Basma Othman
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View article: Injectable GSK3 inhibitor (Tideglusib) hydrogel versus enhanced β-tricalcium phosphate in tibial bone healing (in vitro and in vivo study)
Injectable GSK3 inhibitor (Tideglusib) hydrogel versus enhanced β-tricalcium phosphate in tibial bone healing (in vitro and in vivo study) Open
This study was carried out to assess the potential effect of a glycogen synthase kinase-3 inhibitor tideglusib hydrogel formulation on bone regeneration and to compare it with Ethoss a beta tricalcium phosphate alloplastic bone substitute …
View article: Five side populations isolated from rat bone marrow‑derived mesenchymal stem cells
Five side populations isolated from rat bone marrow‑derived mesenchymal stem cells Open
Over the past decade, there has been marked enthusiasm surrounding the potential application of mesenchymal stem cells (MSCs) as universally compatible donor cells in the field of regenerative medicine. Due to their distinctive immune‑tole…
View article: The Effect of Cerebrolysin in an Animal Model of Forebrain Ischemic-Reperfusion Injury: New Insights into the Activation of the Keap1/Nrf2/Antioxidant Signaling Pathway
The Effect of Cerebrolysin in an Animal Model of Forebrain Ischemic-Reperfusion Injury: New Insights into the Activation of the Keap1/Nrf2/Antioxidant Signaling Pathway Open
Forebrain ischemia-reperfusion (IR) injury causes neurological impairments due to decreased cerebral autoregulation, hypoperfusion, and edema in the hours to days following the restoration of spontaneous circulation. This study aimed to ex…
View article: Intermittent fasting and probiotics in non-alcoholic fatty liver in rats: interplay between FGF19 and FGF21
Intermittent fasting and probiotics in non-alcoholic fatty liver in rats: interplay between FGF19 and FGF21 Open
Probiotics (PR) and intermittent fasting (IF) are believed to alleviate dysbiosis, which contributes to Non-alcoholic fatty liver disease (NAFLD) pathogenesis. Our study investigated the effect of PR, IF, and their combination (IP) on fatt…
View article: Effectiveness of Psycho-Motivational Training on Improving Social Skills and Emotional Regulation in Patients with Schizophrenia
Effectiveness of Psycho-Motivational Training on Improving Social Skills and Emotional Regulation in Patients with Schizophrenia Open
Background: Schizophrenia is a psychotic condition marked by a lack of understanding of reality and insight, that can be found in symptoms of severe mental disorders such as delusions, hallucinations, chaotic speech, and chaotic behavior, …
View article: The Potential Protective Effect and Underlying Mechanisms of Physiological Unconjugated Hyperbilirubinemia Mediated by UGT1A1 Antisense Oligonucleotide Therapy in a Mouse Model of Cyclosporine A-Induced Chronic Kidney Disease
The Potential Protective Effect and Underlying Mechanisms of Physiological Unconjugated Hyperbilirubinemia Mediated by UGT1A1 Antisense Oligonucleotide Therapy in a Mouse Model of Cyclosporine A-Induced Chronic Kidney Disease Open
Cyclosporine A (CSA) is an immunosuppressive drug that has improved transplant survival rates. However, its use is often limited because it is thought to be linked to the development of chronic kidney disease after kidney transplants. This…
View article: Protective Effect of Artemisinin on the Placenta of L-NAME Induced rat model of Preeclampsia
Protective Effect of Artemisinin on the Placenta of L-NAME Induced rat model of Preeclampsia Open
Preeclampsia (PE) is a pregnancy induced hypertensive disorder and an important cause of maternal and fetal morbidity and mortality.It affects about 3 -8% of all pregnancies worldwide.Placental factors that arise from placental hypoxia/isc…
View article: Enhanced Autophagic Flux, Suppressed Apoptosis and Reduced Macrophage Infiltration by Dasatinib in Kidneys of Obese Mice
Enhanced Autophagic Flux, Suppressed Apoptosis and Reduced Macrophage Infiltration by Dasatinib in Kidneys of Obese Mice Open
Obesity causes renal changes (ORC), characterized by defective renal autophagy, lipogenesis, enhanced macrophage infiltration and apoptosis. We hypothesize that Dasatinib, a tyrosine kinase inhibitor, may ameliorate changes associated with…
View article: Mesenchymal stem cells ameliorate ischemia reperfusion induced acute kidney injury in rat model
Mesenchymal stem cells ameliorate ischemia reperfusion induced acute kidney injury in rat model Open
Mesenchymal stem cells (MSCs) have generated a great deal of excitement and promise as a potential source of all types of cells for cell-based therapeutic strategies. The present study aimed to evaluate the ameliorative effect of MSCs inje…
View article: Mesenchymal stem cells ameliorate ischemia reperfusion induced acute kidney injury in rat model
Mesenchymal stem cells ameliorate ischemia reperfusion induced acute kidney injury in rat model Open
Mesenchymal stem cells (MSCs) have generated a great deal of excitement and promise as a potential source of all types of cells for cell-based therapeutic strategies. The present study aimed to evaluate the ameliorative effect of MSCs inje…