer treatment, has shown potential neuroprotective effects in various neurological disorders by modulating key pathways implicated in neurodegeneration. This …
View article: Efficacy and safety of laparoscopic liver resection versus radiofrequency ablation in patients with early and small hepatocellular carcinoma: an updated meta-analysis and meta- regression of observational studies
Efficacy and safety of laparoscopic liver resection versus radiofrequency ablation in patients with early and small hepatocellular carcinoma: an updated meta-analysis and meta- regression of observational studies Open
Background Hepatocellular carcinoma (HCC) is the most common type of liver cancer, accounting for 90% of cases worldwide and a significant contributor to cancer-related deaths. This study comprehensively compares the safety and efficacy of…
View article: Prevalence and correlates of fatigue in amyotrophic lateral sclerosis: A systematic review and meta-analysis
Prevalence and correlates of fatigue in amyotrophic lateral sclerosis: A systematic review and meta-analysis Open
Objectives This systematic review and meta-analysis aimed to determine the frequency and correlates of fatigue in patients with amyotrophic lateral sclerosis (ALS). Methods Three databases were searched up to 2nd May 2023 to identify studi…
View article: Clinical characteristics, course, and outcomes of amyotrophic lateral sclerosis overlapping with pregnancy: a systematic review of 38 published cases
Clinical characteristics, course, and outcomes of amyotrophic lateral sclerosis overlapping with pregnancy: a systematic review of 38 published cases Open
View article: Efficacy and safety of isotonic versus hypotonic intravenous maintenance fluids in hospitalized children: an updated systematic review and meta-analysis of randomized controlled trials
Efficacy and safety of isotonic versus hypotonic intravenous maintenance fluids in hospitalized children: an updated systematic review and meta-analysis of randomized controlled trials Open
View article: Efficacy and safety of calcium channel blockers in preventing cardiac siderosis in thalassemia patients: An updated <scp>meta‐analysis</scp> with trial sequential analysis
Efficacy and safety of calcium channel blockers in preventing cardiac siderosis in thalassemia patients: An updated <span>meta‐analysis</span> with trial sequential analysis Open
Objectives Iron overload in patients with thalassemia represents a serious complication by affecting numerous organ systems. This meta‐analysis aims to establish an evidence regarding the effect of amlodipine on cardiac iron overload in th…
View article: COVID-19 Risk Perception and Adherence to Preventive Measures among Medical Students after Receiving COVID-19 Vaccination: A Multicenter Cross-Sectional Study in Egypt
COVID-19 Risk Perception and Adherence to Preventive Measures among Medical Students after Receiving COVID-19 Vaccination: A Multicenter Cross-Sectional Study in Egypt Open
This study aimed to assess the perception of COVID-19 risk and the adherence to protective measures among medical students after vaccination. We conducted a cross-sectional survey on a convenience sample of students from all the 18 governm…