Basseem Radwan
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Monitoring excited-state relaxation in a molecular marker in live cells–a case study on astaxanthin Open
Small molecules are frequently used as dyes, labels and markers to visualize and probe biophysical processes within cells. However, very little is generally known about the light-driven excited-state reactivity of such systems when placed …
Toward Raman Subcellular Imaging of Endothelial Dysfunction Open
Multiple diseases are at some point associated with altered endothelial function, and endothelial dysfunction (ED) contributes to their pathophysiology. Biochemical changes of the dysfunctional endothelium are linked to various cellular or…
Monitoring excited-state relaxation in a molecular marker in live cells–a case study on astaxanthin Open
Small molecules are frequently used as dyes, labels and markers to visualize and probe biophysical processes within cells.
Labeled vs. Label-Free Raman Imaging of Lipids in Endothelial Cells of Various Origins Open
Endothelial cells (EC) constitute a single layer of the lining of blood vessels and play an important role in maintaining cardiovascular homeostasis. Endothelial dysfunction has been recognized as a primary or secondary cause of many disea…
The Safety of Chelators for Iron Overload in Sickle Cell Disease: A Brief Systematic Review Open
Sickle cell disease (SCD) is a group of disorders that affects hemoglobin due to a mutation of the hemoglobin beta gene (HBB) on chromosome 11. Patients with SCD have atypical hemoglobin molecules called hemoglobinS (HbS), which distort er…
Curcumin Enhances the Efficacy of 5-FU in Colo205 Cell Lines Open
5-FU is the main antimetabolite drug used in treating colon cancer. However, treatment success is only 10–15% due to drug resistance. To avoid resistance and improve treatment efficacy without increasing general toxicity, activity of combi…